United States v. Richard Evans ( 2018 )


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  •      Case: 17-20158    Document: 00514544493       Page: 1   Date Filed: 07/06/2018
    REVISED JULY 6, 2018
    IN THE UNITED STATES COURT OF APPEALS
    FOR THE FIFTH CIRCUIT
    United States Court of Appeals
    Fifth Circuit
    FILED
    No. 17-20158                         June 12, 2018
    Lyle W. Cayce
    cons. w/ 17-20159                                                            Clerk
    UNITED STATES OF AMERICA,
    Plaintiff - Appellee
    v.
    RICHARD ARTHUR EVANS,
    Defendant - Appellant
    Appeals from the United States District Court
    for the Southern District of Texas
    Before KING, HAYNES, and HIGGINSON, Circuit Judges.
    KING, Circuit Judge:
    After practicing medicine for over thirty years, Doctor Richard Evans
    decided to branch into pain management. Seven years, eleven thousand
    oxycodone prescriptions, and a couple of million dollars later, Evans faced
    federal criminal charges. According to the Government, Evans’s pain-
    management clinic was really a “pill mill”—an operation that prescribes drugs
    with no legitimate medical purpose. After a lengthy jury trial, Evans was
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    No. 17-20158
    convicted of distributing controlled substances, money laundering, mail fraud,
    and conspiracy.
    Evans now appeals. He claims the evidence at trial was insufficient for
    the jury to convict on some counts, legal flaws in the indictment tainted others,
    the district court bungled two evidentiary rulings, and his Confrontation
    Clause rights were violated. All Evans’s claims lack merit. With respect to
    Evans’s Confrontation Clause challenge, we assume without deciding that his
    rights were violated but nevertheless conclude that any error was harmless.
    Thus, we AFFIRM all Evans’s convictions and his sentence.
    I.
    A.
    In 2010, Doctor Richard Evans started seeing pain-management
    patients at his office located in Houston. Many of these patients transferred in
    from two other Houston pain-management clinics where Evans had practiced
    since 2008. Before that, Evans had primarily worked with car accident,
    workers’ compensation, and cancer patients.
    Around the time Evans’s pain-management patients transferred in, two
    women who worked at a dental office in Evans’s building, Kristi Smith and
    Donna Epley, started noticing changes. Cars with Louisiana license plates and
    loaded with up to six people would show up at Evans’s office. These cars would
    fill the lot, outnumbering the cars with Texas plates. Epley, who would usually
    arrive early in the morning and unlock the building, would see people waiting
    outside when she arrived. Evans’s office would be packed all day long, and
    people would loiter around the building. The pair noticed that the patient load
    would be heavy Monday through Thursday. The flow would ease up on Fridays,
    which—according to a sign in Evans’s waiting room—was the day that no
    prescriptions would be given out.
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    Smith and Epley noticed things about the newcomers. Some were
    unkempt or unhygienic. Others would use the wrong restroom or try to take
    baths in the sinks. One time, Smith watched as a woman washed and dried
    her hands over and over and over. Epley thought, based on her past work with
    addicts, that many of the newcomers seemed impaired, on something, or
    addicted. Once, a patient left Evans’s office, shaking a prescription with glee
    because he “got it.”
    The duo brought their concerns about Evans’s new clientele to the
    building’s management and Evans’s receptionist. Evans responded with a set
    of building rules. The rules regulated parking (“Patients who are in the
    parking lot prior to 8:15am may not be seen”), prohibited loitering (“Do NOT
    ‘hang out’ in any of our parking lots” or “in the hallways”), imposed a dress code
    (“Though it should go without saying, personal grooming/hygiene/clothing are
    important”),   and     limited   conversation   topics   in   the   waiting    areas
    (“[D]iscussions about medication/treatment may result in discharge”).
    After reading a newspaper article about pill mills popping up in Houston
    when Louisiana tightened its regulations on pain-management clinics, Smith
    and Epley grew suspicious. The pair started snooping through Evans’s trash.
    In it, they would find torn and re-taped prescriptions and handwritten letters
    requesting prescriptions (dosage and pill count often included). They also found
    a flyer, which explained the procedure patients could follow to get prescriptions
    via mail and for multiple months. According to the flyer, patients could either
    mail in a $240 money order for a month of prescriptions or bring in the money
    for additional months of prescriptions when they came in for their
    appointments (saving them $40). Patients were directed to “talk to David at
    Briargrove Pharmacy about mailing” their medications to them.
    Smith and Epley relayed their suspicions to law enforcement and the
    Texas Medical Board. In September 2012, federal agents raided Evans’s office
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    (which, Smith and Epley reported, stopped the flow of patients from
    Louisiana). Patient files, computers, and prescription pads were seized from
    Evans’s office. After this, Evans still saw patients, but just the “normal traffic
    load.”
    B.
    In 2015, a federal grand jury charged Richard Evans and David Devido,
    the owner of Briargrove Pharmacy (that filled many of Evans’s prescriptions),
    with several crimes: conspiracy under 18 U.S.C. § 371, six counts of
    distributing controlled substances without a legitimate medical purpose and
    outside the usual course of professional practice under 21 U.S.C. § 841, five
    counts of money laundering under 18 U.S.C. § 1957, and eight counts of mail
    fraud under 18 U.S.C. § 1341. Devido was also charged with four counts of
    health-care fraud for false claims under 18 U.S.C. § 1347.
    The six distribution counts pertained to six prescriptions for oxycodone
    Evans wrote for five of his patients from Louisiana. The five patients were
    Marvin Wampole (whose count was voluntarily dismissed by the Government
    at trial), Kimberly Richardson (whose prescriptions the Government charged
    in two separate counts), Stacy Cash, Audie Decoteau, and Shane Roper. The
    five money-laundering counts were based on five withdrawals Evans made
    from his account with Amegy Bank. The eight mail-fraud counts charged
    Evans with making false representations by writing prescriptions without
    adequate medical examinations, without proper recordkeeping, and without
    providing the proper standard of care. The mail was used in Evans’s scheme,
    per the indictment, when Evans received money orders through the mail from
    four patients and caused drugs to be sent via mail to the same four. The
    conspiracy count charged Evans and Devido with conspiring to do two crimes:
    distributing controlled substances and mail fraud.
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    C.
    The day Richard Evans and David Devido’s trial was to start, Devido
    struck a deal with the Government and pleaded guilty to obtaining possession
    of a controlled substance through misrepresentation in violation of 21 U.S.C.
    § 843(a)(3). No deal was struck with Evans, and his case went forward to trial.
    The Government began its case against Evans by calling Smith and
    Epley, who reported their observations and suspicion that Evans ran a pill mill
    (a conclusion Evans unsuccessfully objected to on the ground that it was
    outside their personal knowledge). Next, the Government called Brenda
    Clayton—one of Evans’s longtime medical assistants—to relay how Evans’s
    practice worked. Clayton, who has no advanced degree and only on-the-job
    training as a medical assistant, said that Evans’s other assistant, Rhoda
    Mann, would handle the new patients. Follow-up visits were Clayton’s
    business.
    Clayton discussed her role during these follow-up visits. She would ask
    the returning patient if he had any complaints and if the current dosage was
    adequate. If it was adequate, Clayton would fill out a prescription based on the
    patient’s chart. After the prescription was written up, Evans would enter the
    examination room, see the patient, and sign the already filled-out prescription.
    If, on the other hand, a patient asked for an increase in his dosage, Clayton
    would note it, tell Evans, and then Evans would decide what to do.
    Clayton also explained how a patient could get medication without an
    office visit. When a patient first started seeing Evans, if the patient wanted to
    stay on medication, he would have to come in every 30 days to get a 30-day
    prescription. But eventually, the patient would be told she could start coming
    in every 90 days.
    Two systems were devised to make sure the patient got 90 days of pills
    from only one visit. Some patients would get three 30-day prescriptions per
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    visit. One prescription could be filled immediately and the other two would
    have earliest-fill-by dates projected one and two months in advance. Other
    patients would get just one 30-day prescription from the visit. When their
    month-long supply of pills ran low, the patients would mail in $240 money
    orders along with notes requesting a refill.
    Clayton and Mann handled these letters. They would check the incoming
    mail to see if a money order was attached and then match the letter and money
    order to the patient’s files. They would then fill out the prescription based on
    the patient’s past dosage. These prescriptions were either signed later by
    Evans or had already been signed.
    These pre-signed prescriptions, according to Clayton, came about in two
    ways. Evans would keep some pre-signed prescriptions in a safe that the
    assistants could access. Alternatively, when the assistants were busy, they
    would leave Evans a prescription for him to sign but not fill in along with the
    file of the patient who sent in the money order. Evans, Clayton said, “didn’t
    change medications at mail ins.” Clayton also confirmed that the money order
    would be for a prescription, not an office visit. Once a prescription was ready
    to go, someone from the office would either mail it directly to the patient or
    take it to Briargrove Pharmacy to get it filled. From there, Briargrove would
    mail the pills to the patient.
    To explain what happened at Briargrove, the Government called Devido,
    who was the former owner and chief pharmacist of Briargrove. In late 2009,
    Devido noticed an increase in the number of prescriptions for opioids and other
    controlled substances coming from Evans. As Devido was unfamiliar with
    Evans, Devido called Evans to inquire into Evans’s practice. Evans told Devido
    that he was practicing pain medicine full time and discussed his procedure for
    admitting patients. Based on this conversation, Devido was satisfied that
    everything was above board.
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    But over time, Devido started to notice that Evans was frequently
    prescribing a suspicious mix—the combination of an opioid, a tranquilizer, and
    a muscle relaxer. This assortment, according to Devido, was a well-known and
    highly abused drug cocktail. One of Devido’s employees, Chris Helmke, noticed
    as well. Helmke wrote Devido a letter expressing concern about the number of
    prescriptions coming from Evans’s office. Helmke’s letter, which called Evans
    a “pill-mill” doctor whose patients’ “unsavory” appearance was attracting
    attention, was admitted over Evans’s hearsay and relevance objections. Devido
    admitted that he basically “turned a blind eye” to the volume of prescriptions
    because they brought in so much money.
    A DEA database confirmed what Devido said about Briargrove’s volume.
    Briargrove was the number one pharmacy in Texas for purchasing oxycodone
    and in the top fifteen for the nation in 2011. Evans’s prescriptions made up
    over 50 percent of Briargrove’s total. Briargrove’s output was not as high for
    2012, but it was on pace until Evans’s office was raided in September 2012. In
    total, from 2010 through 2012, Evans wrote over 11,000 prescriptions for
    oxycodone, coming out at over 1.6 million pills. Over that same period, Evans
    brought in over $2.4 million in cash, money orders, and checks from patients
    receiving those oxycodone prescriptions.
    In addition to volume and revenue, Devido talked about his role in
    Evans’s mail-order scheme. In January 2011, Rhoda Mann, one of Evans’s
    assistants, called Devido. Mann said she was calling on behalf of Evans and
    told Devido to expect a lot more patients from Louisiana. She also asked if
    Devido could start shipping the drugs to Louisiana so that Evans could
    establish a one-visit-every-three-months system. According to Devido, Mann
    told him that during a visit, Evans would fill out three prescriptions, give one
    to the patient and hold on to the other two. At the end of each month, Evans
    would call the patient to see if the patient needed the next month’s
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    prescription. If the patient did, someone from Evans’s office would bring the
    prescription to Briargrove where it would get filled and sent to the patient in
    Louisiana. Devido agreed to the plan and started shipping the drugs to
    Louisiana.
    Another key witness for the Government was Doctor Graves Owen, who
    reported on what and how much Evans was prescribing. For this part, it helps
    to know a few things about drugs and federal drug laws. Under federal law,
    controlled substances are classified into five Schedules, I through V.
    See 21 U.S.C. § 812(a). As the schedule number decreases, the potential for
    abuse and the addictive properties increase. See 
    id. § 812(b).
    Schedule I
    drugs—cocaine, heroin, methamphetamine, and the like—are deemed to have
    no medical use and thus cannot be legally prescribed under federal law. See 
    id. § 812(b)(1);
    21 C.F.R. § 1308.11. Schedule II drugs, while legal, are addictive
    and have a high potential for abuse. See 21 U.S.C. § 812(b)(2). Such drugs may
    generally only be obtained via a written prescription by a doctor. See 
    id. § 829(a).
    Oxycodone, a synthetic opioid sold under the name Roxicodone, is in
    Schedule II. See 21 C.F.R. § 1308.12(b)(1)(xiii). Hydrocodone is a semisynthetic
    opioid, which usually gets combined with a pain reliever like acetaminophen
    and sold under names like Vicodin, Lorcet, Lortab, and Norco. While
    hydrocodone is currently in Schedule II, see 21 C.F.R. § 1308.12(b)(1)(vi), at the
    time Evans was prescribing, it was in Schedule III. Although oxycodone and
    hydrocodone are different at the molecular level, their effects on the human
    body are very similar.
    According to Owen, Evans was prescribing high doses of oxycodone and
    hydrocodone, which, when combined with the other drugs he consistently
    prescribed, formed a popular drug cocktail. The cocktail included an opioid, a
    tranquilizer—usually Valium or Xanax—and a muscle relaxant—like Soma or
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    Mobic. Owen said that a doctor should know that this combination packed a
    punch and formed an abused drug cocktail.
    Owen explained the medical community’s standard for prescribing
    opioids and the deficiencies in Evans’s practice. Owen said that by at least
    2011, opioids were seen by the medical community as a high-risk treatment of
    last    resort.   Accordingly,   more   conservative   options—like    exercises,
    psychotherapy, and pain-relieving shots—should be exhausted before turning
    to opioids. And just because a patient comes in on opioids does not mean he
    should automatically get more. The doctor would need to examine past medical
    records to confirm that: conservative options were actually exhausted; the
    opioid was being taken; the patient was not acting aberrantly (doing things
    like using other drugs, reporting drugs lost or stolen, asking for early refills,
    or getting drugs from other doctors); and the drugs were improving the
    patient’s pain, function, and life.
    With this summary of the medical standard, Owen turned to the
    deficiencies he found when he studied 17 or 18 of Evans’s patient files. The
    files had “very superficial” medical history and inadequate medical records.
    While they contained MRIs and pharmacy pages with the patients’ most recent
    rounds of prescriptions, they did not hold records from past doctors who
    prescribed the drugs.
    Evans’s files also rarely documented any benefits from the drugs, a
    sign—according to Owen—that Evans was prescribing without heed. In fact,
    many patients reported increased or similar pain after being on medication for
    a sustained period, indicating that the drugs were not helping and other
    treatment was called for. Owen also saw that patients were exaggerating their
    symptoms—say, by regularly reporting that their pain was 10 (or even “10+”)
    out of 10. Such self-reporting is suspect, per Owen, and likely reflects the
    patient’s emotional or psychological suffering rather than physical pain. For
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    such patients, Evans failed to dig deeper to explain what was being reported
    or to refer the patient to someone who could.
    Owen further reported that the files contained few documented physical
    examinations and the examinations that were performed were inadequate.
    This was troubling, Owen said, because physical examinations are needed to
    confirm a patient’s symptoms and to track the physical effects of the drugs and
    other therapies. Owen acknowledged that some of the files had range-of-motion
    tests. But for those that did, it was unclear who performed the tests, and the
    results were often too precise to be credible. And, Owen pointed out, training
    in physical therapy—a qualification no one in Evans’s office possessed—would
    be required to perform an accurate range-of-motion test.
    Owen also found Evans’s risk-assessment tools to be subpar. Two such
    tests were used—the Screener and Opioid Assessment for Patients with Pain
    (SOAPP) and the Current Opioid Misuse Measure (COMM). But the results
    from these tests were not used for anything. Nor were any red flags—like a
    report of past drug problems—followed up on. And, Owen added, other risk
    factors not revealed by SOAPPs or COMMs should be considered, like the
    patient’s age, environmental stressors, and family or personal history of
    disorders or addictions. Out of the files Owen reviewed, only one had a drug-
    test result (which was positive for marijuana) and the test needed
    confirmation.
    Concluding, Owen did not see any evidence that the practice of medicine
    was going on. “It looked more like these were customers.” He found that Evans
    “failed to perform the basic responsibilities of a physician practicing medicine.”
    D.
    The defense case was that Evans ran a legitimate pain-management
    clinic. Through cross-examination of Government witnesses and calling former
    employees, Evans drew out the parts of his practice that did not involve
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    prescribing drugs, the precautions his office took, and that many of his patients
    had suffered debilitating injuries and experienced real pain.
    Evans established that his practice involved more than pain-
    management patients. He still saw some car accident, workers’ compensation,
    and cancer patients, as well as some patients requiring minor surgeries and
    seeking help with their weight. He was also certified to administer Suboxone,
    a medication designed to treat opioid addiction, and saw some patients
    suffering from addiction.
    To explain why his pain-management patients were driving the several
    hours from Louisiana to Houston, Evans established that the cost of
    appointments in Houston was lower. In 2008, Louisiana tightened its laws on
    pain medications, making it difficult for pain patients to see doctors and
    increasing the cost of doctors’ visits. Texas, on the other hand, did not impose
    such hurdles, and Evans could charge low-income and uninsured patients
    substantially less.
    Evans also drew out evidence about his clinic’s practices and
    precautions. When a new pain-management patient came in, the patient would
    have to fill out paperwork, submit a recent MRI, and present a pharmacy
    printout of current prescriptions. To verify that the MRI was correct, a member
    of Evans’s staff would call the MRI facility to make sure it was legitimate. If
    an MRI was confirmed as a fake, the patient’s appointment would be cancelled.
    If an MRI was too old, Evans would order a new one.
    Among the forms new patients had to sign were a patient contract and a
    pain-management agreement. Both agreements warned of the dangers of drug
    abuse and set forth general rules which, if violated, would result in the end of
    treatment. Under the agreements, patients were prohibited from “doctor
    shopping” (that is, visiting multiple doctors to obtain multiple prescriptions),
    “pharmacy shopping” (same idea as doctor shopping), selling their drugs, or
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    using drugs at greater than the prescribed rate. Patients also promised to
    honestly communicate, submit to drug tests, and bring excess drugs on visits.
    Evans also used a prescription-drug-monitoring database to confirm that
    patients were not doctor shopping. Several patients’ files reflected that they
    were discharged for violating these agreements. On top of these agreements,
    Evans had his patients perform two types of risk-assessment tests—the
    SOAPP and the COMM.
    Evans also established that his pain-management practice involved
    more than just churning out prescriptions. New pain-management patients
    were given brochures on the benefits of stretching and another on nonsurgical
    treatment for soft-tissue injuries. On visits, before a patient would see Evans,
    they would be weighed, have their blood pressure taken, and be shown
    exercises to help with their pain. Patients might then receive a massage,
    ultrasound, electric stimulation, or peg board (a device used to loosen tight
    muscles) treatment to help with the pain. Patients were also encouraged to do
    stretching at home and were given a journal to track their stretching. Patients
    would be asked to rate their pain, and the staff would keep track of it.
    After all these preparations, Evans would see the patient in an
    examination room. Evans called Rhoda Mann, his other assistant, to testify
    about what happened in the room. According to Mann, Evans would perform a
    physical examination, checking painful areas. Evans would then, according to
    Mann, decide whether to prescribe the patient a controlled substance. Mann
    admitted that most of the time, she would fill out the prescription and then
    have Evans sign it. On occasion, the assistant would retrieve a pre-signed
    prescription from Evans’s safe. According to Mann, Evans would pre-sign
    prescriptions so that when he was out of town his patients would not go into
    withdrawal.
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    Following up on that last point, Mann admitted during cross-
    examination that she thought the majority of Evans’s patients receiving
    opioids were chemically dependent. Mann also confirmed that after a patient’s
    initial visit, she could get a prescription or drugs mailed to them via money
    order. Patients would “order[]” a prescription, and a prescription would be
    written up and delivered to Briargrove or sent directly to the patient.
    The jury was unconvinced by Evans’s defense and found him guilty on
    all counts. The district court imposed a below-Guidelines sentence of 60
    months’ incarceration and three years’ supervised release. It also imposed a
    fine of $250,000, and ordered forfeiture of $268,336. Evans now appeals.
    E.
    On appeal, Evans claims that his convictions for distributing controlled
    substances, money laundering, and mail fraud should be reversed for lack of
    sufficient evidence. He also claims that the indictment was legally inadequate,
    necessitating reversal of his mail-fraud and conspiracy convictions. Next,
    Evans argues the district court erred in two evidentiary rulings—one allowing
    Smith and Epley to state that they thought Evans ran a “pill mill” and another
    admitting Helmke’s letter stating the same thing. Finally, he argues that his
    Confrontation Clause rights were violated when the district court limited the
    scope of his cross-examination of Clayton.
    We consider and reject each claim in turn.
    II.
    Evans’s three sufficiency-of-the-evidence challenges are evaluated “with
    substantial deference to the jury verdict.” United States v. Delgado, 
    672 F.3d 320
    , 330 (5th Cir. 2012) (en banc). We affirm if a reasonable juror could
    conclude that the elements of the crime were established beyond a reasonable
    doubt. See United States v. McDowell, 
    498 F.3d 308
    , 312 (5th Cir. 2007). We
    are obliged to view “the evidence in the light most favorable to the verdict” and
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    draw “all reasonable inferences from the evidence to support the verdict.”
    
    Id. (quoting United
    States v. Ragsdale, 
    426 F.3d 765
    , 770-71 (5th Cir. 2005)).
    “The evidence need not exclude every reasonable hypothesis of innocence or be
    wholly inconsistent with every conclusion except that of guilty, and the jury is
    free to choose among reasonable constructions of the evidence.” United States
    v. Lugo-Lopez, 
    833 F.3d 453
    , 457 (5th Cir. 2016) (per curiam) (quoting
    United States v. Salazar, 
    66 F.3d 723
    , 728 (5th Cir. 1995), abrogated in part by
    United States v. Sorrells, 
    145 F.3d 744
    (5th Cir. 1998)).
    As Evans’s sufficiency challenges were not properly preserved by an
    appropriately timed motion for acquittal, we review for plain error.
    See United States v. Jimenez, 
    509 F.3d 682
    , 690 (5th Cir. 2007). To
    demonstrate plain error, Evans must show a clear or obvious legal error that
    affects his substantial rights and “seriously affect[s] the fairness, integrity, or
    public reputation of judicial proceedings.” See Puckett v. United States, 
    556 U.S. 129
    , 135 (2009) (alteration in original). For a sufficiency challenge, an
    error is “clear or obvious” only when the record is “devoid of evidence pointing
    to guilt” or “the evidence of a key element of the offense [i]s so tenuous that a
    conviction would be shocking.” See United States v. Suarez, 
    879 F.3d 626
    , 630
    (5th Cir. 2018) (alteration in original) (quoting 
    McDowell, 498 F.3d at 312
    ).
    With this, we consider Evans’s three sufficiency challenges in turn. All
    three fail.
    A.
    Evans challenges the sufficiency of the evidence supporting three of his
    five convictions for distributing a controlled substance under 21 U.S.C. § 841.
    To convict on these counts, the Government was required to prove (1) that
    Evans “distributed or dispensed a controlled substance, (2) that he acted
    knowingly and intentionally, and (3) that he did so other than for a legitimate
    medical purpose and in the usual course of his professional practice.” See
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    United States v. Brown, 
    553 F.3d 768
    , 780-81 (5th Cir. 2008) (quoting United
    States v. Norris, 
    780 F.2d 1207
    , 1209 (5th Cir. 1986)). Evans does not quarrel
    with the evidence on elements one and two, so all the action turns on the last
    element—whether the three charged prescriptions had no legitimate medical
    purpose or were written outside the course of Evans’s professional practice.
    The three convictions under scrutiny relate to three oxycodone
    prescriptions Evans wrote for three different patients—Stacy Cash, Audie
    Decoteau, and Shane Roper. Evans’s attack is two-pronged. First, he asserts
    that the evidence supporting these convictions was not sufficiently
    particularized. Relying primarily on a Fourth Circuit case, United States v.
    Tran Trong Cuong, 
    18 F.3d 1132
    (4th Cir. 1994), Evans claims that the
    criminality of a particular prescription can only be shown through the patient’s
    own testimony or expert testimony specifically addressing the patient’s case.
    To permit otherwise would allow the jury to find a particular prescription
    criminal based solely on a pattern or association. In this case, neither Cash,
    Decoteau, nor Roper testified, and Doctor Graves Owen, the Government’s
    medical expert, did not specifically address their cases. So, Evans says, the jury
    had no particularized basis to conclude that the three prescriptions were
    medically illegitimate. Evans bolsters this argument with his second point—
    that his clinic had all the trappings of a legitimate pain-management practice.
    We are unconvinced. Put briefly, our review of the Government’s main
    evidence on the three convictions—the three patient files themselves—leads
    us to conclude that the jury could rationally find that Cash’s, Decoteau’s, and
    Roper’s prescriptions were written without a legitimate medical purpose and
    outside the usual course of professional practice.
    All three patient files have troubling features Owen isolated as
    symptomatic of illegitimate prescribing practices. All three patients are
    Louisianans who came to Evans complaining of a longstanding injury and
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    severe pain. Despite their complaints, no record of any physical examination
    exists—besides a range-of-motion test on Decoteau’s last visit. When they
    started seeing Evans, all three reported that they were already on an opioid
    for the pain. Cash’s prescription sheet was particularly loaded: she came to
    Evans on fentanyl, oxycodone, Ambien, Cymbalta, acetaminophen, Lyrica,
    naproxen, and tramadol, among other things. The prior medical records and
    histories of all three were barebones. Each provided only an MRI, gave no
    indication of how long he or she had been on opioids, and did not state what
    non-opioid alternatives he or she had tried.
    In all three cases, this was enough for Evans to prescribe more than a
    year and a half of Roxicodone along with a mix of other drugs which formed a
    popular drug cocktail. Their dosages were not reduced (Decoteau’s was actually
    bumped up twice—once without even a doctor’s visit). While seeing Evans, no
    patient reported a meaningful abatement of pain. In fact, Decoteau’s reported
    pain got substantially worse on his last two visits, with no documented
    response from Evans. In general, Evans’s notes in each file are illegible,
    cursory (“Any signs of misuse: 0”; “Do benefits outweigh the risks of treatment:
    Y”), or completely missing. The notes from Evans’s employees are also
    extraordinarily repetitive, stating over and over that the patient is doing
    “really good” with stretching and that his or her “pain level is about the same.”
    Each patient also reported concerning feelings and behaviors. Cash
    reported that she often took more pills than prescribed and sometimes had
    mood swings, felt she needed more drugs, and got overwhelmed to the point
    she thought she could not handle things. Decoteau reported that he often felt
    a need for more pills and “seldom” ran out of pills early, took more than he was
    supposed to, or borrowed pills from others. He also reported mood swings,
    anger issues, impatience with doctors, and feeling overwhelmed. Roper
    reported that others sometimes expressed concern about his use of medication
    16
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    No. 17-20158
    and that he seldom ran out of pills early, took more than prescribed, or felt
    consumed by the need to get more. No documented response exists for any of
    these red flags. None of the three received a drug test, and, by the end, all three
    were seeing Evans only once every three months. From these files, the jury
    could reasonably conclude that the particular prescriptions written for Cash,
    Decouteau, and Roper had no legitimate medical purpose or were outside the
    course of Evans’s professional practice.
    Evans’s heavy reliance on Tran Trong Cuong is misplaced. As an out-of-
    circuit case we have not expressly endorsed, it cannot be used to show clear or
    obvious error, the second prong of plain-error review. See United States v.
    Fuchs, 
    467 F.3d 889
    , 901 (5th Cir. 2006) (finding no plain-error when there
    was no “clearly established law in the Fifth Circuit” on the point). Of greater
    significance, the evidence in this case meets the level of particularity the
    Tran Trong Cuong court demanded.
    In Tran Trong Cuong, the Fourth Circuit struck down 80 distribution
    convictions based on prescriptions written for 20 non-testifying 
    patients. 18 F.3d at 1141-43
    . At trial, the Government’s only evidence on the 80 counts
    was a medical expert’s testimony, a summary report prepared by the expert on
    patient files taken from the defendant’s office (not the files themselves), and
    copies of the 80 prescriptions. 
    Id. at 1141.
    The summary report only stated the
    number of visits, what the visits were for, and what was prescribed. 
    Id. The expert
    never examined or interviewed any of the 20 relevant patients, and, on
    direct, he made no mention of the prescriptions they received. 
    Id. On cross-
    examination, the expert admitted that for some of these patients he had “no
    way of judging whether [the prescriptions] were valid or not because there was
    not enough ongoing relationship.” 
    Id. With respect
    to one patient, he admitted
    that the medication given “could be justified” in the abstract, but taken
    together with the pattern of the other cases, it could not be justified. 
    Id. 17 Case:
    17-20158    Document: 00514544493      Page: 18   Date Filed: 07/06/2018
    No. 17-20158
    The Fourth Circuit held that this evidence was insufficient to support
    the 80 distribution convictions. 
    Id. at 1143.
    The court refused to conclude the
    prescriptions were improper “simply because they followed a pattern.”
    
    Id. at 1141.
    Instead, the court expressed concern that the “defendant may have
    been found guilty of some counts by association.” 
    Id. This was
    impermissible,
    per the Fourth Circuit, because the defendant was “entitled to individual
    consideration of every count in [the] indictment by the jury and evidence
    sufficient to convict on each count beyond a reasonable doubt.” 
    Id. at 1142.
          Fourth Circuit cases interpreting Tran Trong Cuong demonstrate that it
    is the evidence’s connection to the particular prescription—not the type of
    evidence—that is key to confirm a distribution conviction against a prescribing
    doctor. In United States v. Singh, the Fourth Circuit explained that “[t]here
    are no specific guidelines concerning what is required to support a conclusion
    that an accused acted outside the usual course of professional practice.” 
    54 F.3d 1182
    , 1187 (4th Cir. 1995) (alteration in original) (quoting United States v.
    August, 
    984 F.2d 705
    , 713 (6th Cir. 1992)). “Rather, the courts must engage in
    a case-by-case analysis of evidence to determine whether a reasonable
    inference of guilt may be drawn from specific facts.” 
    Id. (quoting August,
    984 F.2d at 713). According to the Singh court, the reason Tran Trong Cuong’s
    convictions were reversed was “not because the victims did not testify, but
    rather because their lack of testimony was not replaced by any substantive
    evidence.” 
    Id. at 1188.
    This contrasted with the situation in Singh, where even
    though two of the relevant patients did not testify, the defendant’s sufficiency
    challenge was denied because an expert witness filled in the gaps for those two
    patients. 
    Id. We have
    similarly interpreted Tran Trong Cuong as focusing on the
    evidence’s connection to the particular patient, not the precise type of evidence.
    In United States v. Armstrong, we described the holding in Tran Trong Cuong
    18
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    (without endorsing it) as such: “[E]vidence regarding the particular patient
    visit or treatment giving rise of the § 841 charge should be presented at trial
    in order for a conviction on the charge to withstand a motion for acquittal.”
    
    550 F.3d 382
    , 391 (5th Cir. 2008). We found the evidence particular enough in
    Armstrong because the Government had the relevant patients (who turned out
    to be undercover agents) testify, played recordings of the relevant visits, and
    put on the relevant patients’ medical records. 
    Id. We did
    not, however, hold
    that this level of evidence was necessary for a distribution conviction to
    withstand attack on appeal. See 
    id. Turning back
    to Evans’s case, the Government’s evidence satisfies
    Tran Trong Cuong’s admonition that the particular prescription must be
    medically invalid, not just fit a larger pattern. In this case, the Government
    offered the three relevant patient files, not merely a cursory summary report.
    See Tran Trong 
    Cuong, 18 F.3d at 1141
    . And unlike the Government expert in
    this case, the expert in Tran Trong Cuong specifically testified that he was
    relying on trends rather than specific patient files to find the prescriptions
    medically invalid. See 
    id. Here, Owen
    testified that every file he reviewed—
    which included Cash’s, Decoteau’s, and Roper’s—contained inadequate
    documentation to justify the level of opioids prescribed.
    Evans’s next move is to argue that he generally ran a legitimate pain-
    management clinic. Given his practice’s legitimate trappings, the safeguards
    he had in place, and the various appropriate actions he took, Evans argues that
    any overprescribing was merely negligent and not criminal. To support this
    theory, Evans runs through the various indicia of his practice’s validity.
    According to Evans, he: (1) required MRIs and prescription records; (2) did
    physical examinations; (3) adjusted some patients’ dosage downward and
    rejected others; (4) treated patients for addiction with Suboxone; (5) created
    treatment plans that went beyond prescribing opioids, including massages,
    19
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    stretching, and peg-board therapy; (6) monitored drug abuse via SOAPPs and
    COMMs; and (7) treated real patients with real injuries and real pain. He
    contrasts all this with the typical distribution case, where the doctor might
    never see the patients or hands prescriptions out of a car in a back-alley.
    We address each point below. But the bottom line is this: in light of the
    substantial evidence that Evans ran an illegitimate practice, every fact Evans
    brings to his defense does little to move the needle in his favor. The jury could
    reasonably dismiss each precaution or prudent act Evans cites as either wholly
    inadequate, a vestige of his prior legitimate practice, or in fact a sham designed
    to hide his operation’s nefarious purpose.
    Just a sampling of the circumstantial evidence corroborating this view
    will suffice. Evans routinely prescribed a high dosage of opioids along with
    other drugs which formed a well-known and highly abused drug cocktail.
    Evans wrote the majority of opioid prescriptions for Briargrove which, in turn,
    was Texas’s top opioid distributor. Most of his pain-management patients came
    from Louisiana. These patients started coming when Louisiana tightened its
    pain-medication regulations and stopped coming when Evans’s office was
    raided. Under Evans’s mail-order scheme, his patients would be seen only once
    every three months and would get prescriptions merely for sending in enough
    money. A medical expert’s review of 17 or 18 of Evans’s patient files left the
    impression that all of the patients were really customers. There was also a lot
    of evidence that Evans abused his prescription pad. Both of Evans’s assistants
    admitted that Evans would sign blank prescriptions for them to fill out later—
    a fact corroborated by a stack of signed but otherwise blank prescriptions
    seized from Evans’s office. Rhoda Mann, Evans’s medical assistant, thought
    that the majority of Evans’s patients who received oxycodone were chemically
    dependent and needed opioids to avoid withdrawal.
    20
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    The case of Kimberly Richardson—the relevant patient for the two
    distribution convictions Evans does not challenge—is particularly damaging to
    Evans’s case that his safeguards were adequate or enforced. At trial,
    Richardson testified that after back and neck surgery in the early 2000s, she
    became addicted to pain medications. Her addiction lasted until the mid-2000s,
    when she got clean. Richardson continued to suffer serious pain and started
    seeing Evans in 2010 after hearing about him via word of mouth in Louisiana.
    Richardson’s first visit with Evans lasted five minutes. Despite
    disclosing that she had a prior drug problem, she received a prescription for
    Roxicodone, Lortab, and Valium. Richardson quickly became addicted again.
    When she first started seeing Evans, Richardson would drive to Evans’s
    office every month, where he would see her for two or three minutes. One of
    Richardson’s appointments was caught on video. During the visit (which
    Richardson called typical), Rhoda Mann filled out the prescription and Evans
    signed it. Evans did not physically examine Richardson during the visit, even
    though she complained that the pain from her Lupus was getting worse. (Owen
    would later testify that the symptoms of Richardson’s Lupus could have been
    exacerbated by opioids, causing her greater pain.) In total, Evans saw
    Richardson for less than two minutes.
    Richardson’s monthly dosage of Roxicodone fluctuated. After seeing
    Richardson for a few months, Evans reduced her pill count. Richardson stayed
    on the lower dosage for a few months, but eventually got into a fight with
    Evans, demanding he up her drugs. She told him that if he did not do so, she
    wanted her money back. Following the argument, he bumped her Roxicodone
    prescription up past where it had been before. Richardson thought her new
    dosage was “a lot of medication for anybody” and if she “used all the
    medication,” instead of selling some of it, she “would be in a coma or dead.” At
    one point, her drugs were confiscated by the postal service, and she returned
    21
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    No. 17-20158
    to Evans’s office asking for more. She got another prescription. In sum, the jury
    could reasonably view Richardson’s case as strong evidence that Evans’s
    safeguards were either not tailored to stop drug abuse, dramatically under-
    enforced, or simply a sham.
    Going one by one through the facts Evans marshals in his defense, the
    jury could and did reasonably reject each. Evans’s patients did have to submit
    MRIs and prescription sheets. But without more, Owen explained, such
    medical records are inadequate. They do not reveal the full scope of the past
    treatments. Nor do they document the patients’ full medical history. Thus,
    neither demonstrates that more conservative options were exhausted, a
    prerequisite—according to Owen—before turning to a risky tool of last resort
    like opioids. Nor does Evans’s claim that he performed physical examinations
    inspire much faith. Only one documented examination occurred for the three
    relevant patients over a total of 27 appointments. In any event, the jury could
    credit Owen’s testimony that the only recorded examinations—range-of-
    motion tests—were inadequate, incredible, and performed by staff without
    adequate qualifications.
    Next, Evans did dismiss some patients for things like submitting fake
    MRIs, doctor shopping, and violating patient agreements. He also reduced
    some of his patients’ prescriptions. These dismissals and reductions, however,
    are irrelevant to the legitimacy of Cash’s, Decoteau’s, and Roper’s treatment.
    And the jury could reasonably infer that patients were rejected only when they
    became troublesome and with little thought given to their wellbeing. Take the
    case of one patient that was discharged for injecting her pain medication. She
    was sent on her way with a reduced prescription for Roxicodone and not
    referred to drug treatment. In fact, Clayton could not recall an instance where
    a patient was referred to a drug-rehabilitation program, and only two of
    22
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    Evans’s 956 patients who received oxycodone were ever put on Suboxone to
    treat addiction.
    The jury could reasonably conclude that Evans’s non-opioid based
    treatments—like massages, peg-board therapy, and stretching—were cookie-
    cutter treatment plans that did not validate his simultaneous overprescription
    of opioids. Even if things like massages and stretching help, the jury could
    reasonably credit Owen’s testimony that opioids should be a tool of last, not
    first, resort. And by the end, patients would only receive these allegedly helpful
    services once every three months.
    With respect to the patient agreements, the SOAPPs, and the COMMs,
    the jury could reasonably conclude that these were mere formalities. The risk-
    assessment tools meant little as they were never followed up upon. And self-
    reporting alone may not be enough. As Owen explained, drug tests should be
    imposed for long-term opioid recipients.
    Finally, the fact that Evans’s patients were in real pain and needed real
    help does not show that the strong doses of opioids they all received for a
    sustained period were legitimate. In fact, it shows the opposite. The three
    relevant patients who entrusted their health and care to Evans did not report
    a meaningful abatement in their pain or increase in function. Instead, they
    reported concerning thoughts and feelings about their medication with no
    follow up.
    In sum, all three patient files contain numerous signs of medically
    illegitimate prescribing practices. This all rests atop the strong circumstantial
    evidence that Evans acted outside the usual course of his professional practice.
    Altogether, the record is not “devoid of evidence pointing to guilt,” nor is the
    evidence “so tenuous that a conviction is shocking.” See 
    Suarez, 879 F.3d at 632-33
    (quoting United States v. Phillips, 
    477 F.3d 215
    , 219 (5th Cir. 2007)).
    23
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    B.
    Evans next attacks the sufficiency of the evidence on all five of his
    convictions for money laundering under 18 U.S.C. § 1957. We reject his
    challenge as we cannot say that letting his convictions stand would be plain
    error.
    Section 1957(a) makes it a crime knowingly to “engage in a monetary
    transaction in criminally derived property of a value greater than $10,000 and
    is derived from” certain specified crimes. 18 U.S.C. § 1957(a). Broken down,
    the crime has three elements: “(1) property valued at more than $10,000 that
    was derived from a specified unlawful activity, (2) the defendant’s engagement
    in a financial transaction with the property, and (3) the defendant’s knowledge
    that the property was derived from unlawful activity.” 
    Fuchs, 467 F.3d at 907
    .
    “[C]riminally derived property” is “‘property constituting, or derived from,
    proceeds obtained from a criminal offense,’ such as drug trafficking.” United
    States v. Alaniz, 
    726 F.3d 586
    , 602 (5th Cir. 2013) (quoting 18 U.S.C.
    § 1957(f)(2)).
    In this case, the five withdrawals the Government charged all emanated
    from a single bank account—Evans’s account with Amegy Bank. This account
    was commingled—that is, it held Evans’s clean and tainted money. “Obviously,
    when tainted money is mingled with untainted money in a bank account, there
    is no longer any way to distinguish the tainted from the untainted because
    money is fungible.” United States v. Davis, 
    226 F.3d 346
    , 357 (5th Cir. 2000).
    To deal with this “commingling problem,” we have adopted a clean-funds-out-
    first rule. See 
    id. Under the
    clean-funds-out-first rule, the defendant is deemed
    to first withdraw her clean funds in a commingled account before reaching into
    tainted funds. See id.; cf. United States v. Poole, 
    557 F.2d 531
    , 535-36 (5th Cir.
    1977) (reversing a conviction for interstate transfer of funds obtained by fraud
    based on use of commingled funds because the check in question was for less
    24
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    No. 17-20158
    than the amount of clean funds in the account). Thus, “where an account
    contains clean funds sufficient to cover a withdrawal, the Government can not
    prove beyond a reasonable doubt that the withdrawal contained dirty money.”
    United States v. Loe, 
    248 F.3d 449
    , 467 (5th Cir. 2001).
    But this poses a problem when a defendant makes several withdrawals,
    each individually for less than the clean-fund total in his account. See 
    Davis, 226 F.3d at 357
    . Viewed individually, a particular withdrawal would only use
    clean money, even though in aggregate the defendant would have had to dip
    into tainted funds. See 
    id. To cope
    with this problem, we aggregate the
    transactions—“when the aggregate amount withdrawn from [the] account . . .
    exceeds the clean funds, individual withdrawals may be said to be of tainted
    money, even if a particular withdrawal was less than the amount of clean
    money in the account.” See 
    Fuchs, 467 F.3d at 907
    (alterations in original)
    (quoting 
    Davis, 226 F.3d at 357
    ). So, under this aggregation rule, the
    Government need only show aggregate withdrawals in excess of $10,000 above
    the amount of clean funds in the account to validate a money-laundering
    conviction. See 
    Davis, 226 F.3d at 357
    ; see also 
    Fuchs, 467 F.3d at 907
    (“Because the total amount of the financial transactions ($4 million) exceeded
    the amount of clean funds ($3 million), the government sufficiently
    demonstrated financial transactions involving the proceeds of unlawful
    activity in violation of § 1957.”).
    Turning to the case at hand, the Government’s theory of money
    laundering was that Evans used the ill-gotten proceeds of his practice to invest
    in a retirement account and to purchase real estate. These charged
    transactions were based on withdrawals from Evans’s bank account with
    Amegy. To trace the flow of Evans’s money and prove this theory, the
    Government called an expert who had reviewed the patient files seized from
    Evans’s office. This expert reported that of the roughly 2,000 patient files
    25
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    seized, 956 patients received Schedule II prescriptions. The expert called these
    956 patients Evans’s “Schedule II patients.” The expert then matched copies of
    prescriptions in the patient files with money orders patients delivered to Evans
    as well as daily monetary receipts and deposit slips. With this raw data, the
    expert created a database tracking the number of Schedule II prescriptions
    going out and the flow of money in. From 2010 to 2012, Evans brought in over
    $2.4 million in cash, money orders, and checks from his Schedule II patients.
    While Evans received income from other sources over that time period, the
    expert was able to segregate the money Evans received from Schedule II
    patients.
    The expert next looked into where this $2.4 million went, creating charts
    showing the flow of money in and out of Evans’s various accounts. Evans had
    two main bank accounts (one with Chase and another with Amegy), and one
    main investment account with Raymond James. The expert tracked deposits,
    withdrawals, and monthly balances from the Chase account beginning in
    January 2010 until Evans closed it in October 2011. At the start of 2010, most
    of the money coming in was from workers’ compensation payments. But over
    time, payments from Schedule II patients became the predominant source of
    deposits. By September 2011, most deposits were from Schedule II patients.
    The expert then did a similar analysis of the Amegy account, which Evans
    opened in August 2011. In aggregate, a little more than $1.13 million was
    deposited into the Amegy account. Of that, “the majority, if not almost all”
    came from Schedule II patients. In turn, an “overwhelming majority” of
    Schedule II payments were made from patients from Louisiana, who made up
    805 of the 956 Schedule II patients. The expert also tracked aggregate
    withdrawals from the Amegy account, concluding aggregate withdrawals were
    $221.13 shy of aggregate deposits.
    26
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    The expert then testified to the five money-laundering transactions
    charged in the indictment. Evans was charged with making two deposits into
    his Raymond James retirement account (one for $14,439 and another for
    $15,000) and three withdrawals from his Amegy account ($64,000, $59,000,
    and $48,663) to buy some real estate. The expert confirmed that these five
    charged transactions occurred, that the two charged deposits into the Raymond
    James account were based on checks drawn from Evans’s Amegy account, and
    that the three charged withdrawals from Evans’s Amegy account were used to
    purchase real estate.
    On appeal, Evans quarrels with the Government’s method. He points out
    that the Government’s expert assumed that all Schedule II prescriptions were
    medically illegitimate and thus any proceeds from them were tainted. But,
    according to Evans, this conclusion cannot be rationally drawn from the
    evidence. The Government’s medical expert only reviewed 17 or 18 patient
    files, far shy of the 956 Schedule II patients. Other Government witnesses
    admitted that some of Evans’s patients might have been legitimate. And Evans
    even called one of his former patients, who swore that Evans’s prescriptions
    helped him. Evans also argues that the Government failed to calculate his
    irrefutably clean money, which came from patients not receiving pain-
    management therapy—like his car-accident, workers’ compensation, and
    cancer patients. Evans synthesizes his argument by claiming that the
    Government asked the jury to do a math formula without evidence on a key
    variable—total clean money. The jurors could not know if the aggregate money
    withdrawn was more than the total clean funds because they had no idea how
    much of Evans’s money was tainted and how much was clean.
    We are unconvinced. It is true that the record does not reveal exactly
    how much of Evans’s money was tainted. But despite this, the jury could
    27
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    rationally find that a sufficient amount of his practice’s proceeds were tainted
    to justify all five money-laundering convictions.
    The reason for our confidence is that the amount of tainted funds the
    Government needed to prove up was tiny relative to the amount of money
    Evans’s practice brought in and how much went out. Recall that Evans’s
    aggregate deposits and withdrawals from Amegy were both a little over
    $1.13 million. The difference between aggregate deposits and withdrawals was
    $221.13. Under the clean-funds-out-first rule, this gives Evans a small $221.13
    buffer of un-touched funds. Under the aggregation rule, to prove all five money-
    laundering counts, the Government needed to show that more than $50,221.13
    of the $1.13 million in deposits was criminally derived. That would be enough
    to convict on all five counts as it would satisfy § 1957(a)’s $10,000 statutory
    threshold five-times over while accounting for the $221.13 buffer of
    untransferred funds.
    Given this low requisite threshold—just $50,221.13 of $1.13 million, or a
    little less than five percent—Evans faces an uphill battle to show his money-
    laundering convictions were plainly erroneous. True, Evans’s Amegy account
    contained indisputably clean proceeds from non-Schedule II patients. But the
    Government’s expert, who traced the flow of prescriptions and money orders,
    said that most, if not all, of Evans’s money in his Amegy account came from
    Schedule II patients. Also true, the record does not reveal precisely how many
    Schedule II prescriptions were medically invalid. But from the evidence we
    have discussed in detail on Evans’s challenge to his distribution convictions, a
    rational juror could conclude that the percentage of Evans’s money coming in
    from bogus prescriptions was over five percent. It may be the case that trends
    and tendencies alone cannot support a conviction on a particular distribution
    count. See Tran Trong 
    Cuong, 18 F.3d at 1141
    -43. But here, the Government
    was not required to show that any particular prescription was criminal, just
    28
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    five percent of the total. We cannot say that the record is “devoid of evidence
    pointing to guilt,” or that the evidence is “so tenuous that a conviction is
    shocking.” See 
    Suarez, 879 F.3d at 632-33
    (quoting 
    Phillips, 477 F.3d at 219
    ).
    C.
    Evans’s third and final sufficiency-of-the-evidence challenge goes to his
    eight mail-fraud convictions under 18 U.S.C. § 1341. Relatedly, he attacks the
    legal sufficiency of indictment on those same mail-fraud counts. Again, we
    review the attacks for plain error, 1 and, once again, conclude there was none.
    1 As explained previously, Evans did not raise a properly timed motion for acquittal,
    and thus our review of his sufficiency-of-the-evidence challenge is for plain error.
    See 
    Jimenez, 509 F.3d at 690
    . Similarly, on Evans’s sufficiency-of-the-indictment challenge,
    because Evans “failed to object below, the appropriate standard of review is plain error.”
    See United States v. Hoover, 
    467 F.3d 496
    , 498 (5th Cir. 2006). An extended digression will
    show this.
    Following the grand jury’s return of the original indictment, Devido, Evans’s
    codefendant who eventually pleaded guilty, moved to dismiss the mail-fraud counts. (While
    this motion is not in the record, we may take judicial notice of it. See United States v. Mills,
    555 F. App’x 381, 387 n.2 (5th Cir. 2014) (per curiam); ITT Rayonier Inc. v. United States,
    
    651 F.2d 343
    , 345 n.2 (5th Cir. Unit B July 1981)). Devido argued that the mail-fraud counts
    were legally infirm because the Government had not identified any “victims” whose property
    interests were harmed by any misrepresentation made by the defendants. Evans moved to
    join Devido’s motion, arguing that the legal inadequacy Devido identified applied equally to
    him. The district court, in a brief order, denied Evans’s motion to join.
    A little over two months later, a superseding indictment was returned. It re-alleged
    the manner and means from the original indictment, but added that Evans “failed to
    maintain proper medical records and to provide patients with a proper standard of care”
    under Texas and federal law. (The original indictment only charged that Evans would write
    prescriptions “after performing minimal or no medical examination.”) After this superseding
    indictment was returned, Evans moved to dismiss it. While Evans raised many arguments
    in this motion, on appeal he does not argue that any of them preserved his current argument.
    Instead, he claims that his attempt to join Devido’s motion to dismiss the original indictment
    preserved his claim for appeal.
    We conclude that Evans’s attempt at joining did not preserve his present attack on
    the indictment. Typically, a defendant must bring his own objections to preserve them.
    See United States v. Harris, 
    104 F.3d 1465
    , 1471 (5th Cir. 1997) (“[T]he objection of one
    defendant, in and of itself, does not preserve the appellate rights of other defendants.”). A
    defendant may join the motions of her codefendants to preserve error, but only if the
    Government has no valid objection and the district court allows it. See United States v.
    Whittington, 269 F. App’x 388, 400 (5th Cir. 2008) (per curiam); cf. United States v. Bernal,
    29
    Case: 17-20158       Document: 00514544493          Page: 30     Date Filed: 07/06/2018
    No. 17-20158
    Mail fraud under 18 U.S.C. § 1341 has three elements: “(1) a scheme to
    defraud; (2) use of the mails to execute that scheme; and (3) the specific intent
    to defraud.” United States v. Lucas, 
    516 F.3d 316
    , 339 (5th Cir. 2008) (quoting
    United States v. Dotson, 
    407 F.3d 387
    , 391-92 (5th Cir. 2005)). The action here
    pertains to the first and last elements—“scheme to defraud” and “intent to
    defraud”—as Evans does not contest his use of the mails.
    We begin by defining our terms. “Scheme to defraud” is tricky to define,
    “but it includes any false or fraudulent pretenses or representations intended
    to deceive others in order to obtain something of value, such as money, from
    the [entity] to be deceived.” United States v. Saks, 
    964 F.2d 1514
    , 1518
    (5th Cir. 1992) (internal citation omitted). Such falsity must be material,
    see United States v. Caldwell, 
    302 F.3d 399
    , 409 (5th Cir. 2002), that is, it must
    have “a natural tendency to influence, or [be] capable of influencing, the
    decision of the decisionmaking body to which it was addressed,” Neder v.
    United States, 
    527 U.S. 1
    , 16 (1999) (quoting United States v. Gaudin, 
    515 U.S. 506
    , 509 (1995)). We have held in the context of a prosecution for making false
    statements that this “natural tendency” test “is an objective one focused on
    whether the statement is ‘of a type capable of influencing a reasonable decision
    maker.’” United States v. Abrahem, 
    678 F.3d 370
    , 375 (5th Cir. 2012) (quoting
    
    814 F.2d 175
    , 182 (5th Cir. 1987) (holding a defendant’s adoption of his codefendant’s
    objection to a jury instruction preserved the error when the Government failed to “point[] to
    some sound reason for refusing” it, the district court did not “refus[e] to permit such
    adoption,” and no “other exceptional circumstances” indicated the adoption “misled the
    district court or opposing counsel”).
    Here, the district court disallowed joinder, so Devido’s argument cannot preserve
    Evans’s present challenge. Further, even if we granted that Evans properly joined Devido’s
    motion, Evans still would not have preserved his present challenge. Devido’s motion attacked
    the original indictment’s sufficiency, not the superseding one which added key details to the
    nature of the charged fraud. And as Evans did challenge the superseding indictment (just on
    other grounds), he cannot now complain that he had no opportunity to raise his present
    objection. Cf. Fed. R. Crim. P. 51(b) (“If a party does not have an opportunity to object to a
    ruling or order, the absence of an objection does not later prejudice that party.”).
    30
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    No. 17-20158
    United States v. McBane, 
    433 F.3d 344
    , 351 (3d Cir. 2005)). The test focuses on
    the “intrinsic qualities” of the statement itself and “transcend[s] the immediate
    circumstances in which it is offered.” 
    Id. at 376
    (quoting 
    McBane, 433 F.3d at 351
    ). Thus, a crazed man demanding to see a patient being kept under guard
    by federal agents makes a materially false statement when he tells the agents
    he is the patient’s lawyer. 
    Id. at 371-73,
    376. Although the circumstances dispel
    any chance that the agents might buy the lie, the representation that one is a
    lawyer “is of a type that would naturally tend to influence or is capable of
    influencing the decision maker.” 
    Id. at 376
    .
    Moving along, “intent to defraud” requires “an intent to (1) deceive, and
    (2) cause some harm to result from the deceit.” United States v. Moser, 
    123 F.3d 813
    , 820 (5th Cir. 1997) (quoting United States v. Jimenez, 
    77 F.3d 95
    , 97 (5th
    Cir. 1996)). “A defendant ‘acts with the intent to defraud when he acts
    knowingly with the specific intent to deceive for the purpose of causing
    pecuniary loss to another or bringing about some financial gain to himself.’”
    United States v. Umawa Oke Imo, 
    739 F.3d 226
    , 236 (5th Cir. 2014) (quoting
    United States v. Akpan, 
    407 F.3d 360
    , 370 (5th Cir. 2005)); accord United States
    v. St. Gelais, 
    952 F.2d 90
    , 96 (5th Cir. 1992).
    Before we can turn to Evans’s particular attacks, we must elaborate on
    the standard we use to judge indictments. The point of an indictment “is to
    inform a defendant of the charge against him.” United States v. Hoover,
    
    467 F.3d 496
    , 499 (5th Cir. 2006). Thus, “[p]ractical, not technical,
    considerations govern” our review, and the test “is ‘not whether the indictment
    could have been framed in a more satisfactory manner, but whether it conforms
    to minimal constitutional standards.’” United States v. Chaney, 
    964 F.2d 437
    ,
    446 (5th Cir. 1992) (footnote omitted) (quoting United States v. Webb, 
    747 F.2d 278
    , 284 (5th Cir. 1984)). Those minimum constitutional standards are
    threefold: the indictment must (1) have the essential elements of the offense
    31
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    No. 17-20158
    charged for each count, (2) describe the elements of the offense with
    particularity, and (3) be specific enough to protect the defendant from
    subsequent prosecution for the same offense. See United States v. Simpson,
    
    741 F.3d 539
    , 547 (5th Cir. 2014).
    As previewed, Evans’s attack goes to the particularity with which the
    indictment charged the “intent to defraud” and “scheme to defraud” elements
    of mail fraud. His argument with respect to the first—intent—fails straight
    out of the gate as we have held that intent “need not be specifically charged in
    the indictment.” See United States v. Ratcliff, 
    488 F.3d 639
    , 644 n.4
    (5th Cir. 2007). With respect to the latter—“scheme to defraud” and its
    requirement of materiality—our caselaw holds that the indictment need not
    “establish materiality,” see 
    Hoover, 467 F.3d at 500
    , but must simply raise an
    “inference,” see 
    Caldwell, 302 F.3d at 409
    . “[T]he proper inquiry is whether the
    allegation [in the indictment] is ‘potentially capable of being proved material
    by the government at trial,’ and whether the allegation is sufficient to support
    an inference of materiality.” United States v. Bieganowski, 
    313 F.3d 264
    , 286
    (5th Cir. 2002) (quoting United States v. McGough, 
    510 F.2d 598
    , 602 (5th Cir.
    1975)).
    Evans’s twin-attacks on the indictment and the sufficiency of evidence
    at trial share a common core. His basic argument underlying both challenges
    is that the indictment alleged and evidence showed that his patients got
    exactly what they wanted—opioids and other drugs. Thus, Evans’s false
    representations that the drugs were prescribed for a medically legitimate
    purpose could not be a material falsehood—i.e., one that might influence his
    patients. Nor could he have intended to defraud his patients. They got the
    benefit of the illicit deal they struck.
    We reject both arguments. With respect to Evans’s attack on materiality,
    the indictment raised an inference and the evidence allowed the jury
    32
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    No. 17-20158
    reasonably to conclude that Evans’s false representation—that he was
    following the proper standard of care when prescribing—was material. Such a
    falsehood would have a “natural tendency” to influence his patients’ decision
    making. See 
    Neder, 527 U.S. at 16
    . A reasonable person faced with the reality
    that his doctor is prescribing powerful opioids without a medicinal purpose
    might find a new doctor. See 
    Abrahem, 678 F.3d at 375
    . 2 While the “immediate
    circumstances” do not indicate that the four particular patients named in the
    mail-fraud counts would have been concerned about the quality of care they
    received, the “intrinsic qualities” of the representation are surely material.
    See 
    id. at 376.
    The representation that one is a doctor prescribing needed
    medicine is “of a type that would naturally tend to influence” patients. See 
    id. Turning to
    the intent element, the evidence at trial was enough to allow
    the jury to conclude that Evans’s misrepresentations about his prescription
    writing practices were intentional and that he contemplated that “some harm”
    would arise from these misrepresentations. See 
    Moser, 123 F.3d at 820
    . The
    jury heard evidence that Evans’s overprescribing practices caused some
    patients to get addicted, fed others’ preexisting addictions, and at the very least
    denied them the proper medical care they paid for. 3 And even if Evans thought
    he was ultimately helping his patients, the purpose of his deception was
    certainly to bring “about some financial gain to himself.” See Umawa Oke 
    Imo, 739 F.3d at 236
    (quoting 
    Akpan, 407 F.3d at 370
    ).
    2 We do not wish to imply that a representation is only material if a reasonable person
    would be influenced by it. Our caselaw makes clear that “a statement could indeed be
    material, even though only an unreasonable person would rely on it, if the maker knew or
    had reason to know his victim was likely so to rely.” 
    Davis, 226 F.3d at 358-59
    .
    3 Evans does not argue that these types of harm would not constitute a harm to his
    patients’ property rights. Thus, we need not decide whether these types of injury constitute
    “harm to the property rights of the victim.” See United States v. Leonard, 
    61 F.3d 1181
    , 1187
    (5th Cir. 1995).
    33
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    No. 17-20158
    Evans argues that the particular harm he may have contemplated—
    getting his patients hooked, feeding their addictions, or denying them proper
    care—was not the type of harm required to show intent to defraud. Rather, he
    argues that “the harm contemplated must affect the very nature of the bargain
    itself.” See United States v. Starr, 
    816 F.2d 94
    , 98 (2d Cir. 1987); United States
    v. Regent Office Supply Co., 
    421 F.2d 1174
    , 1180 (2d Cir. 1970). Evans argues
    that if he really was a drug dealer, his patients got the benefit of the bargain
    they struck with him. But, we have not adopted the rule from Starr and Regent
    Office, nor have many other circuits. See United States v. Bereano, 
    161 F.3d 3
    ,
    
    1998 WL 553445
    , at *3 & n.5 (4th Cir. 1998) (unpublished table decision)
    (remarking that the circuits are split over whether any contemplation of harm
    is even necessary); United States v. Butler, 
    704 F. Supp. 1351
    , 1354 (E.D. Va.
    1989) (noting that the rule from Starr “is in opposition to the rule in the
    majority of the Circuits”). Evans thus cannot rely upon Starr to show a “clear
    or obvious” error. See 
    Fuchs, 467 F.3d at 901
    . 4
    To recap, we discern no plain error, whether by lack of evidence or defects
    in the indictment, with respect to any of Evans’s convictions. We now turn to
    a pair of evidentiary rulings Evans contests on appeal.
    III.
    Evans asks us to review and reject two evidentiary rulings made by the
    district court. First, he contends that the district court improperly allowed
    Kristi Smith and Donna Epley—the two dental assistants who worked in
    Evans’s building—to say that they suspected Evans ran a pill mill. Per Evans,
    this testimony was inadmissible under Federal Rule of Evidence 602 as pure
    speculation, not based on Smith or Epley’s personal knowledge. Next, Evans
    4  As we conclude the indictment and evidence were sufficient for the mail-fraud
    convictions to stand, we do not address Evans’s claim that legal errors in the mail-fraud
    counts tainted his conspiracy conviction.
    34
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    No. 17-20158
    argues that Chris Helmke’s letter to David Devido—Helmke’s boss at
    Briargrove Pharmacy at the time—was hearsay and thus inadmissible under
    Rule 802. In that letter, Helmke accused Evans of running a pill mill and
    described Evans’s patients as “unsavory.” For both attacks, Evans claims the
    admission of the challenged evidence influenced the result of what he thinks is
    a close case.
    We review the two rulings for abuse of discretion. See United States v.
    Lockhart, 
    844 F.3d 501
    , 512 (5th Cir. 2016). If error occurred, it can be excused
    if harmless. See United States v. El-Mezain, 
    664 F.3d 467
    , 525-26 (5th Cir.
    2011); see also Fed. R. Crim. P. 52(a). Here, because the alleged errors are
    nonconstitutional, such errors are harmless unless they had a “substantial and
    injurious effect or influence in determining the jury’s verdict.” See 
    El-Mezain, 664 F.3d at 526
    (quoting United States v. Lowery, 
    135 F.3d 957
    , 959 (5th Cir.
    1998) (per curiam)). “Under this standard, we ask ‘whether the error itself had
    substantial influence’ on the jury in light of all that happened at trial; if we are
    ‘left in grave doubt, the conviction cannot stand.’” 
    Id. (quoting Kotteakos
    v.
    United States, 
    328 U.S. 750
    , 765 (1946)).
    We consider each of Evans’s evidentiary challenges in turn, starting with
    Smith and Epley’s opinion testimony and then moving to Helmke’s letter. We
    ultimately reject both, finding no error or harm from the first and no harm
    from the second.
    A.
    “A witness’s testimony,” under Federal Rule of Evidence 602, “must be
    based on personal knowledge.” 
    Id. at 495.
    “Personal knowledge can include
    inferences and opinions, so long as they are grounded in personal observation
    and experience.” United States v. Cantu, 
    167 F.3d 198
    , 204 (5th Cir. 1999)
    (quoting United States v. Neal, 
    36 F.3d 1190
    , 1206 (1st Cir. 1994)). Similarly,
    under Rule 701, a lay witness may state his ultimate opinion, provided that
    35
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    No. 17-20158
    opinion is “based on personal perception,” “one that a normal person would
    form from those perceptions,” and “helpful to the jury.” United States v. Ebron,
    
    683 F.3d 105
    , 136-37 (5th Cir. 2012). Such opinions “must be the product of
    reasoning processes familiar to the average person in everyday life.” 
    Id. (quoting United
    States v. Yanez Sosa, 
    513 F.3d 194
    , 200 (5th Cir. 2008)).
    Here, Smith and Epley’s shared opinion that Evans ran a pill mill was
    “based on [their] personal knowledge,” and therefore admissible. See El-
    
    Mezain, 664 F.3d at 495
    . Their conclusion was based on over two years of
    observations, which included: a major influx of people from Louisiana soon
    after Louisiana tightened its regulations, the fact that some of the newcomers
    were disheveled and unhygienic, and that some of the newcomers would arrive
    early, loiter, and act strangely. Epley said that some of the new people looked
    impaired and addicted, and she saw a person waving a prescription, saying “I
    got it.” The pair’s search through Evans’s trash revealed prescriptions, letters
    requesting prescriptions, and a flyer explaining how to get prescriptions and
    medication via mail. They saw that Evans’s office was not heavily trafficked on
    the one day when prescriptions were not given out. Smith testified that after a
    raid on Evans’s office, the flow of people from Louisiana slowed down. In total,
    these observations would naturally lead a person to suspect that the doctor’s
    office next door might have transitioned into a drug front.
    True, Smith and Epley’s opinions were not drawn from the patient charts
    or what happened in the examination room. But they were not required to be.
    Instead, their opinions were properly drawn from commonsensical inferences
    a “normal person would form” based on years of observations. See 
    Ebron, 683 F.3d at 137
    . This is not a case where a witness forms an opinion based on
    hearsay rather than personal observation. Cf. United States v. $92,203.00 in
    U.S. Currency, 
    537 F.3d 504
    , 508 (5th Cir. 2008). Nor is it one where a witness
    fancifully speculates. Cf. Visser v. Packer Eng’g Assocs., Inc., 
    924 F.2d 655
    , 659
    36
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    No. 17-20158
    (7th Cir. 1991) (en banc). Thus, admission of Smith and Epley’s ultimate
    opinion—that Evans ran a pill mill—was proper.
    But even if it was not, such error was harmless. Smith and Epley’s
    properly admitted testimony of their observations alone would naturally lead
    the jury to infer that Evans ran a pill mill. Cf. 
    El-Mezain, 664 F.3d at 526
    (finding error harmless when the improperly admitted evidence was
    cumulative). And viewed in relation to “the entire trial proceedings”—namely,
    the evidence of what happened in the examination room—Smith and Epley’s
    comments were not prejudicial. See 
    id. To prove
    Evans’s guilt, the Government:
    called two patients to testify that Evans’s appointments were cursory, played
    a video of one of those cursory appointments, and put on patient charts and
    expert testimony detailing those charts’ deficiencies. In the end, even if Smith
    and Epley’s testimony had been improperly admitted, there is no “reasonable
    possibility” that it “contributed to the conviction.” See 
    El-Mezain, 664 F.3d at 526
    (quoting United States v. Williams, 
    957 F.2d 1238
    , 1242 (5th Cir. 1992)).
    We next consider Helmke’s letter and conclude that its admission, even
    if erroneous, was harmless.
    B.
    Our analysis of Evans’s challenge to Helmke’s letter will be brief.
    Assuming arguendo that Helmke’s letter was inadmissible hearsay, its
    admission was nevertheless harmless. As explained above, the record contains
    substantially stronger evidence of Evans’s illegitimate practice than Helmke’s
    letter. Accordingly, we cannot conclude the letter’s admission had a
    “substantial and injurious effect or influence” on the jury’s verdict. See El-
    
    Mezain, 664 F.3d at 526
    (quoting 
    Lowery, 135 F.3d at 959
    ).
    Having decided that neither of Evans’s evidentiary challenges is valid,
    we move to his last argument—that his Confrontation Clause rights were
    compromised. We determine this claim fails as well.
    37
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    IV.
    Evans claims that the district court violated his Confrontation Clause
    rights by refusing to permit cross-examination into a target letter Brenda
    Clayton—one of Evans’s medical assistants and a Government witness—
    received from the Government. The Government counters by arguing that the
    district court’s limit on cross-examination was constitutionally permissible,
    and, either way, any violation was harmless. We assume without deciding that
    the limit violated the Confrontation Clause, but hold that any potential error
    was harmless.
    From the record, it appears that Clayton was a very nervous witness. On
    direct, after a line of questioning where Clayton swore that she did not see
    patients come in early, loiter, or dress inappropriately, she teared up and the
    district court ordered a break. During the break, the court questioned Clayton’s
    lawyer about her emotional status (outside the presence of the jury), remarking
    that she seemed “a little tender.” Her lawyer explained that Clayton cried
    every time they met. The prosecution then requested to have Clayton declared
    a hostile witness, a request the court denied.
    Back on direct, the prosecutor restarted by apologizing for upsetting
    Clayton. Clayton confirmed that she had spoken with the prosecutor three
    times before the trial. The prosecutor continued his direct examination by
    telling her (a total of three times during his direct) that she had done nothing
    wrong and was not in trouble.
    The next day of trial, near the end of Clayton’s cross-examination,
    Clayton confirmed she had received a letter from the Government stating that
    she was “a target of a federal grand jury investigation.” (A “target,” per the
    United States Attorneys’ Manual, is “a person as to whom the prosecutor or
    38
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    No. 17-20158
    the grand jury has substantial evidence linking him or her to the commission
    of a crime and who, in the judgment of the prosecutor, is a putative defendant.”
    U.S. Dep’t of Justice, United States Attorneys’ Manual § 9-11.151.) Before
    Clayton could answer, the Government objected based on relevance. After
    hearing from the defense, the court initially upheld the relevance objection and
    directed the jury to disregard the question. Later, during a sidebar, the court
    gave the defense another crack at making its case.
    The defense noted that the day before, Clayton was a fragile and
    tentative witness. From this, the jury “could infer that her demeanor was
    caused in part by the fact that she was testifying against her former boss.” To
    bolster this inference, the defense pointed out that the prosecution reassured
    her that the Government did not think she had done anything wrong. Per the
    defense, this was an effort to make the jury believe the Government had no
    criminal interest in her, when in fact the Government had previously sent her
    a target letter. Based on this, the defense argued “there was a misimpression
    left with the jury” which the “defense was entitled” to correct by bringing “the
    full picture of the fact that she was testifying under a target letter.” Bringing
    this fact to light might explain why Clayton was not a model witness. This did
    not sway the district court, and it reconfirmed its prior ruling.
    On appeal, Evans claims that the district court’s ruling violated his Sixth
    Amendment right under the Confrontation Clause to expose Clayton’s
    potential motive to “shad[e her] testimony in an effort to please the
    prosecution” so as to avoid future prosecution. See Greene v. Wainwright, 
    634 F.2d 272
    , 276 (5th Cir. Jan. 1981); cf. Davis v. Alaska, 
    415 U.S. 308
    , 317-18
    (1974) (protecting questioning about “undue pressure” based on the witness’s
    “possible concern that he might be a suspect in the investigation”); United
    States v. Croucher, 
    532 F.2d 1042
    , 1046 (5th Cir. 1976) (protecting questioning
    39
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    No. 17-20158
    of “bias and prejudice stemming from criminal charges which could still be
    pursued against” the witness).
    Even assuming a Confrontation Clause violation, any such violation was
    harmless. Our harmless error analysis for a Confrontation Clause violation is
    informed by five nonexclusive factors originally set forth by the Supreme Court
    in Delaware v. Van Arsdall:
    (1) “the importance of the witness’ testimony in the prosecution’s
    case”; (2) “whether the testimony was cumulative”; (3) “the
    presence or absence of evidence corroborating or contradicting the
    testimony of the witness on material points”; (4) “the extent of
    cross-examination otherwise permitted”; and (5) “the overall
    strength of the prosecution’s case.”
    United States v. Jimenez, 
    464 F.3d 555
    , 564 (5th Cir. 2006) (quoting Delaware
    v. Van Arsdall, 
    475 U.S. 673
    , 684 (1986)). This “harmless-error analysis first
    requires us to ‘assum[e] that the damaging potential of the cross-examination
    [was] fully realized.’” 
    Id. at 563
    (alteration in original) (quoting Van 
    Arsdall, 475 U.S. at 684
    ). We look at each Van Arsdall factor in turn, considering each
    de novo. See 
    id. at 558.
          The first three Van Arsdall factors circle around a related set of
    questions. Was Clayton’s testimony important? Unique? Non-cumulative?
    Otherwise uncorroborated? See Van 
    Arsdall, 475 U.S. at 684
    . We determine
    these factors on balance favor the Government.
    At first blush, Clayton’s testimony could seem crucial. She had been
    inside the examination room and witnessed how Evans handled his patients
    there. She was an “insider,” unlike any of the Government’s other witnesses.
    But her testimony largely did not touch on the key issue on the distribution
    counts—whether the particular charged prescriptions were medically
    legitimate. The Government showed the deficiency of Evans’s treatment of
    those particular patients mainly by calling one of the patients, putting on a
    medical expert, and presenting the patients’ files.
    40
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    What is more, numerous independent sources corroborated the basic
    scheme—that Evans would accept money orders by mail and in exchange
    disburse prescriptions to Briargrove Pharmacy. On top of Clayton’s testimony,
    the prosecution had at least four witnesses describe the scheme—including
    David Devido, Rhoda Mann, and two patients—and put on a flyer found in
    Evans’s trash which laid out the basics of the scheme. Other parts of Clayton’s
    story were also well corroborated. The Government introduced several
    prescriptions Clayton confirmed she wrote out, several patient letters
    requesting prescriptions with accompanying money orders, patient files with
    money orders and matching prescriptions inside, several otherwise blank
    prescriptions signed by Evans found in the patient files, and a pad of 29 pre-
    signed prescriptions.
    The Government did refer to Clayton’s testimony in opening and closing.
    But the Government also emphasized the testimony of several other witnesses;
    the physical evidence, including the patients’ charts, the flyer, the pre-signed
    prescriptions, and the recording of Richardson’s appointment; the money-order
    scheme; and the large number of prescriptions going out and vast sum of money
    coming in until the raid.
    Plus, the testimony of the other insider—Rhoda Mann—was more
    devastating to Evans’s case. Mann admitted that Evans kept blank
    prescriptions for her to fill out so that patients would not go into withdrawal
    when he left town. She added that she thought the majority of Evans’s patients
    on opioids were chemically dependent. 5 Evans is able to pinpoint a single fact
    5 Evans’s response—that Mann also shaded her testimony because of a target letter
    she received—is unpersuasive. Mann was a defense witness. Evans called her, directly asked
    her if she filled out some prescriptions, directly asked her if Evans kept pre-signed
    prescriptions, and did not impeach her when she responded yes to both questions. And Evans
    never sought to impeach Mann by questioning her about the target letter. This is all a strong
    indication that the underlying facts were so well established that the defense was willing to
    41
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    that only Clayton testified to—that she would fill out prescriptions for
    returning patients before Evans had even seen them. Though this was strong
    evidence against Evans, in light of the numerous sources that confirmed that
    Evans pre-signed prescriptions and made them available for his assistants, it
    does not make a measurable difference.
    On the fourth Van Arsdall factor—the extent of the cross-examination
    allowed—neither party gets much traction. Evans was permitted to cross-
    examine Clayton at length, but not about her potential motive to shade her
    testimony.
    On the fifth and last Van Arsdall factor—the overall strength of the
    Government’s case—we find that it favors the Government. Our prior review
    of the evidence from the sufficiency challenges confirms that the Government’s
    case was robust and multidimensional. It included strong circumstantial
    evidence—the flood of patients after the Louisiana clinics closed, the explosion
    of prescriptions which abated after the raid, and the money-orders-for-drugs-
    by-mail scheme. It included strong direct evidence that Evans was churning
    out prescriptions without medical need—the testimony of two patients and the
    files of many more who received extended periods of opioids with little else
    being done to alleviate their pain or underlying condition. And, as we
    previously discussed in the sufficiency section, the Government’s evidence
    strongly supported the conclusion that the trappings of Evans’s practice were
    wholly ineffective or simply a sham.
    In sum, any alleged Confrontation Clause violation was harmless.
    *     *     *
    spot the Government that they occurred. And, either way, Mann’s motive to shade her
    testimony to favor the Government would be transparent to the jury, whether they heard
    about the target letter or not. Mann was a defense witness who was intricately involved in
    Evans’s operations. The Government’s attitude towards her would be obvious.
    42
    Case: 17-20158   Document: 00514544493     Page: 43   Date Filed: 07/06/2018
    No. 17-20158
    For the foregoing reasons, we AFFIRM all of Evans’s convictions and his
    sentence.
    43