United States v. Gerard M DiLeo , 625 F. App'x 464 ( 2015 )


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  •                Case: 13-10661       Date Filed: 09/01/2015      Page: 1 of 47
    [DO NOT PUBLISH]
    IN THE UNITED STATES COURT OF APPEALS
    FOR THE ELEVENTH CIRCUIT
    ________________________
    No. 13-10661
    ________________________
    D.C. Docket No. 3:10-cr-00101-MCR-2
    UNITED STATES OF AMERICA,
    Plaintiff-Appellee,
    versus
    GERARD M. DILEO,
    DENNIS M. CARONI,
    JOSEPH GEORGE PASTOREK, II,
    Defendants-Appellants.
    ________________________
    Appeals from the United States District Court
    for the Northern District of Florida
    ________________________
    (September 1, 2015)
    Before MARTIN and ANDERSON, Circuit Judges, and COTE, District Judge.
    ___________
    *      Honorable Denise Cote, United States District Judge for the Southern District of New
    York, sitting by designation.
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    PER CURIAM:
    In September 2010, a federal grand jury charged Dennis Caroni, Gerard M.
    DiLeo, Theodore G. Aufdemorte, Jr., 1 and Joseph George Pastorek, II, with one
    count of conspiracy to distribute drugs and one count of conspiracy to commit
    money laundering. The indictment charged that DiLeo and Pastorek were
    physicians licensed by the state of Louisiana with the authority to prescribe
    controlled substances in Schedules II through V. Using Caroni and Aufdemorte’s
    company, Global Pain Management, LLC (“Global Pain”), the four codefendants
    allegedly conspired to unlawfully prescribe Schedule II and III controlled
    substances through prescription practices done outside the usual course of medical
    practice and for other than legitimate medical purposes. The indictment further
    alleged that the offense involved “a mixture and substance containing” multiple
    prescription drugs, and that the drugs had caused at least one death.
    Caroni and Aufdemorte formed Global Pain in January 2004 to operate and
    manage pain management clinics under various names in the New Orleans area. In
    2005, Caroni opened a Global Pain pain management clinic in Pensacola that
    stayed open for approximately two weeks. The DEA began surveilling one of
    Global Pain’s clinics in November 2005 and identified five separate incidents in
    which individuals who had previously been convicted of controlled substances
    1
    The indictment against Aufdemorte was later dismissed.
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    charges visited the clinic. In January and March 2006, two undercover DEA
    agents tried to obtain prescriptions for controlled substances from Global Pain
    without a legitimate medical reason but neither agent was successful.
    In February 2008, the Government obtained search warrants for the offices
    of two of Global Pain’s clinics and for Caroni’s grandmother’s house. A jury trial
    was conducted from October 19, 2011, through November 23, 2011. Dr. Ted
    Parran, a government-retained expert in the field of pain management, addiction
    medicine, and the prescription of controlled substances, reviewed 96 patient files
    that were seized by the government. Dr. Parran opined that the prescription
    practices of Global Pain were dangerous, not consistent with the usual course of
    medical practice, and not for legitimate medical purposes. Another Government
    pain expert witness, Dr. Robin Hamill-Ruth, reviewed files from the Pensacola
    clinic and testified that the prescribing done there was unsafe and outside the usual
    course of medical practice. Dr. Carol Warfield, Caroni’s expert in pain
    management, reviewed the same patient files that Dr. Parran had reviewed. She
    concluded that the pain medications were prescribed to patients for legitimate
    medical reasons and were done so within the accepted standard of care of the
    practice of pain medicine.
    Former office staff testified that follow-up visits at the clinics took an
    average of five minutes per patient. At some point during the conspiracy, patients
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    were able to pay for two two-week prescriptions, with the second prescription post-
    dated, in a single visit; they would pick up the second prescription later, without
    having to see a doctor. Global Pain eventually required patients to make two clinic
    visits per month where the second visit would entail the patients receiving their
    prescriptions after only briefly seeing a doctor. During the week after Hurricane
    Katrina occurred, Global Pain allowed its patients to pick up their prescriptions
    without having to see a doctor or enter the clinic as long as they paid for their
    prescriptions.
    The patient files revealed that Global Pain was aware that several of its
    patients suffered from drug addiction, and some of those patients’ families asked
    Global Pain to not give them access to pain medication. Patients testified that they
    were never examined by a doctor at the clinics even though some of their
    respective files indicated that an examination was performed. Clinic staff testified
    that the exam rooms either contained no examination tables or that the tables were
    not used because they never changed the tables’ paper covering. One of the
    doctors testified that the only physical examination he conducted was to check a
    patient’s heart and lungs with a stethoscope. Patients often appeared to be under
    the influence when they were in the waiting room. Prescriptions were sometimes
    provided despite the doctors stating that the medication was not needed.
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    Global Pain employees testified that patients were charged between $100 to
    $400 per visit based on whether they were receiving Schedule II drugs or Schedule
    III, IV, or V drugs. Caroni called the clinics regularly, though later on he was
    rarely physically present, and he instructed one of his employees to give him daily
    updates of the cash totals. He established a patient referral program where patients
    could earn a free visit if they referred five patients to Global Pain. Caroni told at
    least two employees that what patients did with the prescriptions was not his
    business. One doctor testified that he walked away from Global Pain’s $500,000
    annual salary without any future job prospects because he did not want to be a part
    of a “pill mill.”
    Global Pain did not accept insurance claims, and patients had to pay in cash
    until 2007, at which point it also began accepting some payments by check, money
    order, and credit card. At some point in time, Global Pain’s money was kept at
    Caroni’s grandmother’s house for approximately one month because the clinic did
    not have a bank account. It frequently changed banks because bank managers
    closed the company’s accounts as a result of Caroni’s behavior. Caroni and DiLeo
    opened approximately 57 bank accounts at 15 different banks during the course of
    the conspiracy. Caroni, or other employees on his behalf, deposited large sums of
    cash into the bank accounts almost daily, and sometimes into more than two
    separate bank accounts. Each deposit was always under $10,000 to avoid the
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    reporting requirements. In total, Global Pain deposited approximately $8,557,205
    from January 2004 through December 2007. After a jury trial, Caroni and DiLeo
    were found guilty of both drug and money laundering conspiracies, and Pastorek
    was found guilty of the drug conspiracy. The Defendants raise numerous
    challenges to the judgment of the district court. We address each in turn.
    I. DISCUSSION
    A.    Venue
    DiLeo argues that the Government failed to prove venue and that the district
    court erred when it refused to allow the defense to argue it was missing or submit a
    jury instruction on the issue. 2 The parties stipulated that Pensacola – the location
    of the third clinic that Caroni ran for a short time – was located in the Northern
    District of Florida for venue purposes. Specifically, the parties agreed that “the
    activities within Pensacola, and in Escambia County, that those activities,
    Pensacola and Escambia County are situated within the Northern District of
    Florida for venue purposes.” During the charge conference, the Government
    attorney stated that the Defendants had stipulated to venue while defense counsel
    countered that they had just stipulated that Pensacola was in the Northern District.
    The court suggested that the Defendants were “long past a venue challenge.” After
    reading the stipulation, the court stated that if they were seeking an instruction on
    2
    Both Caroni and Pastorek adopt this argument.
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    venue, they needed to get working on it, because it was not something that had
    ever been presented to her before as an issue and it was really a legal question that
    needed to be decided first and foremost. After the Government attorney stated that
    venue had never been raised before, counsel for one of the Defendants stated that
    he did not realize that it was an issue until now. The Government attorney replied
    that he did not know how the Defendants did not know because he mentioned why
    they were in Florida in his opening statement. The court told defense counsel that
    he should research and prepare something for her because it was not something she
    had anticipated.
    Later that same day, the court told the defense that it could not argue venue
    to the jury and then refused to instruct the jury on venue. At first, she stated that
    they could bring a proposed instruction later but then she scolded the defense for
    not raising it sooner and stated that they could not bring the issue in a proposed
    instruction at all.
    DiLeo argues that the district court committed structural error when it
    prohibited defense counsel from arguing the Government failed to prove venue,
    and reversible error when it refused to give the requested jury instructions on
    venue.3
    3
    The Defendants did not waive this argument by raising it when they did: “when an
    indictment contains a proper allegation of venue so that a defendant has no notice of a defect of
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    We have stated that venue is an essential element in a criminal case and
    should not be treated as a mere technicality. United States v. Snipes, 
    611 F.3d 855
    ,
    865 (11th Cir. 2010). It is guaranteed by the Constitution and a question of fact for
    the jury. 
    Id. at 866.
    We have also stated:
    A conspiracy may be prosecuted in the district where it was formed or
    in any district where an overt act was committed in furtherance of its
    objects. An overt act may be that of only a single one of the
    conspirators and need not be itself a crime. An individual conspirator
    need not participate in the overt act in furtherance of the conspiracy.
    Once a conspiracy is established, and an individual is linked to that
    conspiracy, an overt act committed by any conspirator is sufficient.
    United States v. Schlei, 
    122 F.3d 944
    , 975 (11th Cir. 1997) (internal citations and
    punctuation omitted). Our precedent states that it is reversible error to fail to
    instruct when the defendant requests it and the testimony puts venue at issue.
    United States v. Green, 
    309 F.2d 852
    , 856-57 (5th Cir. 1962).4 We have stated that
    although venue is an essential element, it is not a substantive element, requiring per
    se reversal when instructions are sought but not given. United States v. White, 
    611 F.2d 531
    , 536 (5th Cir. 1980) (holding that no plain error was committed when the
    venue until the Government rests its case, the objection is timely if made at the close of
    evidence.” United States v. Daniels, 
    5 F.3d 495
    , 496 (11th Cir. 1993). Here, the indictment
    alleged venue and thus, Defendants’ objection to venue was timely. Defendants did not waive
    the objection by failing to raise it before trial.
    4
    In Bonner v. City of Prichard, 
    661 F.2d 1206
    , 1209 (11th Cir. 1981)(en banc), this Court
    adopted as binding precedent all of the decisions of the former Fifth Circuit handed down prior
    to the close of business on September 30, 1981.
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    district court failed to instruct on venue). The Supreme Court has held that
    harmless error applies when the trial court fails to instruct on an essential element
    of a crime, Neder v. United States, 
    527 U.S. 1
    , 9, 
    119 S. Ct. 1827
    , 1834 (1999),
    and other courts have held that this specific error should be reviewed for harmless
    error, United States v. Casch, 
    448 F.3d 1115
    , 1117 (9th Cir. 2006). In Casch, the
    court employed a standard that if the evidence that the defendant committed the
    conspiracy in the district where convicted was substantial and uncontroverted, the
    district court’s error was harmless. 
    Id. While the
    district court erred, the evidence of venue was uncontroverted,
    making that error harmless. After the Defendants entered into their conspiracy,
    Caroni, DiLeo, and two others made plans to open the clinic in Pensacola. Caroni
    and DiLeo hired and trained Dr. Klug to be the prescribing physician. The same
    unlawful practices used in New Orleans were carried over to the Pensacola Global
    clinic. When Dr. Klug asked Dr. DiLeo for guidance because of his inexperience
    with respect to pain management, Dr. DiLeo instructed him to just prescribe what
    the patients had previously been receiving. And with respect to physical exams,
    Dr. Klug testified that he merely listened with a stethoscope to the patients’ hearts
    and lungs. Expert Hamill-Ruth testified that Klug’s prescribing was outside of the
    standard of care and inconsistent with the operation of a legal clinic. Caroni
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    opened two bank accounts in Pensacola in the name of the clinic in which money
    from the clinic was deposited.
    Defendants also procured facilities to house the Pensacola clinic and
    operated it for eight days. Defendants sent several employees to either run the
    office or help train those working there. They procured an apartment for one of
    those employees, whom they sent from the office in Covington to work at the new
    clinic. Even though the three Defendants never traveled to the Northern District of
    Florida, it was abundantly clear that it was part of their plan and conspiracy.
    Although there was strong evidence that the activities in Pensacola were in fact
    criminal, venue exists under our case law “in any district where an overt act was
    committed in furtherance of its objects . . . [and the] overt act . . . need not be itself
    a crime.” 
    Schlei, 122 F.3d at 975
    (internal citations and punctuation omitted). The
    foregoing evidence is uncontroverted. There is overwhelming evidence that overt
    acts in furtherance of the conspiracy occurred in Pensacola. In sum, there was
    overwhelming evidence that venue existed there. Thus, any error was harmless.
    B.     Deliberate ignorance
    Pastorek argues that the district court erred when it instructed the jury on
    deliberate ignorance. 5 He asserts that this court has stated that the instruction
    should be given only in rare cases where the facts point in the direction of
    5
    Caroni and DiLeo adopt this argument.
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    deliberate ignorance, but that in this case, the Government argued that the
    Defendants knew what they were doing and took steps to cover their tracks. The
    two battling theories of the case were that the Defendants knew the controlled
    substances were being issued outside their usual course of medical practice or that
    the substances were being prescribed pursuant to a legitimate medical purpose.
    Neither, he argues, supports the deliberate ignorance factual predicate of
    defendants being subjectively aware of a high probability that controlled
    substances were being issued outside the usual course of medical practice and that
    they deliberately contrived to avoid discovering or confirming this. He further
    argues that the error was not harmless: giving the instruction, without the proper
    factual predicate, runs the risk that the jury will convict based on a belief that the
    Defendants were negligent or reckless in failing to learn of the alleged illegal
    activity, rather than that they had actual knowledge of it.
    This court gives wide discretion to the style and wording of instructions on
    deliberate ignorance. Such an instruction is justified when the facts “support the
    inference that the defendant was aware of a high probability of the existence of the
    fact in question and purposely contrived to avoid learning all of the facts in order
    to have a defense in the event of a subsequent prosecution.” United States v.
    Rivera, 
    944 F.2d 1563
    , 1571 (11th Cir. 1991). We have stated that when the
    deliberate ignorance instruction is correctly given, and because by its own words
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    the instruction did not apply because there was insufficient evidence to prove
    deliberate ignorance, there was no reason to believe that the jury convicted the
    defendant on it and such an instruction is harmless per se. United States v. Stone,
    
    9 F.3d 934
    , 939, 941-42 (11th Cir. 1993). In Stone, we determined that the
    instruction was clear in setting as a precondition of finding the defendant guilty of
    deliberate ignorance that there was proof beyond a reasonable doubt that he
    deliberately kept himself ignorant. 
    Id. at 937-38.
    Rejecting the defendant’s
    argument that the jury had not followed the instruction, we reasoned that as long as
    one theory of conviction was supported by evidence, the error is harmless. 
    Id. at 939.
    Further, where one theory was supported, the jury will be presumed to have
    made the proper choice. 
    Id. Finally, we
    rejected the ideas that a jury instructed on
    deliberate ignorance in the absence of evidence would employ a reckless or
    negligence standard or that by finding this error harmless, the appellate court
    substituted itself for the jury. 
    Id. at 941.
    Stone thus stands for the principle that a jury, when presented with two
    alternate theories, will take the instructions to heart and apply them. Here, there
    was evidence that the Defendants ignored evidence that their patients were abusing
    the prescribed substances: they did not order routine and inexpensive drug screens
    to ensure that the patients were complying with the prescriptions, they refilled
    prescriptions early without questioning, they did not administer physical exams to
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    ensure an underlying pathology, and they wrote blanket prescriptions based upon
    previous doctors’ scripts. Additionally, as discussed below, there was sufficient
    evidence to support the alternative theory. Thus, it was not error to instruct on
    deliberate ignorance.
    C. Prejudicial Evidence
    Caroni argues that his motion for mistrial should have been granted after the
    jury was improperly exposed to evidence about two patients’ death (i.e., the deaths
    of J.P. and E.A.A.). 6 He also supported his mistrial motion with the fact that the
    jury was exposed to three letters from parents of two patients – complaining to the
    clinics or to the Louisiana State Board of Medical Examiners (“LSBME”) that the
    clinics’ prescriptions caused overdoses, and urging the clinics to stop prescribing
    to their son. There were four such letters, all admitted for the purpose of showing
    that Defendants had notice that their prescriptions were being misused and were
    creating dangerous health conditions. After it became apparent that the clinics had
    not received three of the four letters, the jury was instructed that Defendants had
    had no knowledge of those letters, which therefore could not serve as notice to
    them that their prescriptions were being misused.
    The prosecution stated, during opening argument, that Defendants were
    responsible for the deaths and had ignored letters from the patients’ parents asking
    6
    Both Pastorek and DiLeo adopt this argument.
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    them to cease giving the patients drugs. The jury heard from one patient’s (J.P.’s)
    girlfriend who was with him when he had a seizure and crashed his car into a tree,
    killing him. The Government put the state trooper who responded to the accident
    on the stand as well as the coroner who issued the death certificate but did not do
    the autopsy. The director of the lab testified and introduced into evidence the
    toxicology report, and opined that J.P.’s level of methadone was sufficient to cause
    death. After receiving that toxicology report, J.P.’s autopsy report was modified to
    reflect that the cause of death was an overdose. However, the director of the
    toxicology lab later testified that he had not conducted the tests himself or done the
    analyses underlying the report, causing the defense to move to strike his testimony.
    Similarly, the other victim’s (E.A.A.’s) daughter testified about her mother’s drug
    addiction and death. After a friend also testified, the prosecution admitted that it
    did not have the person who performed the toxicology report available to testify,
    and therefore the prosecution admitted that it could not prove the cause of death.
    At that point, the Justice Department advised the prosecution that it should
    concede the inadmissibility of the autopsy evidence. The court then instructed the
    jury that it would not be asked to consider whether the deaths resulted from the
    conspiracy charge, and that it must not consider that part of the indictment. The
    court instructed the jury to disregard all of the evidence introduced about the
    deaths. In particular, the jury was instructed as follows:
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    [Y]ou will not be asked in this case to consider whether
    death resulted to [J.P.] and/or [E.A.A.] from the
    conspiracy charged in the indictment. And you must not
    consider this part of the indictment in any way for any
    purpose during your deliberations. As a result, you are
    instructed that you must disregard all of the evidence
    introduced in the trial regarding the circumstances
    surrounding and the cause of the deaths of [J.P.] and
    [E.A.A.]. This would include all of the testimony of the
    following witnesses: the toxicologist, Robert Middleberg;
    the coroner, Tom Wilson; the Alabama Trooper, James
    Ray; and the medical examiner, Dr. Emily Ward.
    You must also disregard portions of the testimony
    of the following witnesses: Lisa Riddle, who was
    [E.A.A.’s] daughter; Joyce Bohannon, who we heard
    from yesterday afternoon, who was [E.A.A.’s] friend;
    and then, Hollie Thompson, who was [J.P.’s] fiancé.
    You must disregard the portions of their testimony that
    specifically referred to the circumstances surrounding
    and the cause of their deaths.
    Docket 656:25:3-27:13 (format changed). This contemporaneous instruction was
    repeated almost verbatim in the court’s final instructions to the jury.
    Caroni also identifies as prejudicial letters from a patient’s parent to the
    clinic that expert Dr. Parran read into evidence. The letters asked the clinic to stop
    prescribing to her son because he almost died of an overdose. The government
    argued that the letters were relevant to show that the defendants knew what their
    actions were causing. This parent wrote three letters, but only the first was
    received before the patient was discharged by the clinic. Although the government
    conceded that the defendants had not received the last two letters before the
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    patient’s final office visit, the court allowed the mother to testify why she had
    written the letters and to identify the letters. The court gave a limiting instruction
    with respect to the two letters which were not received before the patient’s final
    office visit. Expert Dr. Parran also discussed another patient whose mother had
    written a letter of complaint to LSBME, but the intended copy of that letter was
    never received by the defendants. The court struck that letter, but stated that the
    jury could consider the patient’s mother’s testimony about writing the letter and
    the fact that she had made a complaint.
    Caroni had moved for a mistrial after the government rested, which the court
    denied. Caroni argued that the evidence was so prejudicial that, even though
    curative instructions were given, they could not cure the damage done.
    We review a district court’s refusal to grant a mistrial for an abuse of
    discretion. United States v. Trujillo, 
    146 F.3d 838
    , 845 (11th Cir. 1998). “The
    decision of whether to grant a mistrial lies within the sound discretion of a trial
    judge as he or she is in the best position to evaluate the prejudicial effect of
    improper testimony.” United States v. Perez, 
    30 F.3d 1407
    , 1410 (11th Cir. 1994).
    “When a curative instruction has been given to address some improper and
    prejudicial evidence, we will reverse only if the evidence ‘is so highly prejudicial
    as to be incurable by the trial court’s admonition.’” 
    Id. (quoting United
    States v.
    Funt, 
    896 F.2d 1288
    , 1295 (11th Cir. 1990)).
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    In United States v. Ignasiak, 
    667 F.3d 1217
    (11th Cir. 2012), we held that
    the admission of autopsy reports and testimony about them by a physician who was
    not their author was a violation of the Confrontation Clause. We determined that
    the admission of the reports and the testimony was not harmless. Because it was a
    constitutional error, we reviewed under a more stringent standard: “whether it
    appears beyond a reasonable doubt that the error complained of did not contribute
    to the verdict obtained.” 
    Id. at 1235.
    We stated that we could not ignore the
    powerful impact the reports must have had, and we also noted that the jury was
    allowed to consider the testimony concerning seven deaths. 
    Id. Furthermore, knowledge
    of the deaths undermined the defendant’s good faith defense. 
    Id. at 1236.
    Unlike in Ignasiak, the prejudicial evidence about the deaths in this case was
    excluded, and the jury was instructed not to consider it. Additionally, the jury was
    instructed that the clinic did not receive the three challenged letters and the jury
    was instructed that it could consider those letters only for the limited purpose of
    revealing what the two patients’ families thought of the clinic but not as notice to
    the clinic or the defendants about the effect of the prescriptions.
    Because the evidence about the deaths was excluded, there was no
    Confrontation Clause violation and thus we need not employ the more stringent
    standard of review that the court used in Ignasiak. Because the court gave clear
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    instructions to the jury to disregard the evidence, we instead review for whether the
    evidence was so highly prejudicial as to be incurable. 
    Perez, 30 F.3d at 1410
    .
    Our careful review of the entire record persuades us that the jury’s exposure
    to the evidence relating to the two deaths and to the challenged letters was not so
    highly prejudicial as to be incurable. As noted, the jury was clearly instructed –
    both shortly after the exposure to the inadmissible evidence of the deaths and in the
    final instructions – to “disregard all of the evidence introduced . . . regarding the
    circumstances surrounding and the cause of the deaths.” Similarly, strong and
    proper curative instructions were given at both times with respect to the challenged
    letters. With respect to the latter, there was ample other evidence that the
    defendants were aware that the prescriptions were causing or contributing to
    addiction or overdoses. With respect to the exposure to the evidence of the deaths,
    the jury is presumed to have followed the clear instructions to disregard same. Our
    careful review of the totality of the evidence persuades us that the jury could and
    did do that.
    In its closing arguments, the government did not comment at all on the death
    evidence that was ruled inadmissible. Moreover, with respect to both deaths, the
    jury was also exposed to significant evidence that indicated either that the death
    was not in fact caused by the defendants’ prescriptions or that eroded the
    prejudicial effect of the inadmissible evidence. With respect to J.P., the jury was
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    exposed to evidence that he had obtained 120 methadone tablets from a Tennessee
    clinic a week before his fatal automobile accident, thus eroding any causal link
    between J.P.’s death and these defendants’ prescriptions. The jury could very
    readily, and most probably actually did, follow the judge’s instruction to disregard
    all of the evidence tending to link the drugs prescribed by these defendants as a
    cause of J.P.’s death. With respect to E.E.A., the jury was also exposed to
    evidence that she had cervical cancer, thus eroding the prejudicial impact of the
    jury’s exposure to the inadmissible evidence with respect to her death, and making
    it easier for the jury to follow the judge’s instruction. Moreover, there was ample
    other evidence that the strength and combination of the drugs being prescribed by
    these defendants, and their modus operandi, had the potential to cause serious
    harm, and ample other evidence that defendants’ prescriptions had actually caused
    overdoses. In light of the totality of the evidence in this case, we do not believe
    that the inadmissible evidence that the jury was clearly instructed to disregard was
    so highly prejudicial as to be incurable.
    With respect to the totality of the evidence in this case, unlike the Ignasiak
    case, the evidence of these defendants’ guilt was strong. Numerous patients and
    former employees testified that the drugs were prescribed notwithstanding the
    complete absence of, or only cursory, physical examinations. They also testified
    that patients were able to obtain prescriptions despite obvious indications of
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    addiction, abuse of the drugs, and doctor-shopping. There was evidence that the
    number of patients the doctors saw each day was very large; that patients were
    offered bonuses for referrals; and that patients’ dosages were increased upon
    request (i.e., not based upon demonstrable need) and in spite of drug screening
    indicating that the patients were not taking the drugs and, in some cases, were
    taking street drugs. There was significant evidence from employees, including Dr.
    Klug, that defendants Caroni and DiLeo actually said that what the patients did
    with the drugs after they left the office was none of their business or concern. And
    there was evidence that patients were selling some of the drugs prescribed, and at
    least some evidence that co-conspirator Caroni was aware of that. Dr. Klug also
    testified that, when he sought guidance because of his own inexperience with pain
    management, Dr. DiLeo advised him to just prescribe the same controlled
    substances that the patient had been receiving. The evidence showed that
    defendants charged fees depending upon the type and strength of the controlled
    substance, much more like drug dealers than like professionals who base their fees
    on the time expended and/or the complexity or value of the service. Significant
    testimony also came from Dr. Lonseth, who brought his family to New Orleans
    from California to accept a position with Global Pain at a salary of $500,000.
    After observing the operation for a less than a month, he walked away from the
    $500,000 salary (notwithstanding he had no other current offer) because he thought
    20
    Case: 13-10661      Date Filed: 09/01/2015   Page: 21 of 47
    the operation was a “pill mill.” Two former staff members also estimated that
    about three-fourths of the patients were there to support their addictions. Although
    there was some conflict in the expert testimony, the foregoing evidence provides
    strong support for the opinions of the two government experts – Dr. Parran and Dr.
    Hamill-Ruth – that the operation of Global Pain was inconsistent with the legal
    requirement that prescriptions for controlled substances must be issued for
    legitimate medical purposes in the usual course of a professional practice.
    In sum, we cannot conclude that the district court abused its discretion in
    denying defendant’s motion for a mistrial.
    D.    Sufficiency of evidence – conspiracy
    Caroni argues that the evidence was legally insufficient to support his
    conviction for conspiring with his co-defendants to run an illegitimate practice. 7
    Under 21 CFR § 1306.04(a), “a prescription for a controlled substance to be
    effective must be issued for a legitimate medical purpose by an individual
    practitioner acting in the usual course of his professional practice.” The indictment
    alleges that DiLeo, Pastorek, and Caroni conspired to unlawfully distribute
    Schedule II, III, and IV controlled substances through prescription practices done
    outside the usual course of medical practice and for other than legitimate medical
    7
    Both Pastorek and DiLeo adopt this argument.
    21
    Case: 13-10661        Date Filed: 09/01/2015        Page: 22 of 47
    purpose. Caroni asserts that the Government’s theory was that the clinics were pill
    mills but yet the clinics had employed nine doctors and only two were indicted.
    Caroni asserts that the Government alleged, and had to prove, an entirely corrupt
    practice. He also argues that the files reviewed by the experts were not statistically
    representative of the whole practice.
    We review questions about the sufficiency of the evidence de novo,
    “viewing the evidence in the light most favorable to the government, with all
    reasonable inferences and credibility choices made in the government’s favor.”
    United States v. Sosa, 
    777 F.3d 1279
    , 1289 (11th Cir. 2015) (internal quotations
    omitted and alterations adopted). Further, “we will affirm a conviction where ‘a
    reasonable jury could find the defendant’s guilt beyond a reasonable doubt.’” 
    Id. (quoting United
    States v. Utter, 
    97 F.3d 509
    , 512 (11th Cir. 1996)).
    Caroni cites no cases that require the Government to show that the entire
    practice was illegitimate. This would be an unreasonable burden and allow a
    completely illegal clinic to evade prosecution by having a few legitimate patients.
    Rather, the Government needed to prove that there was very substantial illegal
    activity occurring at the clinic, thus removing any reasonable doubt that unlawful
    prescriptions were being issued by mistake or through negligence. 8 Thus, the
    8
    The district court expressly instructed the jury that “negligence, mistake or carelessness is
    not a sufficient finding of knowledge.”
    22
    Case: 13-10661      Date Filed: 09/01/2015    Page: 23 of 47
    selection of the files for the experts to review did not need to precisely reflect the
    composition of the clinic’s patient population; rather, it had to demonstrate that the
    illegal behavior was substantial and it did just that.
    In United States v. Joseph, 
    709 F.3d 1082
    (11th Cir. 2013), we upheld a
    jury’s finding of an illegitimate practice. There, we pointed to the defendant’s
    prescription of large quantities of controlled substances, the large number of those
    prescriptions, failure to do physical examinations, prescriptions to patients
    knowing they were giving them to others, and no relationship between the drug
    prescribed and the treatment of the condition alleged.
    The evidence in this case was similar to that in Joseph. As set forth in the
    immediately preceding Part C. of this opinion, there was ample evidence to support
    the jury’s verdict. And while there was some evidence that the Defendants became
    more careful about doctor shopping and misuse of prescriptions in the last year of
    the clinic, a reasonable jury could have concluded this was a response to the
    shutting down of other pain management clinics by the DEA and an effort to evade
    detection.
    23
    Case: 13-10661        Date Filed: 09/01/2015   Page: 24 of 47
    E.     Sufficiency of evidence – money laundering
    Caroni argues that the Government produced insufficient evidence to prove
    promotion money laundering. 9 To prove promotion money laundering, the
    Government must show not only that the money was the result of illegal activity
    but also that it was spent on promoting the illegal activity. Caroni argues that the
    evidence only showed that cash was deposited into bank accounts, using simple
    graphs prepared by the agent.
    Caroni is correct that our precedent requires the Government to show that
    the deposited money was intended promote the conspiracy. In United States v.
    Calderon, we reversed a conviction because the Government only showed that the
    Appellant knew that the money was ill-gained but never put on any evidence that
    the Appellant intended to do more than conceal the money. 
    169 F.3d 718
    , 721
    (11th Cir. 1999). There was no evidence of how the money was to be spent once it
    was deposited or any evidence of how her actions furthered the underlying drug
    trafficking. 
    Id. Our United
    States v. Martinelli, 
    454 F.3d 1300
    (11th Cir. 2006), decision
    approved a district court’s instruction that the jury had to find that the defendant
    engaged in the financial transaction with “the intent to promote the carrying on of
    such specified unlawful activity” and that “[t]he term with the intent to promote the
    9
    DiLeo adopts this argument
    24
    Case: 13-10661    Date Filed: 09/01/2015    Page: 25 of 47
    carrying on of the specified unlawful activity means that the defendant must have
    conducted or attempted to conduct the financial transaction for the purpose of
    facilitating or making easier or helping to bring about the specified unlawful
    activity as has been defined.” 
    Id. at 1318.
    We stated that with such instructions,
    “the jury could not have found Martinelli guilty if it believed the financial
    transactions were undertaken for legitimate, non-fraudulent business expenses.”
    
    Id. Here, the
    jury was instructed with the same pattern jury instructions as in
    Martinelli. The agent who provided evidence about the monetary transactions
    testified that the funds at issue were used to pay overhead, rent, and malpractice
    insurance. Further, in Caroni’s deposition in a civil case, which was entered into
    evidence, he testified that they used the funds from Global Pensacola to pay “bills
    and whatnot.” Thus, the proceeds of the unlawful activity were deposited into
    numerous bank accounts and then spent to pay overhead, rent, malpractice
    insurance, bills, and whatnot – all expenses incurred to promote and continue the
    operation of the conspiracy to unlawfully dispense controlled substances.
    Accordingly, there was sufficient evidence that the funds were spent to promote
    the illegal practice.
    25
    Case: 13-10661      Date Filed: 09/01/2015   Page: 26 of 47
    F.     Indictment amendment
    Caroni argues that his Fifth Amendment rights were violated when the jury
    was charged in the disjunctive but the indictment read in the conjunctive. 10 Count
    One charged the Defendants with engaging in a conspiracy to unlawfully dispense
    controlled substances through prescription practices done outside the usual course
    of medical practice and for other than legitimate medical purposes. However, the
    Government’s proposed jury instructions stated that the jury only had to find one
    or the other. Caroni objected and asked for a ruling before opening arguments.
    The district court instructed the lawyers to avoid the standard in their openings and
    did not rule until 20 days into the trial, after the Government had rested. It
    overruled Caroni’s objection and instructed the jury in the disjunctive. Caroni
    argues that the charge impermissibly expanded the indictment by broadening the
    possible bases for conviction.
    Caroni points to our decision in United States v. Cancelliere, 
    69 F.3d 1116
    (11th Cir. 1995), where we held that the Government had to prove willfulness even
    though the statute did not include that language because the Government had put
    the word in the indictment. We so held because the entire defense was based on
    the defendant’s lack of willfulness and the Government did not seek to have
    willfulness removed until after the close of evidence. Here, Caroni contends that
    10
    Both Pastorek and DiLeo adopt this argument.
    26
    Case: 13-10661     Date Filed: 09/01/2015   Page: 27 of 47
    his entire defense was prepared based on the grand jury’s charges and changing the
    rules midstream was highly prejudicial.
    We have explained that a constructive amendment “takes place ‘when the
    essential elements of the offense contained in the indictment are altered to broaden
    the possible bases for conviction beyond what is contained in the indictment.’”
    United States v. Mozie, 
    752 F.3d 1271
    , 1283 (11th Cir. 2014)) (quoting United
    States v. Dortch, 
    696 F.3d 1104
    , 1111 (11th Cir. 2012)). We have stated
    repeatedly that when an indictment charges several means of violating a statute, a
    conviction may be obtained on proof of only one of the means. 
    Id. at 1283-84.
    In
    Mozie, we explained that in Cancelliere, there were some key differences. One
    was that willfulness was not an alternative means because it was not in the statute.
    
    Id. at 1284.
    Second, Cancelliere was different because the defendant based his
    entire defense on disproving the mental state that was removed. 
    Id. Finally, we
    stated that to the extent Cancelliere supported Mozie’s position, it was inconsistent
    with cases that came before it and they would trump Cancelliere. 
    Id. at 1285.
    Caroni’s argument fails for several reasons. This case is more like Mozie
    than Cancelliere. The disjunctive instruction was not error. Section 1306.04(a) of
    the code of Federal Regulations provides an exception to the prohibitions found in
    § 841 that ban the sale and provision of certain drugs. That regulation permits
    prescriptions for controlled substance if they are “issued for a legitimate medical
    27
    Case: 13-10661      Date Filed: 09/01/2015   Page: 28 of 47
    purpose by an individual practitioner acting in the usual course of his professional
    practice.” Thus, under the plain language of the regulation, in order to qualify for
    the exception, a defendant must have provided the prescription for both a
    legitimate medical purpose and while acting in the usually course of his profession.
    Without both, the defendant is subject to prosecution. Accord 
    Joseph, 709 F.3d at 1094
    (citing the regulation and holding “[i]f a prescription is issued without a
    legitimate medical purpose or outside the usual course of professional practice”, it
    is subject to criminal penalties). Hence, the Government needed only to prove one
    of the two prongs and the Defendants were on notice because the language of the
    section clearly mandated that requirement.
    G.     Caroni’s sentence
    1. General verdict precluded sentencing to an underlying object offense.
    Caroni asserts that in a multi-object conspiracy, a general verdict from the
    jury precludes the court from sentencing the defendant to an underlying object
    offense unless the court finds beyond a reasonable doubt that the defendant
    conspired to commit that particular object offense. He argues that his sentences
    should be limited by his three-year statutory maximum sentence for Count 1
    because the jury did not specifically find that he was guilty of conspiring to
    distribute Schedule II drugs. He also contends that the district court erred by
    failing to separately calculate his offense level for Count 2 under U.S.S.G. § 2S1.1
    28
    Case: 13-10661    Date Filed: 09/01/2015   Page: 29 of 47
    to determine what his highest guideline range was. He argues that the court’s use
    of § 2D1.1 to calculate his offense level for Count 2 in conjunction with the
    application of the statutory maximum sentence for Count 2 is unconstitutional.
    Pursuant to 18 U.S.C. § 1956, a person convicted for money laundering
    faces a maximum sentence of 20 years’ imprisonment. 18 U.S.C. §
    1956(a)(1)(B)(ii). The Sentencing Guidelines dictate that closely related counts
    shall be grouped together for sentencing purposes. U.S.S.G. § 3D1.2. In a case
    where the defendant is convicted of money laundering and convicted of the
    underlying offense from which the laundered funds were derived, the counts shall
    be grouped pursuant to § 3D1.2(c), and the highest offense level shall be applied.
    U.S.S.G. § 2S1.1, comment. (n.6); U.S.S.G. § 3D1.3(a). While typically it is
    necessary to determine the offense level for each of the counts, the formal
    determination of the offense level is unnecessary where it is clear that one count
    cannot have a higher offense level than another. U.S.S.G. § 3D1.3, comment.
    (n.2).
    Money laundering offenses are covered by § 2S1.1 of the Guidelines.
    U.S.S.G. § 2S1.1. Under § 2S1.1, the offense level of the underlying offense from
    which the laundered funds were derived is to be applied as long as it can be
    determined. U.S.S.G. § 2S1.1(a)(1). Offenses involving a conspiracy to distribute
    controlled substances are covered by § 2D1.1 of the Guidelines. U.S.S.G. § 2D1.1.
    29
    Case: 13-10661      Date Filed: 09/01/2015       Page: 30 of 47
    In determining the drug quantity for purposes of § 2D1.1, types and quantities of
    drugs not specified in the count of convictions may be considered. U.S.S.G. §
    2D1.1, comment. (n.12)(2011).11 Additionally, the court may approximate the
    drug quantity by considering various factors, including financial and business
    records. 
    Id. Caroni’s claim
    fails because the district court properly calculated his
    guideline range and neither of his sentences exceed their respective statutory
    maximum penalties. Because he was convicted of laundering the money that he
    derived from the drug offense, the district court properly grouped his counts.
    U.S.S.G. § 2S1.3, comment. (n.6). Because Caroni’s base offense level under §
    2S1.1 was set to the offense level of his underlying drug offense, and he was
    eligible for the role adjustment in connection with either provision, he had the
    same total offense level for both counts. See U.S.S.G. § 2S1.1(a)(1). As such, it
    was unnecessary to independently determine his offense level for both counts, and
    either one could be used as the highest offense level. See U.S.S.G. § 3D1.3(a);
    U.S.S.G. § 3D1.3, comment. (n.2). He was subsequently sentenced to concurrent
    sentences of 36 months for Count 1 and 240 months for Count 2, both within his
    respective statutory maximum penalties.
    11
    The district court employed the 2011 Guidelines because the trial took place that year.
    30
    Case: 13-10661      Date Filed: 09/01/2015      Page: 31 of 47
    Although Caroni argues that the court should have limited his sentence for
    Count 2 with his statutory maximum penalty for Count 1, he offers no authority to
    support this position, and the money laundering guidelines specifically require the
    use of the drug offense guidelines in cases like this without any directive to alter
    the respective statutory penalties. 12 Finally, he offers no authority to support his
    position that the court was not entitled to consider the Schedule II drugs involved
    in the drug offense under the Guidelines in determining his drug quantity. See
    U.S.S.G. § 2D1.1, comment. (n.12). Accordingly, Caroni’s challenge fails.
    2. Calculation of drug quantity
    Caroni challenges the court’s calculation of his drug quantity. He argues
    that the district court clearly erred in determining the drug quantity based upon his
    assertion that many of the drugs were prescribed legitimately and the court was
    required to exclude those drugs.
    This Court reviews the district court’s interpretation of the Sentencing
    Guidelines de novo and accepts its factual findings unless clearly erroneous.
    United States v. Jordi, 
    418 F.3d 1212
    , 1214 (11th Cir. 2005). In order to be clearly
    erroneous, the finding of the district court must leave this Court with a “definite
    and firm conviction that a mistake has been committed.” United States v.
    12
    We also reject Caroni’s arguments based on Apprendi v. New Jersey, 
    530 U.S. 466
    , 
    120 S. Ct. 2348
    (2000), and United States v. Allen, 
    302 F.3d 1260
    (11th Cir. 2002), because the
    pertinent statutory maximum is the one for money laundering.
    31
    Case: 13-10661     Date Filed: 09/01/2015    Page: 32 of 47
    Rothenberg, 
    610 F.3d 621
    , 624 (11th Cir. 2010). However, a factual finding
    cannot be clearly erroneous when the fact finder is choosing between two
    permissible views of the evidence. United States v. Saingerard, 
    621 F.3d 1341
    ,
    1343 (11th Cir. 2010). For sentencing purposes, the government bears the burden
    of establishing drug quantity by a preponderance of the evidence. United States v.
    Rodriguez, 
    398 F.3d 1291
    , 1296 (11th Cir. 2005). The court must ensure that the
    government carries this burden by presenting reliable and specific evidence.
    United States v. Lawrence, 
    47 F.3d 1559
    , 1566 (11th Cir. 1995).
    The district court did not rely on a limited subset of the patient files to
    conclude that all of the patients received illegitimate prescriptions, but instead
    analyzed all of the identified patient files to reach the conclusion that all of the
    prescriptions were not for a legitimate medical purpose and were outside of those
    usual course of medical practice. Thus, with respect to all of the controlled
    substances for which Caroni was held responsible, the district court made a finding
    of fact that they were not prescribed for a legitimate medical purpose. The
    evidence showed that patients were able to pick up their prescriptions, often
    without seeing a doctor, simply by making the required payments. Patients had to
    pay in all cash, and prescriptions were often given out to patients with addiction
    problems, to patients that appeared to be under the influence, and in situations
    where the prescribing doctor believed that medication was not necessary.
    32
    Case: 13-10661     Date Filed: 09/01/2015    Page: 33 of 47
    Furthermore, the government and the court excluded many of the patient files from
    the original 96 patient files that were seized and reviewed. The PSI initially
    considered 68 of the patient files, and only 67 were considered at sentencing
    following the government’s concession that one of the patients’ prescriptions
    should not be counted.
    Although Caroni argued that some of the patient files contained information
    suggesting that the patients legitimately needed the medication, he offered no
    reliable evidence to establish that the medications were for a legitimate medical
    purpose or within the usual course of medical practice. Caroni submitted the
    conclusions of his expert witness, Warfield, but the district court correctly noted
    that the weight of her opinion had to be tempered by the jury's guilty verdict.
    Accordingly, the district court did not clearly err in determining that a
    preponderance of the evidence supported the drug quantity specified in the PSI.
    3. Substantively unreasonable sentence
    Finally, Caroni argues that his sentences are substantively unreasonable. He
    contends that the court impermissibly concluded that the conspiracy involved
    Schedule II drugs. Additionally, he points to the sentencing disparity between his
    sentences and those of his codefendants to argue that the district court made a clear
    error in judgment. He also argues that the court improperly considered evidence of
    33
    Case: 13-10661      Date Filed: 09/01/2015     Page: 34 of 47
    the patient deaths and of Mark Artigues’s 13 conduct, evidence that he argues was
    not properly in the record. Finally, he asserts that the court prejudicially concluded
    that he was responsible for ruining the lives of the doctors involved in the cases
    when they were culpable for their own conduct.
    This Court reviews the reasonableness of a sentence under a deferential
    abuse of discretion standard. Gall v. United States, 
    552 U.S. 38
    , 41, 
    128 S. Ct. 586
    , 591 (2007). This Court may “set aside a sentence only if [it] determine[s],
    after giving a full measure of deference to the sentencing judge, that the sentence
    imposed truly is unreasonable.” United States v. Irey, 
    612 F.3d 1160
    , 1191 (11th
    Cir. 2010) (en banc).
    The district court must impose a sentence “sufficient, but not greater than
    necessary, to comply with the purposes” listed in 18 U.S.C. § 3553(a)(2), including
    the need to reflect the seriousness of the offense, promote respect for the law,
    provide just punishment for the offense, deter criminal conduct, and protect the
    public from the defendant’s future criminal conduct. 18 U.S.C. § 3553(a)(2). In
    imposing a particular sentence, the court must also consider the nature and
    circumstances of the offense, the history and characteristics of the defendant, the
    kinds of sentences available, the applicable guideline range, the pertinent policy
    13
    Artigues was the former employee whom Caroni sued when he alleged that Artigues stole
    the Pensacola clinic from him.
    34
    Case: 13-10661      Date Filed: 09/01/2015   Page: 35 of 47
    statements of the Sentencing Commission, the need to avoid unwarranted
    sentencing disparities, and the need to provide restitution to victims. 18 U.S.C.
    §3553(a)(1), (3) (7).
    In reviewing the reasonableness of a sentence, this Court first ensures that
    the sentence was procedurally reasonable, meaning the district court properly
    calculated the guideline range, treated the Guidelines as advisory and not
    mandatory, considered the § 3553(a) factors, did not select a sentence based on
    clearly erroneous facts, and adequately explained the chosen sentence. 
    Gall, 552 U.S. at 51
    , 128 S. Ct. at 597. The Guidelines dictate that where a sentence
    imposed on the count carrying the highest statutory maximum is less than the total
    punishment, then the sentence imposed on the other count shall run consecutively
    to the extent necessary to produce a combined sentence equal to the total
    punishment. U.S.S.G. § 5G1.2(d). Once the Court determines that a sentence is
    procedurally sound, it examines whether the sentence was substantively reasonable
    in light of the totality of the circumstances. 
    Id. “The party
    challenging the sentence bears the burden to show it is
    unreasonable in light of the record and the § 3553(a) factors.” United States v.
    Tome, 
    611 F.3d 1371
    , 1378 (11th Cir. 2010). Although this Court does not apply a
    presumption of reasonableness for sentences falling within the guidelines range,
    “ordinarily [this Court] would expect a sentence within the Guidelines range to be
    35
    Case: 13-10661      Date Filed: 09/01/2015    Page: 36 of 47
    reasonable.” United States v. Talley, 
    431 F.3d 784
    , 787-88 (11th Cir. 2005). This
    Court reverses only if “left with the definite and firm conviction that the district
    court committed a clear error of judgment in weighing the § 3553(a) factors by
    arriving at a sentence that lies outside the range of reasonable sentences dictated by
    the facts of the case.” 
    Irey, 612 F.3d at 1190
    . “The fact that the appellate court
    might reasonably have concluded that a different sentence was appropriate is
    insufficient to justify reversal of the district court.” 
    Gall, 552 U.S. at 51
    , 128 S. Ct.
    at 597.
    Congress has explicitly provided that there is no limitation on the
    information concerning “the background, character, and conduct” of the defendant
    that a court may consider in determining the appropriate sentences. 18 U.S.C. §
    3661. At sentencing, a court’s factual findings may be based on trial evidence,
    undisputed statements in the PSI, or evidence presented at the sentencing hearing.
    United States v. Wilson, 
    884 F.2d 1355
    , 1356 (11th Cir. 1989).
    First, the district court did not err in considering evidence regarding Artigues
    or the patient deaths. The Caroni deposition testimony recounted how two Global
    Pain employees were hired to work at Artigues’s clinic, and the clinic’s earnings
    went to Caroni, who would then pay Artigues. It was also permissible for the court
    to consider the evidence of the patient deaths because that evidence was introduced
    at sentencing. 
    Wilson, 884 F.2d at 1356
    . Regardless, any error with respect to the
    36
    Case: 13-10661     Date Filed: 09/01/2015    Page: 37 of 47
    consideration of the death evidence was harmless because the court stated that it
    did not affect Caroni’s sentences.
    As to his argument regarding the consideration of Schedule II drugs in
    calculating his drug quantity, such consideration is expressly contemplated by the
    Guidelines. See U.S.S.G. § 2D1.1, comment. (n.12). Likewise, the court’s partial
    attribution of the consequences the doctors faced to Caroni is consistent with the
    determination that he held a leadership role in the offense, and the court stated that
    it was not absolving the doctors of their own conduct. While Caroni is correct in
    pointing out that his sentences are significantly higher than those of DiLeo and
    Pastorek, their sentences are the result of “extraordinary” situations that warranted
    significant departures. DiLeo initially had a sentencing range of 188 to 235
    months, the same range Caroni would have had without the leadership role
    adjustment. He received a 12-level departure because of the medical condition and
    special needs of his child, which resulted in a guideline range of 51 to 63 months.
    From there, the court imposed concurrent sentences of 24 months for both counts,
    representing a 27-month variance from the low end of his guideline range.
    Pastorek started with a much lower initial sentencing range because he was only
    charged and convicted for Count 1, and his guideline range was limited by his
    statutory maximum penalty. He received a 6-level departure for the medical
    37
    Case: 13-10661    Date Filed: 09/01/2015    Page: 38 of 47
    condition and medical needs of his child, and he was sentenced to 12 months and 1
    day of imprisonment, which was within his guideline range.
    By contrast, Caroni’s otherwise applicable guideline range was 292 to 365
    months. Under § 5G1.2(d), the court should have imposed his statutory maximum
    sentences consecutively to approximate his recommended guideline range, which
    would have resulted in a sentence of 276 months. Thus, his total sentence of 240
    months represented a downward variance of 36 months, which is actually greater
    than the variance that DiLeo received. Accordingly, the disparities in the
    sentences are explained by the differences in circumstances between the three
    defendants.
    Finally, Caroni’s sentences are reasonable in light of the record as a whole.
    The district court thoroughly considered the § 3553(a) factors, the trial evidence,
    and the arguments of the parties. The court emphasized that it believed strong
    sentences were warranted based on the seriousness of the offenses and Caroni's
    role in perpetuating them. The nature and scope of Caroni's conduct resulted in the
    distribution of the equivalency of 16,517.99 kilograms of marijuana and resulted in
    the laundering of approximately $8,557,205 in funds. Further, his 240-month
    sentences represented a downward variance from his applicable guideline range, as
    discussed above. Given the seriousness and magnitude of the offenses, Caroni’s
    leadership role in the offenses, and the district court’s consideration of the §
    38
    Case: 13-10661    Date Filed: 09/01/2015   Page: 39 of 47
    3553(a) factors, Caroni’s sentences are substantively reasonable. Accordingly, this
    Court affirms Caroni’s sentences.
    AFFIRMED.
    39
    Case: 13-10661       Date Filed: 09/01/2015   Page: 40 of 47
    MARTIN, Circuit Judge, dissenting:
    It is well-settled that the government bears the burden of proving venue in
    every criminal case. United States v. Snipes, 
    611 F.3d 855
    , 865 (11th Cir. 2010).
    Here, Dennis Caroni, Gerard DiLeo, and Joseph Pastorek were indicted and tried in
    the Northern District of Florida even though they never traveled to that district.
    Consistent with our long-standing precedent, the government alleged that venue
    was proper because the defendants briefly extended their drug and money
    laundering conspiracies to the Northern District of Florida by hiring co-
    conspirators to open Global Pensacola, a pain management clinic in Pensacola,
    Florida. See United States v. Schlei, 
    122 F.3d 944
    , 975 (11th Cir. 1997) (a
    conspiracy may be prosecuted in any district in which an “overt act was committed
    in furtherance of its objects”).
    The precise issue that Messrs. Caroni, DiLeo, and Pastorek raise is not that
    this is a legally insufficient allegation, or even that the government failed to offer
    evidence in support of it. Instead, they argue that because venue is a question of
    fact, they were entitled to have the jury make a specific finding that either they or
    one of their co-conspirators committed an overt act in the Northern District of
    Florida. I agree with Messrs. Caroni, DiLeo, and Pastorek, as well as the majority,
    that the District Court erred by refusing to provide a jury instruction on venue and
    40
    Case: 13-10661       Date Filed: 09/01/2015       Page: 41 of 47
    prohibiting defense counsel from arguing that the government had failed to prove
    venue.
    I part ways with the majority with respect to its holding that the District
    Court’s error was harmless. I write separately to explain why the District Court’s
    failure to instruct on venue and restriction of defense counsel’s closing arguments
    constitute reversible error.
    I.
    A defendant in a criminal case has the right to be tried in the district in
    which the crime was committed. For conspiracy offenses that span more than one
    district, venue is proper in any district in which the conspiracy was formed or in
    which a co-conspirator committed an act in furtherance of the conspiracy. 
    Schlei, 122 F.3d at 975
    .
    Questions of venue are not merely “pedantic, justice-defeating
    technicalit[ies],” but issues of constitutional magnitude. Green v. United States,
    
    309 F.2d 852
    , 856 (5th Cir. 1962). 1 As the Supreme Court explained in United
    States v. Johnson, 
    323 U.S. 273
    , 
    65 S. Ct. 249
    (1944), venue “touch[es] closely the
    fair administration of criminal justice and public confidence in it” by protecting
    defendants from prosecution in unfavorable or remote locations. 
    Id. at 276,
    278,
    1
    In Bonner v. City of Prichard, 
    661 F.2d 1206
    (11th Cir. 1981) (en banc), this Court
    adopted as binding precedent all of the decisions of the former Fifth Circuit handed down prior
    to the close of business on September 30, 1981. 
    Id. at 1207.
    41
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    47 65 S. Ct. at 250
    , 252. Indeed, the importance of this right is evident from the fact
    that it is guaranteed by two separate constitutional provisions and a federal statute.
    See U.S. Const. art. III, § 2, cl. 3 (“The Trial of all Crimes . . . shall be held in the
    State where the said Crimes shall have been committed . . . .”); 
    id. amend. VI
    (requiring trial “by an impartial jury of the State and district wherein the crime
    shall have been committed”); Fed. R. Crim. P. 18 (“Unless a statute or these rules
    permit otherwise, the government must prosecute an offense in a district where the
    offense was committed.”).
    Because it is grounded in our constitution, we have characterized venue as
    an “essential element of the government’s proof at trial,” 
    Snipes, 611 F.3d at 865
    ,
    and continuously reaffirmed that the government bears the burden of proving
    venue in every criminal prosecution, see, e.g., United States v. Stickle, 
    454 F.3d 1265
    , 1272 (11th Cir. 2006); United States v. Breitweiser, 
    357 F.3d 1249
    , 1253
    (11th Cir. 2004); United States v. White, 
    611 F.2d 531
    , 534 (5th Cir. 1980). And
    we have also explained that it is especially important for courts to safeguard a
    defendant’s venue right in conspiracy prosecutions because a jury need not find
    that the government proved every act alleged in the indictment in order to convict.
    Thus, “[t]he dangers of abuse are manifold if the Government can obtain an
    indictment for conspiracy in a district other than the district where the offense was
    42
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    actually committed merely by alleging that one act, which need never be proved,
    was committed in that district.” 
    Green, 309 F.2d at 856
    .
    However, although venue is a question of fact—did the crime take place in
    the district of prosecution?—our precedent makes clear that a district court is not
    always required to present this question to the jury. Compare Bellard v. United
    States, 
    356 F.2d 437
    , 439 (5th Cir. 1966), with 
    Snipes, 611 F.3d at 866
    ; see also
    United States v. Perez, 
    280 F.3d 318
    , 330 (3d Cir. 2002) (stating that “venue does
    not automatically present a question for the jury”). This Court last addressed the
    specific question raised by the appellants—in what circumstances a district court
    errs by failing to instruct the jury on venue—in White, 
    611 F.2d 531
    . In that case,
    Charles White was convicted in the Middle District of Florida for a number of
    offenses arising from the theft and forgery of a Social Security check. 
    Id. at 533–
    34. Mr. White argued that the district court erred by failing to give a jury
    instruction on venue because the government had offered no direct evidence that
    his crimes had been committed in the Middle District. 
    Id. at 535–36.
    We held that the district court’s failure to provide a venue instruction did not
    constitute plain error 2 for the following reasons:
    First, Count Two of the indictment charged that White forged the
    check in the Middle District of Florida. The indictment appears to
    2
    Unlike the appellants in this case, Mr. White did not request a jury instruction on venue.
    
    White, 611 F.2d at 536
    .
    43
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    have been read to the jury only once, before the jury was sworn, but
    the trial judge sent a copy of the indictment into the jury room for
    consideration by the jury during its deliberations. Second, in
    instructing the jury on the essential elements of forgery, the trial court
    stated that the government must prove beyond a reasonable doubt “the
    act of forging the payee’s endorsement on the United States Treasury
    check as charged.” Third, White’s counsel argued the territorial
    jurisdiction and venue question in his closing argument. Finally, there
    was sufficient evidence for a jury to conclude that the forgery
    occurred in the Middle District of Florida.
    
    Id. at 537.
    White’s reasoning is instructive: no separate venue instruction was required
    because the jury’s guilty verdict necessarily included a finding of proper venue. In
    other words, because the indictment alleged offense conduct only in the Middle
    District of Florida, the jury could not have found the defendant guilty unless it
    specifically found that the defendant committed an act within that jurisdiction. See
    
    id. Several other
    circuits have articulated similar rules. See, e.g., United States v.
    Miller, 
    111 F.3d 747
    , 751 (10th Cir. 1997) (“We therefore adopt the rule that
    failure to instruct on venue, when requested, is reversible error unless it is beyond
    a reasonable doubt that the jury’s guilty verdict on the charged offense necessarily
    incorporates a finding of proper venue.”); United States v. Martinez, 
    901 F.2d 374
    ,
    376 (4th Cir. 1990) (“Venue is an issue in this case because the jury was able to
    convict the defendant of the offenses charged without an implicit finding that the
    acts used to establish venue had been proven.”); United States v. Moeckly, 769
    44
    Case: 13-10661        Date Filed: 09/01/2015        Page: 45 of 
    47 F.2d 453
    , 461 (8th Cir. 1985) (“The issue here is whether venue was proven where
    there was no finding by the jury that at least one overt act or the conspiratorial
    agreement occurred in Minnesota . . . . Some finding by the jury on this issue
    should have been required.”).
    Applying this standard, the District Court erred. The indictment in this case
    alleged a conspiracy in both the Northern District of Florida and the Eastern
    District of Louisiana, and the jury’s guilty verdict did not necessarily incorporate a
    finding that the defendants committed any act—criminal or otherwise—in the
    Northern District of Florida. Thus, the District Court should have provided a jury
    instruction on venue and permitted defense counsel to argue that the government
    had failed to prove venue. The majority does not dispute this conclusion.
    The majority and I part ways, however, in our application of the harmless
    error standard. Under Chapman v. California, 
    386 U.S. 18
    , 
    87 S. Ct. 824
    (1967),
    Messrs. Caroni, DiLeo, and Pastorek are entitled to reversal unless the government
    “prove[s] beyond a reasonable doubt that the error complained of did not
    contribute to the verdict obtained.” 3 
    Id. at 24,
    87 S. Ct. at 828. Under these
    3
    To the extent that the majority applies some other harmless error standard, it has no basis in our
    precedent. And although several of our sister circuits have held that a failure to instruct the jury
    on venue is harmless error if evidence of venue is “substantial and uncontroverted,”
    uncontroverted in this context takes its literal meaning: not contested at trial. See 
    Martinez, 901 F.2d at 377
    (holding that evidence of venue was “substantial and uncontroverted” where it had
    not been contested at trial); see also United States v. Neder, 
    197 F.3d 1122
    , 1129 n.6 (11th Cir.
    1999) (stating that the fact that an omitted element “was not contested supports the conclusion
    45
    Case: 13-10661       Date Filed: 09/01/2015       Page: 46 of 47
    circumstances, where the jury has made no finding on a required element of an
    offense, our inquiry focuses on “whether the record contains evidence that could
    rationally lead to a contrary finding with respect to the omitted element.” Neder v.
    United States, 
    527 U.S. 1
    , 19, 
    119 S. Ct. 1827
    , 1839 (1999). Said differently, the
    government bears the burden of proving, beyond a reasonable doubt, that a rational
    jury could not have concluded that venue was improper. I believe the government
    has failed to carry this burden.
    The majority makes much of the “substantial and uncontroverted” evidence
    regarding Global Pensacola. However, while it was not disputed that Mr. Caroni
    founded Global Pensacola, the relevant question here is whether its establishment
    was an overt act in furtherance of the conspiracy between Messrs. Caroni, DiLeo,
    and Pastorek such that it could establish venue in the Northern District of Florida.
    The evidence on this question was more limited. Global Pensacola operated for
    only two weeks during what was otherwise a four-year conspiracy, and Mr. Caroni
    was the only one of the three defendants who had a role in founding the clinic.
    Indeed, the government presented no evidence whatsoever linking Mr. Pastorek to
    that the jury’s verdict would have been the same absent the error.” (emphasis added)). The
    defendants here contested whether their conspiracy extended to the Northern District of Florida.
    46
    Case: 13-10661       Date Filed: 09/01/2015       Page: 47 of 47
    Global Pensacola. 4 Finally, as a result of the short amount of time that Global
    Pensacola operated, the government’s evidence about this clinic’s operations was
    necessarily quite limited. For instance, although a critical question in this case was
    whether patients received prescriptions that were made “outside the usual course of
    medical practice and for other than legitimate medical purposes,” the jury only
    heard from one Global Pensacola patient who had visited the clinic a single time
    and had not been treated by any of the defendants.
    For the reasons described in the majority opinion, it is certainly conceivable
    that the jury—if it had been presented with the question—would have found that
    venue was proper in the Northern District of Florida. But that is not our inquiry.
    Because this question was taken away from the jury in violation of the defendants’
    constitutional rights, our task on harmless error review is to determine whether
    there exists “evidence that could rationally lead to a contrary finding.” 
    Neder, 527 U.S. at 19
    , 119 S. Ct. at 1839. Under these facts, my answer is yes. I respectfully
    dissent.
    4
    I recognize that a co-conspirator may be held responsible for aspects of a conspiracy in which
    he had no direct involvement. However, the government’s inability to connect Mr. Pastorek to
    Global Pensacola is undoubtedly relevant to the question we face here—whether the
    establishment of Global Pensacola was an overt act in furtherance of a conspiracy involving Mr.
    Pastorek. See United States v. Chandler, 
    388 F.3d 796
    , 811–12 (11th Cir. 2004). As this Court
    explained in Green, “[t]here is grave danger of injustice where, as in the present case, one
    defendant was not even alleged to have participated in the one act which occurred in the district
    where the indictment against him . . . was 
    returned.” 309 F.2d at 856
    .
    47