United States v. Arman Abovyan ( 2021 )


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  •         USCA11 Case: 19-10676     Date Filed: 02/22/2021   Page: 1 of 51
    [PUBLISH]
    IN THE UNITED STATES COURT OF APPEALS
    FOR THE ELEVENTH CIRCUIT
    ________________________
    No. 19-10676
    ________________________
    D.C. Docket No. 9:18-cr-80122-DMM-1
    UNITED STATES OF AMERICA,
    Plaintiff-Appellee,
    versus
    ARMAN ABOVYAN,
    Defendant-Appellant.
    ________________________
    Appeal from the United States District Court
    for the Southern District of Florida
    ________________________
    (February 22, 2021)
    Before WILLIAM PRYOR, Chief Judge, HULL and MARCUS, Circuit Judges.
    HULL, Circuit Judge:
    After a jury trial, Arman Abovyan appeals his convictions and sentences for
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    conspiring to commit healthcare fraud, conspiring to possess with intent to
    dispense controlled substances, and seven counts of unlawfully dispensing a
    controlled substance. On appeal, he argues that insufficient evidence supported his
    convictions, the jury instructions were improper, and his sentences were
    improperly calculated. After review, and with the benefit of oral argument, we
    affirm Abovyan’s convictions and sentences.
    I. FACTUAL BACKGROUND
    This healthcare fraud conspiracy was orchestrated by Kenneth Chatman, a
    convicted felon with no medical training. Chatman owned and operated two
    substance-abuse treatment centers, Reflections Treatment Center (“Reflections”)
    and Journey to Recovery (“Journey”), in South Florida.1 The Facilities offered
    various levels of outpatient substance-abuse treatment for individuals suffering
    from drug and alcohol addiction, some of whom resided at separate “sober homes”
    and “halfway houses.” 2
    The defendant Arman Abovyan was a primary-care physician, board-
    certified in internal medicine, with a private medical practice. Although Abovyan
    1
    When we refer to Reflections and Journey collectively, we use the term “Facilities.” On
    paper, Chatman’s wife owned the Facilities because Chatman was a convicted felon. But in
    reality, Chatman was the true owner and operator.
    2
    At trial, the terms “sober homes” and “halfway houses” were used for residences for
    patients attending outpatient drug treatment.
    2
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    had no prior experience in substance-abuse medicine, Chatman recruited him to be
    the medical director of the Facilities.
    In July 2016, Abovyan became medical director of Reflections and of
    Journey when it opened in October 2016. As medical director, Abovyan’s duties
    included providing substance-abuse treatment, authorizing and ordering drug
    testing, and prescribing drug-treatment medication. Abovyan’s employment
    contract specified that he would work around 18.5 hours per week and be paid
    $11,000 per month. In practice, Abovyan was present at the Facilities only about
    nine hours per week or less. Abovyan remained the Facilities’ medical director
    until federal authorities executed search warrants and shut them down in December
    2016. Below, we describe the healthcare fraud scheme and Abovyan’s role in it.
    A. The Healthcare Fraud Scheme
    Chatman’s healthcare fraud scheme involved over 20 individuals. 3 Chatman
    paid kickbacks to the owners of sober homes and halfway houses in exchange for
    them sending their patients to the Facilities for treatment and drug testing.
    For example, Anthony Jackson testified that he met Chatman around August
    3
    Before Abovyan’s trial, Chatman pled guilty to conspiring to commit healthcare fraud,
    conspiring to commit money laundering, and conspiring to commit sex trafficking and was
    sentenced to imprisonment terms of 120 months on the healthcare fraud conspiracy, 240 months
    on the money laundering conspiracy, and 330 months on the sex trafficking conspiracy, all to run
    concurrent.
    3
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    2015, when Jackson owned a sober home. 4 Most of Jackson’s residents had
    insurance. Chatman paid Jackson to send his sober home residents to attend
    Reflections for treatment and testing. Jackson later became program director at
    Reflections.
    Chatman required his employees at the Facilities to collect urine and saliva
    from their patients three times per week and send them for drug testing to specific
    toxicology labs, including Smart Lab and Ally Clinical Diagnostics (“Ally”). The
    labs charged thousands of dollars per specimen tested, for which the labs billed the
    Facilities’ patients’ insurance. In return, Chatman received kickbacks for sending
    specimens to Smart Lab and Ally for testing.
    For example, from the summer of 2016 until 2017, Bosco Vega was a sales
    representative for Smart Lab. Its CEO was Hawkeye Wayne. Vega testified that
    the more testing he procured for Smart Lab, the more he was paid in commissions
    and the more kickbacks Chatman received. Vega had an arrangement with
    Chatman and Wayne, whereby Vega gave Chatman half of his net commissions as
    a kickback on all urine testing Reflections ordered from Smart Lab through Vega.5
    During Vega’s time as a Smart Lab sales rep, he paid Chatman kickbacks of
    4
    Before Abovyan’s trial, Jackson pled guilty to conspiring to commit healthcare fraud
    and was sentenced to 42 months’ imprisonment.
    5
    Before Abovyan’s trial, Vega pled guilty to money laundering but had not been
    sentenced.
    4
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    approximately $40,000 in cash. Vega also was paid between $10,000 and $20,000
    per month to “oversee[]” the organization and transportation of samples to Smart
    Lab.
    Similarly, Stefan Gatt worked for Ally as a medical sales representative.
    Gatt testified that, starting in February 2016, he paid Chatman kickbacks to use
    Ally for saliva testing.6 Gatt was a partial owner of Journey with Chatman. Gatt
    admitted that he oversaw the urine and saliva testing that both Smart Lab and Ally
    provided for the Facilities’ patients.
    B. Abovyan’s Role in Ordering Tests
    To help Chatman submit as many specimens as possible to Smart Lab and
    Ally, Abovyan ordered and authorized excessive lab drug testing that was
    medically unnecessary. Abovyan’s predecessor at Reflections was Dr. Aron
    Tendler. Chatman fired Dr. Tendler after he attempted to curtail the excessive and
    medically unnecessary testing at Reflections. Chatman recruited Abovyan as
    Tendler’s replacement.
    When Abovyan started at Reflections, he wrote a letter adopting the testing
    regime that Dr. Tendler had unsuccessfully tried to curtail. The July 15, 2016,
    letter, typed on Reflections letterhead and signed by Abovyan, stated:
    6
    Before Abovyan’s trial, Gatt pled guilty to conspiring to commit healthcare fraud and
    finished serving his 18 months’ sentence.
    5
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    I am the new Medical Director for Reflections Treatment Center. Prior
    to my hire, [Dr. Tendler] left his post without reviewing and signing off
    on client charts. We have been unsuccessful in our attempts to reach
    him and rectify this situation.
    As a result, I have reviewed the orders and progress notes. I agree with
    the factual and medical recommendations of the previous Medical
    Director.
    Abovyan then wrote “standing orders” authorizing the testing of the
    Facilities’ patients’ urine at least two to three times weekly. For example, one of
    these standing orders, titled “Urine Drug Test Protocol,” signed by Abovyan,
    established that, for every patient, “Point of Care Cup testing will be used for rapid
    detection and the specimen will be sent to a separate lab for Confirmation.” 7
    Abovyan’s standing order authorized a laboratory testing frequency of “2-3
    Scheduled times per week and up to 2 random times per week” and stated that
    Abovyan “confirm[ed] that the Urine Drug Screening & Confirmation tests
    ordered by me are medically necessary for the diagnosis and treatment plan and
    will be documented in patients[’] chart[s] as medically necessary.” Based on that
    protocol, Abovyan signed consent forms authorizing Smart Lab “to perform the
    toxicology testing for patient specimens from [the Facilities] based off of the
    individual requisition forms.”
    7
    There are different levels of urine testing. A “point of care” test is done in the office
    where the patient is getting care and involves an inexpensive cup and dipstick. Lab testing, also
    called “definitive or confirmatory testing,” is not done on-site, is expensive, and requires a
    doctor’s order.
    6
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    Facilities employees then used these requisition forms to order the lab drug
    tests for each individual specimen. The Facilities used different requisition forms
    depending on the type of specimen (urine or saliva) because they used Smart Lab
    for urine testing and Ally for saliva testing. The Smart Lab requisition forms had
    the Smart Lab logo at the top, a space for patient information, diagnosis codes, and
    a series of boxes to check to indicate which types of drugs the urine was to be
    tested for. Because Abovyan established standing orders and consent forms for
    Smart Lab testing, he did not sign each requisition form. Instead, Abovyan’s name
    was listed as the “Ordering Provider” on each form.
    Ally’s requisition forms were similar to Smart Lab’s, with an Ally logo at
    the top, a space for patient information, and drug-test-request checkboxes. Instead
    of establishing standing orders and consent forms like he did with Smart Lab,
    Abovyan pre-signed Ally’s testing requisition forms, leaving the patient
    information blank, but checking boxes for full comprehensive tests for all available
    drugs.
    Co-conspirator Gatt testified that Abovyan pre-signed Ally saliva testing
    requisition forms so that Gatt and others could make copies of them. Abovyan
    knew that they were photocopying his pre-signed requisition forms so that he “did
    not have to continually sign off on each individual form.” Gatt testified that either
    he or a staff member filled in the patient information and checked boxes for
    7
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    various testing, and Abovyan knew about it because Gatt filled out one of the
    sheets in front of Abovyan and Abovyan signed it.
    These tests were not specialized to a named patient or a patient’s
    background. Rather, Abovyan admitted that he established this testing protocol
    because that was “what Kenneth Chatman . . . wanted.” Even if a patient were
    addicted only to cocaine, Abovyan admitted they would “test for everything.” In
    many instances, this meant that a lab tested specimens for over 100 substances,
    including drugs that would not meaningfully inform treatment because they were
    non-addictive or rarely abused. Each lab urine test costs between $1,000 and
    $6,000.8
    Patricia LaFrance, a Behavioral Health Technician, worked directly for
    Chatman at Reflections from July 2015 until around October 2016 and at Journey
    from October 2016 until the Facilities closed. LaFrance monitored patient
    urinalysis. LaFrance collected a cup of urine from every patient three times per
    week and performed a cup and dipstick test on every sample. Regardless of the
    cup test results, LaFrance sent the urine to the lab for further testing using lab
    requisition forms that Abovyan authorized in his standing orders. Another
    employee trained LaFrance to fill out the Smart Lab requisition forms with the
    8
    Most uninsured patients did not receive this expensive lab testing and were tested only
    once per month with an on-site cup/dipstick test that cost around $3.
    8
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    patient’s information and to check the appropriate boxes so that the lab tested the
    sample for a myriad of different drugs.
    When a patient did not show up for testing, various staff provided their own
    urine for lab analysis, at Chatman’s direction. LaFrance also collected saliva
    samples and filled out Abovyan’s pre-signed Ally requisition forms, which she
    gave to Gatt.
    C. Abovyan’s Role in “Treatment”
    The Facilities also made money by billing patients’ insurance for outpatient
    “treatment.” The Facilities’ treatment services included therapy sessions, medical
    checkups, and drug-treatment medication. In reality though, the patients received
    no real medical treatment.
    In addition to excessive drug testing orders, Abovyan prescribed Suboxone
    to his patients, even though he was not licensed to do so. Suboxone is a controlled
    substance that contains the Schedule III narcotic buprenorphine. The Drug
    Addiction Treatment Act of 2000 requires physicians who are not addiction
    specialists to take a training course and obtain a special license before they can
    prescribe buprenorphine for addiction treatment, in light of the drug’s potential for
    abuse and risk of side effects, including death. See 
    21 U.S.C. § 823
    (g).
    After completing a specialized training course and registering, doctors apply
    for a DEA certificate and receive an X Number, which allows them to lawfully
    9
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    prescribe buprenorphine for addiction treatment. This special license, including
    the X Number, is not needed when buprenorphine is prescribed to treat other
    things, like pain. Until September 2016, Abovyan did not have an X Number.
    To get around the X Number requirement between July and September,
    2016, Abovyan indicated on the Facilities’ patients’ buprenorphine prescriptions a
    diagnosis of “pain” or “withdrawal” (instead of drug addiction), even though
    patients’ charts did not indicate that they were, in fact, experiencing pain or
    withdrawal.
    Although ordering drug tests and prescribing buprenorphine, Abovyan often
    did so without actually examining patients, making assessments, or creating
    individualized treatment plans. Then, Abovyan rarely showed or discussed the lab
    drug test results with patients. Although Abovyan noted in many patient charts,
    “[r]eviewed and will discuss at next patient encounter,” there was no such follow-
    up. Even when patients tested positive for drug use, there was no evidence in
    patients’ charts or elsewhere that Abovyan discussed this with patients or modified
    treatment. In some instances, Abovyan noted that a patient was “doing well” or
    “normal” or “clean for a while” even though the test results indicated otherwise.
    Despite being the Facilities’ main doctor, Abovyan largely delegated his
    treatment duties. He pre-signed prescription pads for his nurses to fill in the
    patient name, drug, and diagnosis without his being present. Jackson testified that
    10
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    he saw Abovyan’s nurse practitioners with blank prescription pads signed by
    Abovyan. Abovyan also gave the nurses his log-in credentials to edit patients’
    electronic medical records. When Abovyan did meet with the Facilities’ patients,
    it typically was for only around five minutes. Reflections even stored medications
    on site, and, if a patient was prescribed buprenorphine, Reflections would give the
    patient the medication from storage instead of waiting until the prescription was
    filled at the pharmacy.
    D. Federal Investigation
    When the Facilities were shut down in December 2016, the Federal Bureau
    of Investigation (“FBI”) agents discovered Abovyan’s signature on stacks of Ally
    testing requisition forms. The test forms had no patient names or information but
    did have diagnosis codes completed on the forms and boxes pre-checked to request
    full-panel lab testing.
    Agents also searched the storage unit of Tina Barbuto, the clinical director of
    Reflections and Abovyan’s codefendant. Agents found, inter alia, patient
    documents, test results, and pill bottles containing controlled substances, including
    Suboxone—which contains buprenorphine—that had been prescribed by Abovyan
    to the Facilities’ patients. Jackson testified he saw Barbuto with blank prescription
    pads signed by Abovyan. At Reflections, agents found a November 2016 letter
    directed to Abovyan from an insurance company, which stated that, “[d]ue to
    11
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    ongoing and serious investigations regarding member safety and potential
    insurance fraud, we are temporarily suspending all approval of authorization for
    treatment at Reflections Treatment Center and payment of claims for any treatment
    at this facility.”
    In April 2017, a UnitedHealthcare investigator interviewed Abovyan.
    Abovyan said that working at Reflections “was easy money,” but also the “biggest
    mistake of his life.” Abovyan admitted that he ordered the lab urine tests for
    patients at Reflections to be conducted two to three times per week.
    The FBI interviewed Abovyan in June 2017. Abovyan admitted that he: (1)
    signed the standing lab orders; (2) ordered whatever lab tests that Chatman wanted
    three times per week per patient 9; (3) provided the nurse practitioners with pre-
    signed, blank prescription pads; and (4) received additional payments for detox and
    treatment services, and was paid $5,000 per month “so that Kenny Chatman could
    use [Abovyan’s] medical license to bill insurance.”10
    II. INDICTMENT & TRIAL
    In 2018, a superseding indictment charged Abovyan and Tina Barbuto with:
    9
    Abovyan told the FBI that he reviewed the lab test results for each patient and signed the
    electronic medical records indicating that he reviewed the results. However, at trial, patients and
    others testified that he did not review the test results with patients.
    10
    In some months, the $5,000 appears to be over and above his $11,000 salary, as the
    record shows that he was paid $19,000 in October and $17,300 in December 2016. In November
    2016, he was paid $15,300.
    12
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    conspiracy to commit healthcare fraud, in violation of 
    18 U.S.C. § 1349
     (Count
    One); conspiracy to possess with intent to distribute and dispense controlled
    substances, including buprenorphine and others, in violation of 
    21 U.S.C. § 846
    (Count Two); unlawful dispensing of a controlled substance, buprenorphine, to
    specific patients (Counts Three through Nine), in violation of 
    21 U.S.C. § 841
    (a)(1) and 
    18 U.S.C. § 2
    ; and possession with intent to distribute controlled
    substances, in violation of § 841(a)(1) and § 2 (Count Ten). Codefendant Barbuto
    pled guilty to conspiracy to commit healthcare fraud. Chatman and around 15
    others were already charged in separate indictments for their roles in the healthcare
    fraud scheme.
    During Abovyan’s eight-day jury trial, the government presented over 20
    witnesses and overwhelming evidence of the above healthcare fraud scheme at the
    Facilities. Among the witnesses, the government called former employees of
    Smart Lab, Ally, and the Facilities; nurse practitioners; an expert on addiction
    medicine; former Reflections patients; Abovyan’s private practice manager; the
    UnitedHealthcare investigator; and several FBI agents. Three witnesses, Jackson,
    Vega, and Gatt, were already convicted for their roles in the scheme. The evidence
    also included thousands of pages of patient records, supporting documents, and
    photographs.
    While the above evidence recounted Abovyan’s overall role in the scheme,
    13
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    we now detail more testimony about Abovyan’s conduct.
    A. Abovyan’s Two Nurse Practitioners
    Andrea Buehler was a nurse practitioner who worked for Abovyan from
    September 2016 until January 2018. Buehler did office work for Abovyan’s
    private practice. Initially, Abovyan would have Buehler go to Reflections on
    Mondays and Wednesdays for around three hours each day. Sometimes Abovyan
    accompanied her, sometimes not. At first, Abovyan spent up to three hours with
    her there each day, but he was there less as time went on. Later on, Buehler went
    to Journey exclusively around twice per week; Abovyan accompanied Buehler to
    Journey only once or twice.
    For each patient at Reflections and later at Journey, Buehler discussed the
    patient’s drug use, did a physical examination, and sometimes wrote prescriptions.
    She never discussed drug test results with patients. Buehler wrote prescriptions for
    buprenorphine on pre-signed prescription pads, and Abovyan instructed her to
    write “drug dependence pain withdrawal” as the prescription diagnosis. She
    accessed patients’ electronic medical records with Abovyan’s log-in credentials.
    Lindsey Callaghan was a nurse practitioner who worked for Abovyan from
    around June until October 2016. For Abovyan’s private practice patients,
    Callaghan would see patients for routine physicals, sick visits, and medication
    refills. Callaghan went to Reflections on Tuesday and Thursday mornings for
    14
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    around four hours each day. She refilled patients’ medications and performed
    quick physicals. Abovyan sometimes accompanied her to Reflections but did not
    always stay the entire time. Callaghan wrote prescriptions on a pre-signed
    prescription pad that Abovyan gave her. At Abovyan’s instruction, Callaghan
    wrote “Drug dependence, withdrawal, pain” as the diagnosis on the prescriptions.
    Generally, Callaghan did not review any drug test results. She also accessed
    patients’ electronic medical records with Abovyan’s log-in credentials.
    B. Patients’ Testimony
    Patient A.B. was an insured Reflections patient addicted to heroin. She
    became a patient on August 31, 2016. A.B. stayed at a halfway house and attended
    therapy at Reflections. She said that, during group therapy sessions at Reflections,
    her fellow patients “were nodding out” and “obviously high.” A.B.’s fellow
    patients and even the managers of her halfway house were using drugs. A.B.
    witnessed Chatman give other patients “street drugs.” Although A.B. remained
    drug-free at first, she became desperate and started using heroin again. When she
    told Chatman that she was using heroin again, he said, “okay.” After that, A.B.
    overdosed on heroin at the halfway house. Another patient overdosed and died at
    the halfway house.
    Reflections tested A.B.’s urine every day she attended Reflections. Yet
    neither Abovyan nor the nurse practitioners ever talked to her about the results.
    15
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    Even though A.B.’s urine tested positive for heroin, nothing about her treatment
    changed. Reflections also tested A.B.’s saliva, and she never saw the results. A.B.
    spoke to Abovyan only once for about 20 minutes during her initial visit. She
    received her prescriptions, including Suboxone, from a nurse practitioner written
    on pre-signed prescription pads. A.B. testified that the Suboxone “didn’t really
    help” her, but she continued to take it because “[she] knew [she] could get high off
    of it.”
    Patient H.F. was another insured Reflections patient starting in July 2016.
    She was prescribed Suboxone and subjected to rigorous blood, urine, saliva, and
    allergy testing, despite not having allergies. Her urine was lab tested about four
    times per week—a frequency that she felt “unnecessary to be able to catch
    someone using.” H.F. never saw the results of any tests. Chatman made it difficult
    for patients to leave treatment. When H.F. decided to leave, Chatman kept her
    identification, phone, clothes, and medication under his control.
    Patient J.B. was an insured patient at Reflections in 2016. J.B. saw Abovyan
    once, and Abovyan did not spend much time with her. Abovyan prescribed her
    three different anxiety medications. J.B. did not see Abovyan again, but she
    continued receiving prescriptions with Abovyan’s signature on them. J.B. saw pre-
    signed prescription pads bearing Abovyan’s signature on Chatman’s desk. J.B.
    lived in a halfway house during her Reflections treatment and did not have to pay
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    rent. Her fellow Reflections patients in the halfway house were drinking and using
    drugs, and, at one point, there were “needles everywhere.” One patient overdosed
    in the house.
    During his FBI interview, Abovyan explained his attitude about patients’
    drug use after they left daily “treatment” at Reflections and returned to the halfway
    houses: “whatever happens happens.”
    C. Dr. Kelly Clark
    The government called Dr. Kelly Clark as an expert witness. Dr. Clark, a
    board-certified physician in addiction medicine and psychiatry, is the President of
    the American Society of Addiction Medicine. Dr. Clark spent 100 hours reviewing
    patient files and other documents from the Facilities. She explained the legal
    requirements and best practices for addiction treatment centers and their medical
    duties, and how Abovyan failed to follow them. As to drug tests, Dr. Clark
    testified that: (1) drug testing always should be tailored to the patient, especially
    when ordering expensive confirmatory lab testing; (2) Abovyan improperly
    ordered across-the-board lab testing for every patient multiple times per week,
    every week; (3) a doctor “[a]bsolutely” should discuss the outcome of each test
    with the patient, particularly if they fail; and (4) there was no documentation in the
    charts that test results were ever discussed with the Facilities’ patients.
    As to prescriptions, Dr. Clark explained that: (1) Florida law does not allow
    17
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    nurse practitioners to practice medicine without the supervision of a physician; (2)
    nurse practitioners may not write controlled substance prescriptions on a
    prescription pad that the doctor already has signed; (3) it is never appropriate for a
    doctor to sign blank prescriptions and give them to a staff member to fill in the
    patient name and drug; and (4) a doctor should not share his own log-in
    information for a patient’s medical record with others.
    As to buprenorphine, Abovyan improperly prescribed it without examining
    the patient, having a doctor–patient relationship, or making an assessment and
    individualized treatment plan. Dr. Clark testified that: (1) Abovyan signed
    prescriptions for buprenorphine to treat “pain/withdrawal”; (2) there was no
    documentation in the charts that the patients, in fact, had pain or withdrawal; and
    (3) those prescriptions were written to treat opioid addiction—and not for a
    withdrawal period, but as ongoing management.
    Dr. Clark also testified that: (1) the amounts billed for urine testing were
    “outrageous”; (2) each lab test cost from over $1,000 to over $6,000 per urine
    specimen; (3) testing was done two to three times per week, with no patient follow-
    up; and (4) these tests thus were not used for treatment purposes.
    Dr. Clark discussed the buprenorphine prescriptions charged in Counts
    Three through Nine. The Reflections patient in Count Three was E.L., who had an
    opioid and cocaine addiction. On July 12, Reflections sent E.L.’s urine sample to
    18
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    Smart Lab for an “extraordinarily high” 100-panel drug test that included drugs not
    ordinarily tested in the treatment or assessment of an addiction patient. On both
    July 13 and July 15, E.L.’s urine was extensively tested again. E.L.’s saliva was
    tested on July 14 and 28. Dr. Clark testified that “[t]here [was] no reason for doing
    both” saliva and urine tests simultaneously.
    On July 20, 2016, Abovyan prescribed E.L. Suboxone for “pain” and
    “withdrawal,” even though E.L.’s chart had no indication that he was experiencing
    pain or withdrawal or that Abovyan had seen him. Dr. Clark testified that the
    Suboxone prescription “was not for a legitimate medical purpose.”
    E.L.’s three July drug tests showed continued drug use. After E.L. stopped
    coming to Reflections, Abovyan electronically signed all three July test results
    without any patient discussion. Yet, Abovyan added the note, “Reviewed and will
    discuss at next patient encounter.” There was no follow-up discussion. Dr. Clark
    testified that the manner in which the urine testing was performed—ordering
    additional tests before receiving the results of prior tests and not discussing those
    results with E.L.—was “[n]ot for a legitimate medical purpose.” This same pattern
    continued with the other patients.
    Counts Four and Eight involved Reflections patient H.F., who had cocaine,
    opioid, and alcohol addictions. H.F.’s urine was also tested by labs at an
    “inappropriate” frequency: July 7, 8, 9, 11, 13, 15, 22, and 24. Although many
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    tests revealed continued drug abuse, Abovyan electronically signed them with his
    standard notation, “Reviewed and will discuss at next patient encounter.” There
    was no follow-up discussion.
    On July 25, 2016, Abovyan prescribed H.F. Suboxone with a
    “pain/withdrawal” diagnosis (Count Four) and, a month later, on August 29,
    Abovyan again prescribed H.F. Suboxone for drug dependence, pain, and
    withdrawal (Count Eight). Dr. Clark explained that, because H.F.’s actual
    diagnosis was drug addiction, Abovyan could not have lawfully prescribed
    Suboxone without an X Number, which he did not have.
    Count Five involved Reflections patient A.C., who had an opioid addiction.
    A.C.’s urine was tested on June 15, 17, 20, 22, 27, and 29, and July 1, 4, 6, 11, 13,
    and 15, 2016. On July 27, Abovyan signed the results as “normal,” even though
    results showed tampering and drug abuse. On August 4, Abovyan wrote a progress
    note stating that A.C. was “clean for a while,” which plainly contradicted A.C.’s
    failed drug tests that Abovyan had reviewed and signed days earlier. On July 25,
    Abovyan prescribed A.C. Suboxone with a “pain/withdrawal” diagnosis. Again,
    Dr. Clark concluded that this Suboxone prescription was illegitimate because
    Abovyan falsely indicated that it was meant to treat “pain/withdrawal,” when it
    was in fact treating drug addiction, and Abovyan did not yet have an X Number.
    Count Six involved Reflections patient D.W., who had a cocaine and opioid
    20
    USCA11 Case: 19-10676      Date Filed: 02/22/2021    Page: 21 of 51
    addiction. The results of D.W.’s urine test on July 15, 2016, indicated tampering,
    yet Abovyan signed off on the results as “normal.” Abovyan’s progress notes
    stated that D.W. was “doing well,” even though he repeatedly failed drug tests.
    Although D.W. did not complain of pain, Abovyan prescribed Suboxone for
    “withdrawal/pain” on July 27, 2016.
    Count Seven involved Reflections patient C.D., who came for an opioid
    addiction treatment from June until August 2016. C.D. provided urine specimens
    multiple times per week for expensive lab testing. Dr. Clark testified that the
    frequency of C.D.’s testing was “inappropriate” and lacked utility, that the money
    billed was “amazing,” and that the results were never discussed with the patient.
    Although C.D. did not complain of pain, Abovyan prescribed Suboxone for
    “pain/withdrawal” on August 3, 2016. In reality, Abovyan was prescribing the
    Suboxone for treatment of an opioid addiction, but he still did not have the
    required X Number.
    Count Nine involved Reflections patient A.B., who had no pain complaints.
    On August 31, Abovyan, without an X Number, prescribed A.B. Suboxone for
    drug dependence, withdrawal, and pain.
    Dr. Clark explained that Abovyan pretextually prescribing Suboxone for
    “pain/withdrawal” without an X Number was only one of many factors underlying
    her opinion that Abovyan’s prescriptions were not for a legitimate medical
    21
    USCA11 Case: 19-10676     Date Filed: 02/22/2021    Page: 22 of 51
    purpose. Dr. Clark explained that Suboxone is an excellent medication for use in
    treatment of an opioid disorder. But Abovyan was only prescribing controlled
    substances and was not treating his patients. Medical treatment requires assessing
    the information, working with the patient, coming up with a treatment plan for that
    patient, getting more information, following up on tests and reviewing them with
    the patient, assessing the additional information, and working more with the patient
    and the treatment plan. None of that occurred here. Abovyan’s patients repeatedly
    failed their drug tests, but he and his nurses never talked about it with them.
    “There was no treatment.”
    Dr. Clark also noticed that “scholarship” patients without insurance
    generally would not receive a single expensive 100-panel lab test. Scholarship
    patients received a 12-panel cup/dipstick test once per month that cost a few
    dollars.
    At the close of the government’s evidence, Abovyan moved for judgment of
    acquittal under Federal Rule of Criminal Procedure 29, which the district court
    denied as to Counts One through Nine and reserved ruling as to Count Ten.
    D. Defense and Verdict
    Abovyan’s defense was that he was an “unwitting patsy,” who was used by
    Chatman and others for their criminal scheme. Abovyan did not testify, but
    presented an expert witness, Dr. Kenneth Starr, who is a board-certified physician
    22
    USCA11 Case: 19-10676       Date Filed: 02/22/2021     Page: 23 of 51
    in emergency and addiction medicine. Dr. Starr spent “[m]aybe six” hours
    preparing for the case and did not review any patient files. Dr. Starr confirmed that
    buprenorphine may be prescribed for pain without an X Number, but that the
    X Number is required for use in addiction treatment. Dr. Starr admitted that it was
    not a common practice to pre-sign blank prescriptions, and that the drugs found in
    some of Abovyan’s patients’ test results would be something that he would want to
    discuss with the patients. At the close of evidence, Abovyan renewed his Rule 29
    motion, and the district court maintained its earlier ruling.
    In closing argument, Abovyan’s counsel acknowledged that “[Gatt] and
    Kenny Chatman essentially conspired . . . to defraud the insurance companies,”
    and LaFrance “dummied up these [requisition] forms.” But he argued that
    “Abovyan had no knowledge” about excessive urine testing. The jury convicted
    Abovyan on Counts One through Nine and acquitted him on Count Ten. The
    district court denied Abovyan’s motion for judgment notwithstanding the verdict
    or for a new trial.
    The district court sentenced Abovyan to 120 months’ imprisonment on his
    Counts One through Eight convictions, to run concurrently, and a consecutive
    15-month sentence on his Count Nine conviction. The district court ordered
    $1,058,097.88 in restitution to the defrauded insurance companies.
    23
    USCA11 Case: 19-10676        Date Filed: 02/22/2021   Page: 24 of 51
    III. SUFFICIENCY OF THE EVIDENCE
    On appeal, Abovyan argues that the government’s evidence is insufficient to
    support his convictions. We review de novo Abovyan’s sufficiency-of-the-
    evidence claims, taking all evidence and drawing all reasonable inferences in the
    light most favorable to the government. United States v. Chalker, 
    966 F.3d 1177
    ,
    1184 (11th Cir. 2020).
    A. Conspiracy to Commit Healthcare Fraud (Count One)
    Abovyan accepts that the healthcare fraud conspiracy existed at the
    Facilities, but contends the government’s evidence was insufficient to prove his
    knowledge of and participation in it. At most, he argues, the government showed
    negligent medical practices on his part, not willful participation in a criminal
    conspiracy. He asserts that there is not “a shred of evidence” that he agreed with
    anyone to engage in healthcare fraud and that “the [g]overnment still has not
    identified a single text, email, document, or snippet of testimony that there was
    ever any conversation or communication between Abovyan and any other person
    about engaging in any illegal act.”
    “For a defendant to be found guilty of conspiracy, the government must
    prove beyond a reasonable doubt (1) that a conspiracy existed; (2) that the
    defendant knew of it; and (3) that the defendant, with knowledge, voluntarily
    joined it.” United States v. Vernon, 
    723 F.3d 1234
    , 1273 (11th Cir. 2013)
    24
    USCA11 Case: 19-10676       Date Filed: 02/22/2021   Page: 25 of 51
    (quotation marks omitted). “Because the crime of conspiracy is predominantly
    mental in composition, it is frequently necessary to resort to circumstantial
    evidence to prove its elements.” United States v. Toler, 
    144 F.3d 1423
    , 1426 (11th
    Cir. 1998) (quotation marks and citations omitted).
    A healthcare fraud conspiracy exists when defendants agree to submit false
    claims to a healthcare benefit program, such as an insurance plan. See United
    States v. Ruan, 
    966 F.3d 1101
    , 1142 (11th Cir. 2020); 
    18 U.S.C. §§ 24
    (b), 1347.
    “[A] defendant can be convicted of conspiracy if the evidence demonstrates that he
    was aware of the conspiracy’s essential nature, even if he did not know all of its
    details, played only a minor role in the overall scheme, did not have direct contact
    with other alleged co-conspirators, or did not participate in every stage of the
    conspiracy.” United States v. Sosa, 
    777 F.3d 1279
    , 1290 (11th Cir. 2015).
    First, we reject Abovyan’s claim that the government must present direct
    evidence that Abovyan agreed to join the conspiracy. It is well settled that the
    government may prove a conspiracy through circumstantial evidence or inferences
    from the defendant’s conduct. See United States v. Moran, 
    778 F.3d 942
    , 960
    (11th Cir. 2015); United States v. Molina, 
    443 F.3d 824
    , 828 (11th Cir. 2006). The
    government can show participation “through proof of surrounding circumstances
    such as acts committed by the defendant which furthered the purpose of the
    conspiracy.” Moran, 778 F.3d at 961 (quotation marks omitted).
    25
    USCA11 Case: 19-10676       Date Filed: 02/22/2021    Page: 26 of 51
    Second, although largely circumstantial, the government introduced ample
    evidence to support Abovyan’s conviction for conspiring to commit healthcare
    fraud. The evidence showed that Abovyan: (1) created Smart Lab standing orders
    so that the Facilities could order expensive and medically unnecessary lab urine
    tests three times per week per patient; (2) pre-signed requisition forms so that the
    Facilities could order even more unnecessary testing from other labs, like Ally;
    (3) forwent lab testing for uninsured patients; (4) reviewed and signed off on
    certain lab test results without discussing them with the patients; (5) admitted the
    Facilities would “test for everything,” even non-addictive drugs not ordinarily
    tested in addiction treatment; (6) provided his medical record log-in and pre-signed
    prescription pads for his nurses to prescribe drugs to patients without him being
    present; (7) received a letter alerting him that insurance billing issues existed and
    did nothing; (8) admitted that he allowed Chatman to make all testing decisions—
    “what [Chatman] wanted”—even though Chatman had no medical training and the
    testing was excessive; and (9) admitted that he received $5,000 per month for
    Chatman to use his medical license to bill insurance for “treatment” at the
    Facilities.
    Abovyan’s full cooperation with Chatman, along with Abovyan’s own
    medical conduct, advanced the healthcare fraud scheme. The government proved
    Abovyan not only agreed to join the conspiracy but also willfully participated in it
    26
    USCA11 Case: 19-10676        Date Filed: 02/22/2021    Page: 27 of 51
    and knew of its essential nature. See Ruan, 966 F.3d at 1143–44 (finding sufficient
    evidence of conspiracy to commit healthcare fraud where defendant doctors
    (1) ordered “expensive off-site urine screen tests that were medically unnecessary,”
    and (2) “rarely discussed inconsistent test results with patients, whether to counsel
    them into compliance or fire them as patients”); see also United States v. Mateos,
    
    623 F.3d 1350
    , 1362 (11th Cir. 2010) (“While it is hypothetically possible that a
    person under these circumstances could have been ignorant of the [conspiracy to
    commit healthcare] fraud, the jury was entitled to draw the reasonable inference
    from this evidence that [the defendant] was in on the scheme.”).
    Abovyan relies on United States v. Willner, 
    795 F.3d 1297
     (11th Cir. 2015),
    and United States v. Ganji, 
    880 F.3d 760
     (5th Cir. 2018), which reversed
    healthcare fraud conspiracy convictions. The evidence against Abovyan, however,
    is substantially stronger and materially different than in these cases.
    In Willner, we reversed Dr. Abreu’s conviction, despite her being the
    program director at a sleep clinic that defrauded Medicare. 795 F.3d at 1303,
    1305–10. The government contended that Dr. Abreu (1) “falsified patient files” to
    make it appear that patients were eligible for the clinic’s partial hospitalization
    program, and (2) “admitted or participated in the admission of ineligible patients”
    into the program. Id. at 1306, 1309. Although Dr. Abreu admitted some ineligible
    patients (cognitively impaired, elderly patients), no evidence showed that it was
    27
    USCA11 Case: 19-10676       Date Filed: 02/22/2021   Page: 28 of 51
    anything more than “poor admission decisions on occasion.” Id. at 1309. Unlike
    Abovyan, Dr. Abreu did not gain anything from the criminal conspiracy. Id. at
    1310. While Dr. Abreu knew Dr. Gumer was signing charts without reading them,
    this Court explained that this evidence about chart signing “does not support an
    inference that Dr. Abreu knew that the patients were ineligible, that they had not
    received partial hospitalization services, or that Dr. Gumer had not treated the
    patients.” Id. at 1309. The government’s circumstantial evidence against
    Dr. Abreu was weak, and her conduct was isolated and peripheral at best. It pales
    compared to the overwhelming evidence showing Abovyan’s role and conduct that
    was central to the criminal conspiracy and its success, his consistent and ongoing
    participation in the scheme throughout his tenure as medical director, and his
    significant financial gains from the scheme.
    Similarly, in Ganji, the Fifth Circuit reversed the healthcare fraud conspiracy
    conviction of a physician serving as the medical director of a home healthcare
    agency. 880 F.3d at 763–64. The evidence was only that: (1) another doctor,
    Dr. Winston Murray, who previously held a similar position, defrauded Medicare;
    (2) when Dr. Ganji accepted the job, she received a monthly check of $1,000; and
    (3) Dr. Ganji’s referral of patients to the agency increased after she became
    medical director. Id. at 771. No evidence supported any inference that Dr. Ganji
    acted in the same fraudulent manner as Dr. Murray. Id. Dr. Ganji’s increase in
    28
    USCA11 Case: 19-10676       Date Filed: 02/22/2021    Page: 29 of 51
    referrals was not nefarious; rather, her patients simply followed her when she
    became affiliated with the home healthcare agency. Id. at 773. And Dr. Ganji
    “provided testimony of her innocence that went unanswered by the [g]overnment,”
    including her explanation that certain blank sheets she signed were bundled with
    other documents she reviewed. Id. at 771. The Fifth Circuit emphasized that
    “[t]he trial record rebut[ted] the [g]overnment’s theory.” Id. at 772.
    Again, in stark contrast, the government’s evidence here was powerful and
    showed Abovyan’s key role, conduct, and participation in the healthcare fraud
    scheme. Abovyan knew he pre-signed all the prescription pads, signed the
    standing orders for excessive lab testing, was not seeing or following up with
    patients at the Facilities, was not doing or revising individualized treatment plans,
    gave his log-in credentials to his nurses, and did not have the required training and
    X Number to prescribe Suboxone. Abovyan even admitted that he was paid “easy
    money” for “Chatman [to] use [Abovyan’s] medical license to bill insurance.”
    Given our extensive record review recounted above, we readily conclude that the
    government’s evidence sufficiently supported Abovyan’s conviction for conspiracy
    to commit healthcare fraud.
    B. The Controlled Substances Act Counts (Counts Two through Nine)
    Counts Two through Nine involve the conspiracy and substantive counts as
    to the buprenorphine prescriptions. Abovyan argues that the government failed to
    29
    USCA11 Case: 19-10676        Date Filed: 02/22/2021    Page: 30 of 51
    prove his buprenorphine prescriptions were not for a legitimate medical purpose or
    were outside the scope of professional practice.
    Under the Controlled Substances Act, it is unlawful, except as otherwise
    authorized, “for any person knowingly or intentionally . . . to manufacture,
    distribute, or dispense . . . a controlled substance.” 
    21 U.S.C. § 841
    (a)(1); see also
    
    21 U.S.C. § 846
     (making it unlawful to conspire to violate § 841). An unlawful
    distribution occurs in the medical context when “1) the prescription was not for a
    legitimate medical purpose or 2) the prescription was not made in the usual course
    of professional practice.” United States v. Joseph, 
    709 F.3d 1082
    , 1102 (11th Cir.
    2013) (quotation marks omitted). The rule is disjunctive, and a doctor violates the
    law if he falls short of either requirement. See Ruan, 966 F.3d at 1172. “The
    appropriate focus is not on the subjective intent of the doctor, but rather it rests
    upon whether the physician prescribes medicine in accordance with a standard of
    medical practice generally recognized and accepted in the United States.” United
    States v. Merrill, 
    513 F.3d 1293
    , 1306 (11th Cir. 2008) (quotation marks omitted).
    Here, Abovyan violated 
    21 U.S.C. § 823
    (g) when he prescribed
    buprenorphine without an X Number. See 
    21 U.S.C. § 823
    (g)(2)(E)(i). We agree
    with Abovyan that this is not a per se violation of § 841(a), and, more importantly,
    this alone does not support a § 841(a) conviction. However, as Dr. Clark testified,
    Abovyan’s lack of an X Number was not the only problem with his buprenorphine
    30
    USCA11 Case: 19-10676       Date Filed: 02/22/2021    Page: 31 of 51
    prescriptions. Abovyan prescribed buprenorphine for pain/withdrawal when
    patients did not have pain/withdrawal. Further, he provided no medical addiction
    treatment and, without accompanying treatment, Abovyan’s buprenorphine
    prescriptions did not serve a legitimate medical purpose.
    Dr. Clark explained that buprenorphine can be a very effective drug when
    used in addiction treatment, but she unequivocally stated that Abovyan’s patients
    were not actually being treated. Prescribing buprenorphine to drug addicts without
    more is not medical treatment. Viewing the evidence in the light most favorable to
    the government, Abovyan prescribed buprenorphine after conducting no physical
    examinations or only a cursory physical examination, having no doctor–patient
    relationship, and making no assessment or treatment plan. Abovyan generally
    delegated the prescribing of buprenorphine to his nurse practitioners,
    inappropriately giving them blank prescription pads and access to his log-in
    credentials for patients’ electronic medical records. When many patients he was
    supposedly “treating” with buprenorphine failed subsequent drug tests, he did
    nothing. Patients rarely even saw their test results. Dr. Clark testified that
    Abovyan’s use of buprenorphine deviated from professional standards of medical
    addiction treatment, and the prescriptions were “not for a legitimate medical
    purpose.”
    Thus, setting aside the X Number issue, Abovyan either prescribed
    31
    USCA11 Case: 19-10676       Date Filed: 02/22/2021    Page: 32 of 51
    buprenorphine for “pain/withdrawal” to patients who were not experiencing pain
    or withdrawal, or he prescribed it to “treat addiction” without actually treating
    addiction. Either way, under the particular circumstances here, the prescriptions
    did not serve a legitimate medical purpose and were not done in the usual course of
    professional practice.
    Our decision in United States v. Joseph, 
    709 F.3d 1082
    , is instructive. In
    Joseph, Spurgeon Green Jr., a physician, and Dorothy Mack, a physician’s
    assistant, were convicted under § 841(a). Id. at 1087–88. They conceded their
    federal-regulation violation by not properly dating and signing the prescriptions.
    Id. at 1102. Mack admitted that she, as a physician’s assistant, lacked the authority
    to write prescriptions for Schedule II substances under Georgia law. Id. This
    Court agreed that their violation of the federal regulation did not constitute a per se
    violation of § 841(a). Id. Nonetheless, “the jury was entitled to infer, based on
    Green’s pre-signing and pre-dating of the prescriptions and Mack’s delivery of
    those prescriptions to Green’s patients, that they violated [§ 841(a)].” Id. We
    observed that “a physician’s delivery of a prescription without conducting any
    physical examination of the patient provides strong evidence to support a
    conviction under [§ 841(a)].” Id.
    Here, Abovyan violated federal law by prescribing a drug, buprenorphine,
    without the required training, licensing, and X Number. Although this does not
    32
    USCA11 Case: 19-10676        Date Filed: 02/22/2021      Page: 33 of 51
    constitute a per se violation of § 841(a), “the jury was entitled to infer” that
    Abovyan violated § 841(a) based on all of his conduct described above, including
    how Abovyan was not actually treating his patients for their addiction. See id.
    We also reject Abovyan’s claim that the prescriptions, nonetheless, served a
    legitimate medical purpose because “these patients were addicts who needed [the]
    buprenorphine that Dr. Abovyan prescribed.” The question is not whether a doctor
    could prescribe buprenorphine for legitimate medical addiction treatment actually
    being rendered, but whether Abovyan himself did prescribe buprenorphine for such
    actual addiction treatment. Based on the cumulative evidence about the patients
    and these prescriptions, a jury could reasonably find that Abovyan was not legally
    prescribing buprenorphine, especially given that the addicts were not being treated,
    were failing drug tests, were not in withdrawal or pain, and were not being seen by
    him.11 Therefore, we conclude sufficient evidence supported Abovyan’s
    convictions on Counts Two through Nine.12
    11
    For example, the jury could infer from the evidence that Abovyan’s buprenorphine
    prescriptions were intended mainly as window-dressing so that the Facilities appeared to be
    providing drug “treatment” when their real purpose was to conduct expensive and unnecessary
    tests on the patients that could be billed to their insurance.
    12
    To the extent Abovyan argues that he did not know about or join a conspiracy to
    unlawfully dispense buprenorphine (Count Two), his argument fails for the same reasons it fails
    as to the conspiracy element in Count One. Abovyan’s prescribing of buprenorphine was part of
    the overall healthcare fraud scheme that Abovyan knew about and joined. Chatman told
    Abovyan that he should prescribe buprenorphine; the prescriptions were part of the purported
    “treatment” that the Facilities billed to insurance but were not really providing.
    33
    USCA11 Case: 19-10676           Date Filed: 02/22/2021         Page: 34 of 51
    IV. JURY INSTRUCTIONS
    Abovyan also challenges various jury instructions, which we discuss in turn.
    A. Instructions as to Count One
    On appeal, Abovyan argues for the first time that the district court plainly
    erred in failing to instruct the jury on the elements of substantive healthcare fraud,
    which was the object of the healthcare fraud conspiracy charge in Count One.
    Abovyan did not object to this omission in the instructions, and plain-error review
    applies. See United States v. Benjamin, 
    958 F.3d 1124
    , 1133 (11th Cir.), cert.
    denied, __ U.S. __, 
    141 S. Ct. 561
     (2020).13
    The district court adequately instructed the jury as to the elements of a
    criminal conspiracy and that its object was healthcare fraud. For example, the
    district court instructed that the jury had to find Abovyan “agreed to try to
    accomplish a common and unlawful plan to commit health care fraud, as charged
    in the superseding indictment” and that, knowing “the unlawful purpose of the
    plan,” he “willfully joined in it.” In turn, the unlawful purpose of the conspiracy,
    as described in the superseding indictment, was that Abovyan conspired to: “(a)
    defraud health care benefit programs . . . ; and (b) obtain, by means of materially
    13
    Plain error requires (1) error, (2) that is plain, and (3) that affects substantial rights.
    Benjamin, 958 F.3d at 1133. But even if all these elements exist, this Court may exercise its
    discretion to correct the error only if such error seriously affects the fairness, integrity, or public
    reputation of the judicial proceedings. Id. We reject the government’s contention that defense
    counsel invited the error.
    34
    USCA11 Case: 19-10676        Date Filed: 02/22/2021      Page: 35 of 51
    false and fraudulent pretenses, representations, and promises, any of the money
    and property owned by, and under the custody and control of, health care benefit
    programs . . . .” Superseding Indictment at 9 (emphasis added). The district court,
    itself, however, did not expressly instruct the jury as to the elements of a healthcare
    fraud offense.
    The Supreme Court has explained that “an instruction that omits an element
    of the offense does not necessarily render a criminal trial fundamentally unfair or
    an unreliable vehicle for determining guilt or innocence.” Neder v. United States,
    
    527 U.S. 1
    , 9, 
    119 S. Ct. 1827
    , 1833 (1999). Although such an omission may
    constitute plain error, that is not always the case. See United States v. Musgrave,
    
    444 F.2d 755
    , 764 (5th Cir. 1971) (“[T]he trial judge’s failure here to instruct the
    jury on all the essential elements of the crimes in counts two and four, even though
    not requested, [is] plain error.”) 14; United States v. Hensel, 
    711 F.2d 1000
    , 1005
    (11th Cir. 1983) (“Musgrave does not hold that every failure to charge on all the
    essential elements of the crime results in plain error.”).
    In United States v. Gonzalez, the defendant argued that the district court
    plainly erred by failing to instruct the jury on the elements required to prove a
    violation of the federal anti-kickback statute, which was one of the objects of the
    14
    In Bonner v. City of Prichard, 
    661 F.2d 1206
    , 1209 (11th Cir. 1981) (en banc), this
    Court adopted as precedent the decisions of the former Fifth Circuit handed down prior to
    October 1, 1981.
    35
    USCA11 Case: 19-10676         Date Filed: 02/22/2021   Page: 36 of 51
    conspiracy. 
    834 F.3d 1206
    , 1225 (11th Cir. 2016). We held that the failure to
    explain the term “kickback” was not “a clear or obvious error.” 
    Id.
     One reason
    was because “the indictment essentially quoted the entire relevant portion of the
    anti-kickback statute.” 
    Id. at 1226
    .
    Similarly, here the district court referred to an “unlawful plan to commit
    health care fraud, as charged in the superseding indictment.” The jury had a
    redacted copy of the superseding indictment, which incorporated the statutory
    elements of healthcare fraud into the conspiracy charge. See 
    18 U.S.C. § 1347
    (a).
    The superseding indictment described healthcare fraud as a scheme to both
    “(a) defraud health care benefit programs . . . ; and (b) obtain, by means of
    materially false and fraudulent pretenses . . . any of the money and property owned
    by . . . health care benefit programs,” which tracks almost verbatim the language of
    
    18 U.S.C. § 1347
    (a)(1) and (2). Superseding Indictment at 9 (emphasis added). If
    anything, the description in the superseding indictment required more than the
    statute, which only requires proof of one of those two elements. See 
    18 U.S.C. § 1347
    (a)(1)–(2).
    Moreover, in this particular case, there was no dispute that there was a
    healthcare fraud conspiracy and its object—healthcare fraud—did occur. Even if it
    was plain error, the omission of the elements of healthcare fraud from the
    instructions did not affect Abovyan’s substantial rights. See Benjamin, 958 F.3d at
    36
    USCA11 Case: 19-10676        Date Filed: 02/22/2021    Page: 37 of 51
    1133. Abovyan’s theory of defense acknowledged that there was a healthcare
    fraud scheme but asserted that he was merely an “unwitting patsy.” By the time of
    Abovyan’s trial, numerous people were already convicted for their involvement in
    Chatman’s healthcare fraud scheme at the Facilities, and three of them testified in
    Abovyan’s trial. Abovyan argued solely that he was unaware of any conspiracy
    and did not agree to join it. Under the actual circumstances of this case, any error
    in failing to explain the elements of the substantive healthcare fraud did not affect
    Abovyan’s substantial rights, given the jury charge, the superseding indictment,
    and that all parties agreed the substantive offense had been committed by others at
    the Facilities. See Gonzalez, 834 F.3d at 1225 (“[I]n reviewing jury instructions,
    our task is also to view the charge itself as part of the whole trial.” (quotation
    marks omitted)).
    B. Denial of Abovyan’s Requested Instruction
    Next, Abovyan argues that, as to Counts Two through Nine, the district court
    abused its discretion by declining to give his requested instruction on the
    difference between criminal and civil liability. We review for an abuse of
    discretion a refusal of the district court to give a requested jury instruction. Joseph,
    709 F.3d at 1093. “When we review the refusal to give an instruction for abuse of
    discretion, we ask whether the requested instruction is correct, not adequately
    covered by the charge given, and involves a point so important that failure to give
    37
    USCA11 Case: 19-10676       Date Filed: 02/22/2021    Page: 38 of 51
    the instruction seriously impaired the party’s ability to present an effective case.”
    United States v. Duperval, 
    777 F.3d 1324
    , 1334 (11th Cir. 2015) (quotation marks
    omitted).
    The district court did not abuse its discretion in refusing to give Abovyan’s
    requested instruction because it was not a correct statement of the law. Abovyan’s
    proposed instruction stated, among other things: “the [g]overnment must prove
    beyond a reasonable doubt that Dr. Abovyan was not acting as a doctor but as a
    drug dealer,” that “[t]he essential issue for your determination is whether
    Dr. Abovyan acted not as a doctor, or even as a bad doctor, but as a ‘pusher,’” and
    that he was engaged in criminal activity, like “knowingly selling narcotics to a
    ‘patient’ who was not really sick but wanted drugs for recreational purposes.”
    Contrary to Abovyan’s proposed instruction, and as explained above, the law
    requires only that the jury find the doctor prescribed a drug “not for a legitimate
    medical purpose” or not “in the usual course of professional practice.” See Ruan,
    966 F.3d at 1136 (quotation marks omitted). The district court properly declined to
    give Abovyan’s proposed instruction.
    C. Instructions as to X Number
    Abovyan also argues that the instructions created strict § 841(a) liability for
    the violation of § 823(g), which contains the licensing requirement for an
    X Number. We review de novo whether a given jury instruction misstated the law.
    38
    USCA11 Case: 19-10676       Date Filed: 02/22/2021    Page: 39 of 51
    United States v. Melgen, 
    967 F.3d 1250
    , 1259 (11th Cir. 2020). “[W]e will reverse
    a conviction due to an erroneous jury instruction only when ‘the issues of law were
    presented inaccurately, or the charge improperly guided the jury in such a
    substantial way as to violate due process.’” Gonzalez, 834 F.3d at 1222 (quoting
    United States v. Williams, 
    526 F.3d 1312
    , 1320 (11th Cir. 2008)). “We must have
    ‘a substantial and ineradicable doubt as to whether the jury was properly guided in
    its deliberations’ before reversing a conviction on a challenge to the jury charge.”
    United States v. Joyner, 
    882 F.3d 1369
    , 1375 (11th Cir. 2018) (quoting United
    States v. House, 
    684 F.3d 1173
    , 1196 (11th Cir. 2012)).
    The jury instructions accurately stated the law. First, the district court
    correctly described the elements of a § 841(a) violation. The district court
    explained that Abovyan was guilty under § 841(a) if the government proved
    beyond a reasonable doubt that he “dispensed . . . not for a legitimate medical
    purpose or outside the usual course of professional practice, the controlled
    substance, as charged.” The instructions charged that § 841(a) has a mens rea of
    “knowingly and intentionally” and that Abovyan cannot “knowingly” do
    something “because of a mistake or by accident.”
    Second, appearing to reference 
    21 C.F.R. § 1306.05
    , the district court
    properly instructed that prescriptions must “be dated as of, and signed on, the day
    when issued” and that “the prescribing practitioner is responsible in case the
    39
    USCA11 Case: 19-10676    Date Filed: 02/22/2021    Page: 40 of 51
    prescription does not conform in all essential aspects to the law and regulations.”
    Third, the district court precisely recited the X Number requirement in
    § 823(g), the process to obtain it, and the consequences for non-compliance, as
    follows:
    [I]n order to prescribe buprenorphine for detoxification and
    maintenance treatment, a practitioner is required to obtain a waiver
    under the Drug Addiction Treatment Act of 2000. The practitioner
    must apply to the Substance Abuse and Mental Health Services
    Administration (“SAMHSA”), under the Secretary of Health and
    Human Services, who verifies that the practitioner meets the
    requirements, including completion of not less than eight hours of a
    qualified training course by the physician. After SAMHSA notifies the
    Drug Enforcement Administration (“DEA”) that the requirements have
    been met, DEA then assigns the practitioner a special registration
    number, known as a “DEA X-number.” If a practitioner is in violation
    of these conditions and dispenses buprenorphine for maintenance
    treatment or detoxification treatment, the Attorney General may
    consider the practitioner to have committed an act that renders the
    registration of the practitioner pursuant to subsection (f) to be
    inconsistent with the public interest.
    A prescription for buprenorphine for “detoxification treatment”
    or “maintenance treatment” must include the practitioner’s DEA X-
    number.
    Fourth, the instructions well explained “the usual course of professional
    practice,” as follows:
    A controlled substance is prescribed by a physician in the usual course
    of professional practice and, therefore, lawfully, if the substance is
    prescribed by him as part of his or her medical treatment for the patient
    in accordance with the standards of medical practice generally
    recognized and accepted in the United States. The appropriate standard
    of care is based on the knowledge, circumstances and standards that are
    recognized as acceptable and appropriate at the time the physician
    40
    USCA11 Case: 19-10676         Date Filed: 02/22/2021        Page: 41 of 51
    acted. The fact that bad results follow treatment rendered by a
    physician does not, in itself, mean that the physician’s conduct fell
    below the appropriate standard of care.
    Finally, the instructions rightly reiterated that, to convict Abovyan for
    violating § 841(a), the government had to prove that his “actions were not for
    legitimate medical purposes or were outside the usual course of professional
    practice.”
    At no point did the district court instruct the jury that a violation of the
    X Number-licensing requirement necessitated a finding of guilt on Counts Two
    through Nine. As discussed above, we agree that a violation of § 823(g) is not a
    per se violation of § 841(a). And the district court here did not instruct the jury
    that it was. We thus conclude that these instructions, considered as a whole, did
    not create strict § 841(a) liability for the violation of the X Number license
    requirement.15 Because the issues of law were presented accurately to the jury,
    there was no error.16 See Gonzalez, 834 F.3d at 1222.
    15
    We recognize that, at the charge conference, the district court and the government made
    some statements that seemed to suggest Abovyan’s alleged violation of § 823(g) made him
    “strict[ly] liab[le]” under § 841(a). But the instructions themselves did not charge that. Further,
    to the extent that Abovyan contends that the refusal to give his requested instruction, combined
    with the above instructions actually given, resulted in reversible error, we disagree because the
    district court did not err in either instance.
    16
    Abovyan also challenges two evidentiary rulings during his trial. He claims that the
    district court abused its discretion in admitting evidence of Abovyan’s gambling hobby and in
    improperly limiting cross-examination of the government’s case agent. We conclude that these
    claims wholly lack merit and do not warrant further discussion.
    41
    USCA11 Case: 19-10676        Date Filed: 02/22/2021   Page: 42 of 51
    V. SENTENCES
    Abovyan also challenges his sentences. We review how the district court
    calculated Abovyan’s advisory guidelines range and then his claims on appeal.
    A. Guidelines Calculation
    The presentence investigation report (“PSI”) determined that, during
    Abovyan’s five-month employment at Reflections, 42 insurers were billed a total
    of $11,345,741.55, from which Reflections received $1,058,097.88 in
    reimbursements, and Abovyan was responsible for the intended loss of
    $11,345,741.55.
    For Count One, the PSI calculated an offense level of 32, consisting of: (1) a
    base offense level of 6, under U.S.S.G. § 2B1.1(a)(2); (2) a 20-level increase based
    on an intended loss of between $9.5 million and $25 million, under
    § 2B1.1(b)(1)(K); (3) a 2-level increase because the offense involved more than ten
    victims, under § 2B1.1(b)(2)(A); (4) a 2-level increase, under § 3A1.1(b)(1),
    because Abovyan knew or should have known the victims were vulnerable; and (5)
    a 2-level increase, under § 3B1.3, because Abovyan used his skill as a medical
    doctor to facilitate the offense.
    For Counts Two through Nine, the PSI used the base offense level of 24
    because the offense involved a drug equivalency of between 100 and 400
    kilograms of marijuana. See U.S.S.G. § 2D1.1(a)(5) and (c)(8).
    42
    USCA11 Case: 19-10676       Date Filed: 02/22/2021   Page: 43 of 51
    After making the multiple-count adjustment under § 3D1.4(a)–(c), the PSI
    recommended a combined adjusted offense level of 33. Based on an offense level
    of 33 and a criminal history category of I, Abovyan’s advisory guidelines range
    was 135 to 168 months’ imprisonment.
    Abovyan objected to the PSI’s use of intended loss, instead of actual loss, to
    calculate his advisory guidelines range. He acknowledged that the Sentencing
    Guidelines define loss as the greater of actual or intended loss. See U.S.S.G.
    § 2B1.1 cmt. n.3(A). Here, the amount that Abovyan helped the Facilities and labs
    bill to the insurance companies was approximately $11.3 million (intended loss),
    but the insurance companies only reimbursed approximately $1 million (actual
    loss).
    Abovyan argued that the use of the higher intended loss would cause an
    unwarranted disparity among similarly situated defendants. His codefendant
    Barbuto was held accountable only for the actual loss, as stipulated in her plea
    agreement. The PSI also referenced other co-conspirators’ convictions; they pled
    guilty too, and their sentences were based on actual loss.
    At the sentencing hearing, the district court overruled Abovyan’s objection
    and used the intended loss amount. The district court adopted the PSI’s findings
    and guidelines calculations and sentenced Abovyan to 120 months’ imprisonment
    on his Counts One through Eight convictions, to run concurrently, and a
    43
    USCA11 Case: 19-10676         Date Filed: 02/22/2021        Page: 44 of 51
    consecutive 15-month sentence on his Count Nine conviction.
    B. Sentencing Disparity Argument
    Abovyan argues that the district court erred in calculating his advisory
    guidelines range based on intended loss, instead of actual loss. Because actual loss
    was the basis for his codefendant and his other co-conspirators’ sentences,
    Abovyan contends the district court created an unwarranted sentencing disparity by
    using the higher intended loss to calculate his guidelines range. 17
    First, there is no guidelines-calculation error. The guidelines define loss as
    the greater of actual or intended loss. See U.S.S.G. § 2B1.1 cmt. n.3(A). The
    district court correctly used the intended loss here because it was greater than the
    actual loss. See id.
    Second, the essence of Abovyan’s argument is more that there is an
    unwarranted sentencing disparity, which addresses the reasonableness of the
    sentences. In imposing a sentence, district courts must consider several factors,
    including the need “to avoid unwarranted sentence disparities among defendants
    with similar records who have been found guilty of similar conduct.” 
    18 U.S.C. § 3553
    (a)(6). “[D]efendants who cooperate with the government and enter a
    17
    “This Court reviews de novo the District Court’s interpretation of the guidelines and its
    application of the guidelines to the facts.” United States v. Fox, 
    926 F.3d 1275
    , 1278 (11th Cir.),
    cert. denied, __ U.S. __, 
    140 S. Ct. 639
     (2019). We review the reasonableness of a sentence for
    abuse of discretion. Williams, 
    526 F.3d at 1321
    .
    44
    USCA11 Case: 19-10676         Date Filed: 02/22/2021      Page: 45 of 51
    written plea agreement are not similarly situated to a defendant who provides no
    assistance to the government and proceeds to trial.” United States v. Docampo,
    
    573 F.3d 1091
    , 1101 (11th Cir. 2009); see also United States v. Jayyousi, 
    657 F.3d 1085
    , 1117–18 (11th Cir. 2011). “There is no unwarranted disparity even when
    the sentence the cooperating defendant receives is substantially shorter.”
    Docampo, 
    573 F.3d at 1101
     (quotation marks omitted).
    Because codefendant Barbuto and the other co-conspirators involved in the
    fraud scheme all pled guilty and their plea agreements provided for how loss was
    to be determined, those defendants are not “similarly situated” to Abovyan. See 
    id.
    Therefore, any disparity between the sentences of Abovyan and them is not an
    “unwarranted” sentence disparity within the meaning of § 3553(a)(6), much less
    one that required the district court to impose a lower sentence regardless of the
    other § 3553(a) factors. See 
    18 U.S.C. § 3553
    (a) (requiring the district court to
    consider multiple factors, only one of which is the need to avoid unwarranted
    sentence disparities, in choosing the appropriate sentence). 18 The district court did
    18
    To the extent Abovyan argues that the district court’s use of intended loss was
    unconstitutional because it unfairly penalized him for going to trial, his argument is meritless.
    See Frank v. Blackburn, 
    646 F.2d 873
    , 882–83 (5th Cir. 1980) (en banc), modified on other
    grounds, 
    646 F.2d 902
     (5th Cir. 1981) (en banc) (explaining that “the mere imposition of a
    longer sentence than defendant would have received had he pleaded guilty” is not automatically
    unconstitutional punishment). Further, Abovyan does not point to any evidence that the district
    court imposed a sentence within the correctly calculated advisory guidelines range to punish him
    for exercising his right to go to trial.
    45
    USCA11 Case: 19-10676         Date Filed: 02/22/2021       Page: 46 of 51
    not err in calculating Abovyan’s advisory guidelines range or abuse its discretion
    in sentencing him.
    C. Loss Amount and Foreseeability
    Abovyan also argues that the district court erred in determining the amount
    of the intended loss because it was not supported by a preponderance of the
    evidence. He asserts that the district court failed to make underlying findings as to
    the scope of the criminal activity that Abovyan agreed to undertake and the
    reasonable foreseeability of the loss amount attributed to him. 19
    Abovyan waived these arguments because he did not object to the amount of
    the intended loss in the PSI or its foreseeability and, instead, repeatedly told the
    court that he challenged only the use of intended instead of actual loss.20 See
    United States v. Bennett, 
    472 F.3d 825
    , 832 (11th Cir. 2006) (“[C]hallenges to the
    facts contained in the PSI must be asserted with specificity and clarity. Otherwise,
    the objection is waived.” (citation omitted)); United States v. Wade, 
    458 F.3d 1273
    , 1277 (11th Cir. 2006) (“It is the law of this circuit that a failure to object to
    19
    “We review a district court’s determination of the loss amount under the Sentencing
    Guidelines for clear error.” Melgen, 967 F.3d at 1265. “Because the district court is in a unique
    position to assess the evidence and estimate the loss based upon that evidence, its loss
    determination is entitled to appropriate deference.” Id. (citing U.S.S.G. § 2B1.1 cmt. n.3(C)).
    20
    Although Abovyan suggested at one point that the loss amount was “not reasonably
    foreseeable” for him, he then clarified that he “agree[d] with the numbers” but objected to using
    the intended loss amount.
    46
    USCA11 Case: 19-10676        Date Filed: 02/22/2021    Page: 47 of 51
    allegations of fact in a PSI admits those facts for sentencing purposes.”).
    In any event, Abovyan’s arguments are meritless. Under the Sentencing
    Guidelines, a defendant’s offense level shall be adjusted based on the reasonably
    foreseeable activity of co-conspirators that is within the scope of and in furtherance
    of the conspiracy. U.S.S.G. § 1B1.3(a)(1)(B). “[T]o determine a defendant’s
    liability for the acts of others, the district court must first make individualized
    findings concerning the scope of criminal activity undertaken by a particular
    defendant.” United States v. Hunter, 
    323 F.3d 1314
    , 1319 (11th Cir. 2003)
    (quotation marks omitted). The district court may determine reasonable
    foreseeability only after it makes those individualized findings. 
    Id.
     However, this
    Court will not vacate a defendant’s sentence based on the district court’s failure to
    make specific findings “[i]f the record otherwise supports the court’s
    determination.” United States v. Baldwin, 
    774 F.3d 711
    , 727 (11th Cir. 2014).
    At sentencing, the government presented testimony of an Internal Revenue
    Service special agent, who prepared a “loss amount” chart based on records from
    insurance companies and the Facilities. The billing information contained in the
    chart concerned only the period that Abovyan worked at the Facilities. The chart
    showed that the Facilities billed a total of $1,892,273.15 to seven insurance
    companies for treatment services, but the chart did not include amounts billed to
    the other defrauded insurance companies. The chart showed that Smart Lab billed
    47
    USCA11 Case: 19-10676       Date Filed: 02/22/2021    Page: 48 of 51
    $9,453,468.40 to insurance, but the chart did not include amounts billed by other
    labs, like Ally. Based on those limited numbers alone, the chart calculated that
    insurance companies were billed a total of $11,345,741.55.
    After the special agent’s testimony, the district court found that (1) the loss
    amounts presented by the government relate only to the time when Abovyan was
    there and are actually conservative in terms of total billings, and (2) the
    $11.3 million figure accurately reflects the loss amount.
    The record supports the district court’s findings. As medical director,
    Abovyan authorized the Facilities’ urine testing protocol and signed standing
    consent orders that allowed the Facilities to send urine samples out for lab testing
    at least two to three times per week. He pre-signed Ally requisition forms knowing
    that they would be filled in and copied by Facilities employees. He approved any
    outstanding orders by Dr. Tendler. Abovyan admitted that the Facilities would
    “test for everything,” meaning full panels of tests on each sample, and he reviewed
    and electronically signed the test results. Abovyan knew that the Facilities were
    billing insurance for patient “treatment,” as he admitted that Chatman paid him to
    “use his medical license to bill insurance.” Given Abovyan’s key role in the
    healthcare fraud scheme, the amounts billed to the insurance companies were
    reasonably foreseeable to him. Plus, as the district court noted, the $11.3 million
    figure is conservative because it does not include the amounts billed by toxicology
    48
    USCA11 Case: 19-10676        Date Filed: 02/22/2021     Page: 49 of 51
    labs other than Smart Lab, like Ally, and only includes amounts billed by the
    Facilities to a subset of the 42 defrauded insurance companies. See Melgen, 967
    F.3d at 1265 (“[T]he district court need only reach a reasonable estimate of loss.”).
    Therefore, the district court did not clearly err in reaching its loss findings.
    D. Count Two Statutory Penalty
    Finally, Abovyan argues that his Count Two sentence exceeds the statutory
    maximum penalty. Count Two alleged that Abovyan conspired to distribute
    controlled substances spanning Schedules II, III, and IV, each of which carries a
    different statutory maximum penalty. Generally, the statutory maximum penalty
    for a Schedule II drug is 20 years, a Schedule III drug is 10 years, and a Schedule
    IV drug is 5 years. 
    21 U.S.C. § 841
    (b)(1)(C), (b)(1)(E), (b)(2). The jury rendered
    a general guilty verdict for the Count Two conspiracy offense and did not specify
    which substance was involved.
    The government conceded for sentencing purposes that, because the jury did
    not make a specific drug-type finding, Abovyan’s statutory maximum penalty
    should not exceed the penalty for conspiring to dispense the Schedule III
    buprenorphine involved in Counts Three through Nine. On appeal, Abovyan
    contends that, due to the ambiguity, he should receive the most lenient statutory
    49
    USCA11 Case: 19-10676         Date Filed: 02/22/2021        Page: 50 of 51
    maximum penalty of 5 years (Schedule IV). 21
    Because Abovyan did not raise this objection at the sentencing hearing, we
    review for plain error. See United States v. Deason, 
    965 F.3d 1252
    , 1265 (11th
    Cir. 2020). In United States v. Candelario, 
    240 F.3d 1300
     (11th Cir. 2001), the
    defendant was convicted of conspiring to traffic, and possessing with intent to
    distribute, crack cocaine. 
    Id. at 1303
    . During the trial, Candelario’s codefendant
    testified that, as part of the conspiracy, Candelario sold him nine ounces of crack
    cocaine for distribution. 
    Id. at 1303, 1312
    . The jury, however, did not find the
    drug quantity as to either Candelario’s substantive or conspiracy convictions. See
    
    id.
     at 1311–12. Despite the district court’s plain error, we declined to vacate the
    defendant’s conspiracy sentence because “Count One of the indictment, the
    conspiracy count, necessarily subsumes the amount of cocaine in the possession
    charge.” 
    Id. at 1312
    . “Because the jury found at least nine ounces of crack
    cocaine in the possession charge, the jury also must have determined that at least
    nine ounces were involved in the conspiracy.” 
    Id.
    The same principle is applied here. It is plain error for a district court to
    “sentence a defendant beyond the maximum sentence for the least serious
    21
    Abovyan also contends, in a passing statement in his brief, that his total sentence should
    not have exceeded 10 years, but he does not explain why or cite any law in support.
    Accordingly, we deem that issue abandoned. See United States v. Jernigan, 
    341 F.3d 1273
    , 1283
    n.8 (11th Cir. 2003).
    50
    USCA11 Case: 19-10676       Date Filed: 02/22/2021   Page: 51 of 51
    substance charged in a multi-object drug conspiracy” “in the absence of a special
    verdict.” United States v. Grow, 
    977 F.3d 1310
    , 1330–31 (11th Cir. 2020)
    (quotation marks omitted). But like in Candelario, this error did not affect
    Abovyan’s substantial rights. Because the jury returned convictions for seven
    substantive counts of unlawful distribution of buprenorphine, a Schedule III drug,
    it “also must have determined” that buprenorphine was involved in the conspiracy
    to distribute a controlled substance, permitting a statutory penalty of 10 years on
    Count Two. See Candelario, 
    240 F.3d at 1312
    ; 
    21 U.S.C. § 841
    (b)(1)(E); 
    21 C.F.R. § 1308.13
    (e)(2)(i).
    VI. CONCLUSION
    For the foregoing reasons, we affirm Abovyan’s convictions and sentences.
    AFFIRMED.
    51