United States v. Andrew E. Fisher ( 2022 )


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  • USCA11 Case: 21-11879     Date Filed: 09/13/2022   Page: 1 of 48
    [DO NOT PUBLISH]
    In the
    United States Court of Appeals
    For the Eleventh Circuit
    ____________________
    No. 21-11879
    ____________________
    UNITED STATES OF AMERICA,
    Plaintiff-Appellee,
    versus
    ANDREW E. FISHER,
    Defendant-Appellant.
    ____________________
    Appeal from the United States District Court
    for the Northern District of Florida
    D.C. Docket No. 3:19-cr-00076-MCR-1
    ____________________
    USCA11 Case: 21-11879         Date Filed: 09/13/2022     Page: 2 of 48
    2                       Opinion of the Court                  21-11879
    Before WILSON, BRANCH, and LAGOA, Circuit Judges.
    LAGOA, Circuit Judge:
    Andrew Fisher appeals his convictions for conspiracy to
    commit health care fraud, in violation of 
    18 U.S.C. §§ 1347
    , 1349;
    conspiracy to commit wire fraud, in violation of 
    18 U.S.C. §§ 1343
    ,
    1349; and conspiracy to commit money laundering in violation of
    
    18 U.S.C. §§ 1956
    (h), 1957. On appeal, Fisher argues that: (1) the
    evidence at trial was not legally sufficient to warrant his convic-
    tions, and (2) the district court’s failure to provide limiting instruc-
    tions to the jury on the alleged means of accomplishing the con-
    spiracy amounted to approving a constructive amendment of the
    indictment. After careful review, and with the benefit of oral argu-
    ment, we affirm.
    I.     BACKGROUND
    In July 2019, a federal grand jury indicted Andrew Fisher for
    his role in a scheme to defraud TRICARE, a federal health insur-
    ance program. Count One of the indictment charged Fisher with
    conspiracy to commit health care and wire fraud, in violation of 
    18 U.S.C. §§ 1343
    , 1347, and 1349. Count Two charged Fisher with
    conspiracy to commit money laundering, in violation of 
    18 U.S.C. §§ 1956
    (h) and 1957.
    Both charges concerned Fisher’s conduct that occurred be-
    tween October 2014 and December 2015 as the head of a pharmacy
    he opened and ran in Florida. The indictment mainly alleged that
    Fisher conspired to seek reimbursements from TRICARE for
    USCA11 Case: 21-11879            Date Filed: 09/13/2022        Page: 3 of 48
    21-11879                  Opinion of the Court                               3
    fraudulent prescriptions. According to the indictment, Fisher
    knew there was no legitimate doctor-patient relationship between
    the prescriber of the fraudulent prescriptions and the patient, yet
    Fisher agreed to have his pharmacy fill the prescriptions, ship the
    medications, and submit claims to TRICARE. Fisher would then
    pay his co-conspirator a commission of approximately fifty percent
    of any reimbursement received for a prescription submitted to
    Fisher by his co-conspirator or his co-conspirator’s employees. The
    indictment also alleged that Fisher sought reimbursements for pre-
    scriptions, while not seeking to enforce the co-pay requirement
    that was part of the TRICARE contract, and that Fisher directed his
    employees to use needlessly expensive ingredients in compound
    medications to maximize the reimbursements Fisher’s pharmacy
    could bill to TRICARE.
    The parties agree that Fisher owned and operated a phar-
    macy that was filling fraudulent prescriptions and seeking reim-
    bursement from a federal health insurance program called
    TRICARE, but Fisher claims he did not know the prescriptions
    were fraudulent. The government argues that Fisher was a know-
    ing and willing participant in the conspiracy to defraud TRICARE.
    The case proceeded to a jury trial and the trial record reflects
    the following.1
    1We “review de novo the sufficiency of the evidence to support a conviction,
    viewing the evidence in the light most favorable to the verdict and drawing all
    reasonable inferences and credibility choices in the verdict’s favor.” United
    USCA11 Case: 21-11879           Date Filed: 09/13/2022        Page: 4 of 48
    4                         Opinion of the Court                     21-11879
    A. General Background
    TRICARE is a federal medical benefits program that pro-
    vides health insurance to active duty and retired military service
    members and their families, including prescription drug benefits.
    TRICARE contracts with Express Scripts, Inc., to administer its pre-
    scription drug benefits in accordance with TRICARE rules and reg-
    ulations.
    In its role as TRICARE’s pharmacy benefits manager, Ex-
    press Scripts creates and manages the network of pharmacies eligi-
    ble to fill TRICARE prescriptions by contracting with those phar-
    macies on behalf of TRICARE. These pharmacies are called “net-
    work pharmacies.” TRICARE beneficiaries who fill prescriptions
    at network pharmacies are responsible only for a co-pay amount,
    instead of the total cost of the drug. Express Scripts’s network
    agreements state that a network pharmacy’s failing to collect re-
    quired co-pays may result in “immediate termination” from the
    network.
    Once a prescription is filled, the pharmacy submits a claim
    to Express Scripts for reimbursement. Express Scripts, on behalf of
    TRICARE, reimburses the pharmacy for covered drugs, at rates es-
    tablished by TRICARE. Express Scripts reimburses network phar-
    macies by electronic transfer or check through a central payment
    States v. Grow, 
    977 F.3d 1310
    , 1320 (11th Cir. 2020) (quoting United States v.
    Deason, 
    965 F.3d 1252
    , 1262 (11th Cir. 2020)).
    USCA11 Case: 21-11879       Date Filed: 09/13/2022     Page: 5 of 48
    21-11879               Opinion of the Court                        5
    processor—in this case, the American Pharmacy Cooperative,
    Inc.—which processes and later transfers the funds to the phar-
    macy. TRICARE rules require that prescriptions must be made un-
    der a licensed health care practitioner’s determination that the pre-
    scription is medically necessary for the beneficiary. In other words,
    if TRICARE or Express Scripts knew that a prescription was not
    written with a licensed practitioner’s determination that the pre-
    scription was medically necessary, they would deny the claim.
    The prescriptions at the center of this case were for “com-
    pound medications.” Unlike most prescription drugs, which are
    premade for the pharmacy to dispense, compound medications are
    prepared by a pharmacy by combining different ingredients specif-
    ically prescribed by a physician for an individual patient. Thus,
    they are reimbursed based on each individual ingredient in the
    compound. Examples of compound medications include scar
    creams, pain creams, and combinations of vitamins.
    During the relevant time, TRICARE’s prescription drug
    benefits included payment for certain individual ingredients of
    compound medications, some of which were reimbursed at ex-
    tremely high rates. In May 2015, TRICARE severely cut back cov-
    erage on compound medications, making compounding much less
    lucrative.
    B. The Underlying Conspiracy
    The conspiracy Fisher joined was in motion before Fisher
    got involved. And the underlying conspiracy is not in dispute. It
    USCA11 Case: 21-11879           Date Filed: 09/13/2022       Page: 6 of 48
    6                         Opinion of the Court                    21-11879
    started in 2013 when Scott Burton established a scheme with Brad
    Hodgson that involved submitting fraudulent prescriptions for
    TRICARE beneficiaries and seeking high reimbursement rates.
    Burton owned a company called Simply Surgical, which em-
    ployed many sales representatives working for commissions based
    on insurance reimbursements from compound medications.
    Hodgson worked as an assistant to Dr. Jeff Traub, an orthopedic
    surgeon with three offices in the Atlanta area. 2 Burton asked Hodg-
    son to write prescriptions for compound medications for Burton’s
    friends and family. These friends and family were not patients of,
    and never saw, Dr. Traub, but Burton told Hodgson that they had
    conditions requiring pain or scar creams. Because Hodgson was
    not licensed to prescribe medication, he first sought and received
    Dr. Traub’s permission to write the prescriptions on Dr. Traub’s
    behalf. But as the volume of Burton’s prescriptions increased,
    Hodgson stopped asking Dr. Traub for permission to write the pre-
    scriptions and continued signing Dr. Traub’s name. At trial, Hodg-
    son testified that Dr. Traub knew that Hodgson was writing pre-
    scriptions for Burton, but Dr. Traub “wasn’t aware of how many,
    how often, or where they were actually being sent.”
    Once the scheme got going, the process went as follows:
    Burton and his sales representatives would recruit people—mostly
    TRICARE beneficiaries—to receive prescriptions for compound
    2Hodgson was an assistant to the physician, not a physician assistant, and at
    no time was he licensed to prescribe medication.
    USCA11 Case: 21-11879       Date Filed: 09/13/2022     Page: 7 of 48
    21-11879               Opinion of the Court                        7
    medications with high reimbursement rates. Burton testified that
    he focused on compound prescriptions for TRICARE beneficiaries
    because “TRICARE was one of the highest paid, the highest reim-
    bursed” for compound prescriptions. Burton would email new
    “patient” information to Hodgson and another employee in Dr.
    Traub’s office, Marie Smith. This information included the per-
    son’s driver’s license and insurance cards and what prescription
    Hodgson should write. Smith would transfer the fake patient’s in-
    formation to Dr. Traub’s patient database to make it look like a real
    patient seen by Dr. Traub. Hodgson would then write the prescrip-
    tion, forge Dr. Traub’s signature, and send it off to the pharmacy.
    The pharmacy in turn would fill the prescription and seek reim-
    bursement from the insurance company.
    Once the pharmacy was reimbursed, the pharmacy would
    pay Burton his commission, which was fifty percent of the reim-
    bursement. Burton would then pay Hodgson $25 for every pre-
    scription that was reimbursed by the insurance company. In total,
    Hodgson made between $8,500 and $10,000 from the scheme. Bur-
    ton paid Smith $25 per hour for her efforts, as well as kickbacks for
    recruiting her husband to receive these compound medications
    and receiving the medications herself.
    As a result of this scheme, Burton pleaded guilty to conspir-
    acy to commit the crimes of health care fraud, wire fraud, and
    money laundering and the substantive crime of money laundering.
    Hodgson pleaded guilty to conspiracy to commit health care fraud,
    conspiracy to commit wire fraud, and the crimes of receiving
    USCA11 Case: 21-11879           Date Filed: 09/13/2022       Page: 8 of 48
    8                         Opinion of the Court                    21-11879
    health care kickbacks and identity theft. Other co-conspirators
    pleaded guilty for their participation, including Marie Smith.
    Burton, Hodgson, and Smith at first processed the fraudu-
    lent compound prescriptions through a TRICARE network phar-
    macy called Curant Heath. But Curant Health was not “in” on the
    scheme, and in August 2014, the pharmacy began asking questions
    about who was writing the prescriptions from Dr. Traub’s office
    and whether the prescriptions were for actual patients of
    Dr. Traub. Around August 2014, Burton testified, Curant Health
    refused to accept any more prescriptions from Dr. Traub. 3
    Burton was on the hunt for another TRICARE network
    pharmacy to sell compound medications with, when one of his for-
    mer sales representatives recommended Burton speak with An-
    drew Fisher.
    C. Fisher Opens Physician Specialty Pharmacy
    In September 2014, Fisher opened a pharmacy in Pensacola,
    Florida, called Physician Specialty Pharmacy. 4 Fisher was not
    3Burton testified that by August 2014, Curant Health would no longer accept
    prescriptions from Dr. Traub. Hodgson testified that Curant Health never
    refused to accept Dr. Traub prescriptions, but that he and Burton made the
    decision to transition to another pharmacy. Either way, it is undisputed that
    Curant Health had many questions about the prescriptions from Dr. Traub,
    and Burton wanted to work with a new pharmacy.
    4 Fisher was at least the majority owner of Physician Specialty Pharmacy
    through a corporate entity called Hydra Medical Ventures, which was owned
    USCA11 Case: 21-11879        Date Filed: 09/13/2022      Page: 9 of 48
    21-11879                Opinion of the Court                         9
    himself a pharmacist, but he held the title of President and was in
    charge of the pharmacy.
    To get the business off the ground, Fisher and his operations
    manager Cary McKnight procured a building, obtained a pharmacy
    license, and started contracting with insurance companies. Physi-
    cian Specialty Pharmacy hired pharmacists to develop and fill pre-
    scriptions, pharmacy technicians to assist the pharmacists, and pa-
    tient care specialists to gather and confirm patient demographic
    and insurance information. Two of the pharmacy’s key employees
    were Glenn Hanson as pharmacist-in-charge, and Vicki Cowart,
    who eventually became the sales representative liaison between
    Physician Specialty Pharmacy and its contract sales representatives.
    Physician Specialty Pharmacy specialized in compound
    medications. When Fisher opened Physician Specialty Pharmacy,
    TRICARE was the last reliable insurance company paying high re-
    imbursement rates for compound medications. Physician Spe-
    cialty Pharmacy obtained contracts to fill prescriptions for the ben-
    eficiaries of several insurance companies, but not TRICARE. To
    access TRICARE’s high reimbursement rates, Physician Specialty
    by MedPro Wealth Builders. In turn, MedPro Wealth Builders was owned by
    Fisher and his wife.
    USCA11 Case: 21-11879           Date Filed: 09/13/2022        Page: 10 of 48
    10                        Opinion of the Court                      21-11879
    Pharmacy entered into a “central fill agreement” with a TRICARE-
    network pharmacy in Pace, Florida, called Burklow Pharmacy. 5
    The business relationship between Physician Specialty Phar-
    macy and Burklow Pharmacy worked as follows: Physician Spe-
    cialty Pharmacy used Burklow Pharmacy’s billing system and con-
    tracts to bill for prescriptions that Physician Specialty Pharmacy re-
    ceived, filled, and shipped, and in exchange, Burklow Pharmacy
    would retain fifteen percent of the insurance reimbursements. At
    trial, the government asked Physician Specialty Pharmacy’s vice
    president of pharmacy operations whether it was normal for a cen-
    tral fill pharmacy to receive, fill, and ship prescriptions and use the
    originating pharmacy to bill for the prescriptions. The witness re-
    sponded, “That would not be a normal central fill agreement, no.”6
    Fisher had a similar arrangement with Jay Pharmacy in Santa Rosa
    County, Florida.
    D. Fisher’s Pharmacy Begins Filling Burton’s Fraudulent Pre-
    scriptions
    5 Central fill agreements allow nonnetwork pharmacies to contract with net-
    work pharmacies to fill prescriptions and bill through the network pharmacy
    to be eligible for reimbursement.
    6 During  his testimony, the witness explained how central fill agreements gen-
    erally work: “A central fill agreement would be Pharmacy A received the pre-
    scriptions, does the billing, and they send the prescription to Pharmacy B to
    actually fill it and send it out to the patient.”
    USCA11 Case: 21-11879      Date Filed: 09/13/2022     Page: 11 of 48
    21-11879               Opinion of the Court                      11
    When Burton and Fisher first made contact in the Fall of
    2014, their two businesses were operating separately. As noted, the
    Burton-Hodgson conspiracy was in full swing, and Burton was
    looking for a new pharmacy to fill the forged Dr. Traub prescrip-
    tions. Physician Specialty Pharmacy was up and running and was
    filling TRICARE prescriptions for compound medications through
    its central fill agreement with Burklow Pharmacy.
    By October 2014, the two men had spoken on the phone,
    played a round of golf, and come to a business arrangement: Bur-
    ton agreed to market Physician Specialty Pharmacy’s formulas for
    a fifty percent commission from the insurance reimbursements re-
    ceived on every prescription that Burton and his sales representa-
    tives forwarded to Physician Specialty Pharmacy. Burton would
    receive payments through his company, Simply Surgical, and
    would pay his representatives from his cut.
    Importantly, Burton also testified that in the initial phone
    call with Fisher, Burton told Fisher about his troubles with Curant
    Health and that he was looking for a pharmacy that would accept
    prescriptions from Dr. Traub. Burton described the conversation
    like this:
    So I told him—he asked me why we weren’t using the
    other pharmacy, [Curant Health,] and I said, we had
    a doctor, Dr. Traub, who was prescribing these pain
    and scar creams to patients that were friends of mine
    or my representatives or relatives that needed these
    pain and scar creams that were out of state; and that
    USCA11 Case: 21-11879       Date Filed: 09/13/2022     Page: 12 of 48
    12                     Opinion of the Court                 21-11879
    Dr. Traub didn’t actually see the patients. And I said,
    Dr. Traub was okay with this, because, as Dr. Traub
    said, this isn’t OxyContin; this is a pain – topical pain
    and scar cream, it’s not a big deal, I have been pre-
    scribing to friends and family for years.
    So I told Andrew Fisher that; and I said, look, is this
    going to be a problem at your pharmacy? He said, as
    long as it’s not a problem with the surgeon, I have no
    problem with it.
    At trial, Burton was asked whether there were other times
    he discussed with Fisher “the fact that these prescriptions didn’t
    have a real doctor/patient behind them”; Burton answered: “Many
    times.” Burton explained that because many of the patients Burton
    recruited were from out-of-state—and often in states that Physician
    Specialty Pharmacy was not licensed to dispense medications—
    they “would have to discuss, well, this is a patient from Dr. Traub
    who he didn’t actually see,” and the prescriptions would have to be
    shipped to an address in Georgia instead of the state in which the
    patient resided. Evidence at trial included an email sent by Fisher
    to Burton asking Burton to provide a Georgia address for out-of-
    state prescriptions of Dr. Traub. Burton gave his home address for
    shipping some prescriptions and testified that another sales repre-
    sentative also provided an Atlanta address for shipping prescrip-
    tions for out-of-state patients.
    Once Burton and Fisher came to an agreement, the Burton-
    Hodgson scheme continued pretty much as it had before, except
    Burton directed Hodgson to send all of Dr. Traub’s fraudulent
    USCA11 Case: 21-11879      Date Filed: 09/13/2022     Page: 13 of 48
    21-11879               Opinion of the Court                      13
    prescriptions directly to Physician Specialty Pharmacy, i.e., not to
    the TRICARE network pharmacies, Burklow Pharmacy or Jay
    Pharmacy. Burton and his sales representatives recruited
    TRICARE beneficiaries to accept compound medications without
    seeing Dr. Traub and sent the recruited patient information to
    Hodgson, who would forge the prescription and then fax the pre-
    scription from Dr. Traub’s office to Physician Specialty Pharmacy.
    Under Burton and Fisher’s arrangement, Burton and his
    sales representatives distributed Physician Specialty Pharmacy’s Rx
    pads—listing the pharmacy’s products and formulas—to physi-
    cians. Burton and his sales representatives also directly recruited
    their friends and family members who were TRICARE beneficiar-
    ies to provide their demographic and TRICARE information and
    accept the compound medications prescribed by Dr. Traub, with-
    out seeing the doctor. The government provided examples at trial
    of individuals who were friends or family members of Burton or
    his sales representatives who provided their TRICARE information
    for this purpose. As previously noted, Hodgson would send the
    forged prescriptions directly to Physician Specialty Pharmacy to
    fill. Despite the connection between Dr. Traub’s office and Physi-
    cian Specialty Pharmacy, there was no evidence Fisher knew that
    Hodgson was forging Dr. Traub’s signature; Hodgson testified that
    he never met Fisher or communicated with him in any way.
    Each of Burton’s sales representatives had a fax number
    linked to them, so that Physician Specialty Pharmacy would know
    which sales representative generated the prescription. Then,
    USCA11 Case: 21-11879      Date Filed: 09/13/2022    Page: 14 of 48
    14                    Opinion of the Court                21-11879
    Physician Specialty Pharmacy’s patient care specialists would con-
    firm the information. Once confirmed, they would submit the
    claim to the insurance company and forward the prescription to lab
    for filling. And once filled, the pharmacy shipped to the prescrip-
    tion to the patient.
    E. Fisher’s Pharmacy Begins Engaging in “Gray Area” Prac-
    tices
    Fisher’s employees at Physician Specialty Pharmacy did not
    know that some of Dr. Traub’s prescriptions were not based on a
    legitimate doctor-patient relationship. Physician Specialty Phar-
    macy had multiple patient care specialists who were responsible for
    confirming whether patient information was correct. But Fisher’s
    sales representative liaison Vicki Cowart became suspicious that
    something was awry in August 2015 when she received a troubling
    call from one of Burton’s sales representatives, Doran Fortune. She
    sent Fisher an email describing the call:
    I received a call from Doran Fortune, a Simply Surgi-
    cal rep. . . . Today he sounded worried and con-
    cerned. Doran said he has received a disturbing com-
    munication from our TRICARE patient, Mark T.
    Searles. Doran had personally suggested to the pa-
    tient that he visit Dr. Traub while in Atlanta. We re-
    ceived a script for this patient from Dr. Traub and
    filled four items between 4/29 and 4/30/15, each as a
    90-day supply and the patient had no co-pay. Accord-
    ing to Doran, the patient never received the meds. In
    fact, the patient lives in Woodbridge, Virginia . . . .
    USCA11 Case: 21-11879      Date Filed: 09/13/2022   Page: 15 of 48
    21-11879              Opinion of the Court                     15
    [T]he patient received an EOB from TRICARE show-
    ing we billed $118,000 and TRICARE paid $95,000.
    Patient assumes that $23,000 is owed. Patient is com-
    pletely astounded at these amounts and feels he
    somehow is involved in our fraudulent billing prac-
    tices through Jay Pharmacy. I confirmed through Jay
    PK that TRICARE should be paying us $95,599.76 for
    90-day supplies of the four medications Dr. Traub
    submitted on his prescription. . . .
    I reminded Doran that we absolutely do not partici-
    pate in anything fraudulent. I also checked the deliv-
    ery information from UPS, and two packages of meds
    were delivered to and signed for at the condominium
    address in Atlanta which we were provided by Dr.
    Traub’s office as being the patient’s address.
    In the same email, Cowart reported to Fisher that Doran told her
    about “10 of his close friends who [Searles] recommended to Dr.
    Traub on Scott Burton’s recommendation” and that “[i]t sounds
    like they all filled out a questionnaire provided by Dr. Traub and
    possibly none of them were actually seen.”
    In response, Fisher thanked Cowart, said he would call
    Doran, and asked Cowart why the prescriptions were sent to Geor-
    gia. Here is the rest of the email exchange:
    Cowart: “The address we shipped to was provided by
    Dr. Traub.”
    Fisher: “But what address did we verify with the pa-
    tient, the Georgia address or the Virginia address?”
    USCA11 Case: 21-11879        Date Filed: 09/13/2022     Page: 16 of 48
    16                      Opinion of the Court                 21-11879
    Cowart: “We verified the Georgia address according
    to the notes. I am checking the other patients I know
    to be those of Doran Fortune, and I have found a sec-
    ond one with the same Atlanta address. Heather ran
    an ad hoc report, and it appears four out of Doran’s
    14 patients had meds shipped to the same . . . address
    in Atlanta. I smell a fish. Vicki.”
    Fisher: “I know in the past we have sent medications
    for Dr. Traub’s patients to an address of someone in
    his office so the patient can pick them up. We’ll have
    to figure out what is going on in this particular situa-
    tion. Let’s not jump to conclusions until we have a
    chance to gather more info. Thank you.”
    There is no evidence that Fisher took any action.
    Earlier in the trial, Burton testified that he told Fisher that
    Fortune had recruited many patients at a bachelor party. An email
    listed the names of attendees, and Mark Searles was on the list. Ac-
    cording to Burton, Fisher’s only concern with that list of patients
    was that they were from out-of-state, and Fisher told Burton to use
    an Atlanta address for them.
    While unaware of the Burton-Hodgson scheme, several
    Physician Specialty Pharmacy employees testified to “gray area”
    pharmacy practices at Physician Specialty Pharmacy, with “gray
    area” meaning that the practices were not per se illegal. But the
    employees believed those practices may have been part of a bigger
    scheme. In fact, Cary McKnight testified that during a conversation
    about Physician Specialty Pharmacy’s sales representatives, Fisher
    USCA11 Case: 21-11879      Date Filed: 09/13/2022   Page: 17 of 48
    21-11879              Opinion of the Court                     17
    said, “that he knew that the pharmacy is supposed to be black and
    white but that he liked to operate in the gray area.”
    One of these “gray area” practices was billing TRICARE for
    expensive ingredients. Claims for compound medications using
    different ingredients could vary widely. For example, if a com-
    pound cream used Lipoderm as the base, Physician Specialty Phar-
    macy could be reimbursed $580.47, while a similar base ingredient
    called Stera Base could be reimbursed for $3,368.16. Of course,
    making money is not illegal, but the government presented evi-
    dence that Fisher was singularly focused on maximizing profitabil-
    ity. For example, McKnight testified about discussions with Fisher
    about how to bill the most from insurance and how ingredients of
    some formulas changed over time to increase profitability. And,
    according to Burton, Fisher had a method for creating formulas
    that would pay the most from each insurance company. Physician
    Specialty Pharmacy would send out “trial reimbursement[s]” using
    different ingredients to see what would “get the maximum amount
    of reimbursement for each insurance company.” Burton further
    testified that the draw of using Physician Specialty Pharmacy was
    that Fisher “had a system in place” to “get maximum reimburse-
    ments from each insurance company.”
    At trial, the government asked McKnight—former pharma-
    cist-in-charge at Physician Specialty Pharmacy—about specific
    times a Physician Specialty Pharmacy formula changed to increase
    profitability. McKnight responded that Fluticasone “always comes
    to mind” because it was “a very expensive ingredient” used in scar
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 18 of 48
    18                     Opinion of the Court                21-11879
    gels that “elevated the price” that Physician Specialty Pharmacy
    could bill the insurance companies. He said that the pharmacy he
    worked at before Physician Specialty Pharmacy used .1 percent of
    Fluticasone in their scar gel, but Physician Specialty Pharmacy
    “changed to a full 1 percent Fluticasone, which was 10 times more
    than what we were using.” McKnight added that “[t]he pharmacist
    at the time questioned it because, according to them, it wasn’t—
    the efficacy of increasing the Fluticasone was not beneficial. But
    that is, again, between them and the doctor.” McKnight also testi-
    fied that, although the pharmacists had input into the development
    of the compounded prescription formulas, Fisher had the final say
    in approving them.
    Glen Hanson, the former pharmacist-in-charge at Physician
    Specialty Pharmacy, also testified that a scar cream formula was
    changed “because of the high reimbursement amount.” Hanson
    testified that Fisher, another pharmacist, and a sales representative
    went to Louisiana to find a different base that “would gross more
    money.” As a result of the trip to Louisiana, Physician Specialty
    Pharmacy switched from a cream base called Lipoderm to a more
    expensive base called Stera Base. Though more expensive, Hanson
    testified that Stera Base was “a poor quality product” because it was
    runny and did not hold the ingredients together as well as the
    cheaper base.
    Hanson testified that tension developed between him and
    Fisher over the formulas because Hanson was concerned about the
    quality of the product and Fisher was concerned with using
    USCA11 Case: 21-11879       Date Filed: 09/13/2022     Page: 19 of 48
    21-11879               Opinion of the Court                        19
    ingredients to increase profits. For example, when Fisher sus-
    pected that the pharmacists were not using Stera Base, he emailed
    Hanson, stating:
    One of the claims was a pain cream for 480 grams that
    reimbursed around 4,000. If we used and billed Stera
    Base, it should be twice that. Please check on these
    patients and make sure we used and billed Stera Base.
    If we did not bill Stera Base, please reverse and bill
    them utilizing a formula with Stera Base.
    Hanson also testified to a disagreement over a decision by Fisher
    not to reverse an insurance claim after a customer had returned the
    product, which caused Hanson to resign.
    In a voluntary interview with Vanessa Carmona—an agent
    of the Florida Department of Law Enforcement and a task force
    officer with the Federal Bureau of Investigation—Fisher told Agent
    Carmona that when he started Physician Specialty Pharmacy, he
    knew TRICARE was the “last reliable insurance company that paid
    for compounds.” Agent Carmona testified that Fisher told her
    “whatever the maximum reimbursable amount was that he could
    get from the insurance company, that that’s what he was going to
    charge.” For example, “if it cost him $500 to make a prescription,
    but TRICARE was willing to pay $6,000, then he was going to bill
    that maximum amount for that prescription.” Agent Carmona tes-
    tified that Fisher “agreed that it was inflated, but he also said that
    . . . if they were willing to pay that much—‘they’ being like
    TRICARE, the insurance companies—then they were going to bill
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 20 of 48
    20                     Opinion of the Court                21-11879
    the maximum that they were allowed to.” Agent Carmona testi-
    fied that Fisher said he “felt like he took advantage of” TRICARE’s
    high reimbursement rates, but “stated several times that he felt like
    everything he did was within the law, and that he had not de-
    frauded anybody.”
    The government also presented evidence that Fisher disre-
    garded the pharmacy’s duty to collect co-pays from the patients.
    Burton testified that “the co[-]pay part came up quite a bit” because
    “patients didn’t want to pay the co[-]pay.” Burton testified that
    “Fisher contacted [him] by phone” and told him “if you’re having
    any issues with patients not wanting to pay or if your reps have
    issues or anybody dealing with these patients are getting a call, let
    the patients know that by law we have to bill the patients one time”
    and that “[i]f they don’t pay their co[-]pay, we’re not going to send
    them to collections, so just let them know they can throw that bill
    away, they don’t need to pay it.”
    Cary McKnight also testified that Fisher was not concerned
    about co-pays and referenced an incident described in an email
    drafted by Fisher. A patient had balked at a $17 co-pay, and Fisher
    instructed McKnight to ship the medication and simply send an in-
    voice and write the co-pay off if the customer continued to balk.
    According to McKnight, Fisher’s philosophy was that: “if you got a
    $5,000 prescription, you’re not worried about a hundred dollar co-
    pay.” Burton testified that Fisher said something similar to him,
    i.e., that Fisher “didn’t want to let a $10,000 reimbursement go
    away because somebody didn’t want to pay a $17 co-pay.”
    USCA11 Case: 21-11879       Date Filed: 09/13/2022     Page: 21 of 48
    21-11879               Opinion of the Court                        21
    Vicki Cowart’s notes from work, which she read during her
    testimony at trial, indicated that she received similar instructions
    regarding co-pays, although she could not remember from whom.
    Cowart also referenced a procedure for “force fills,” which she de-
    scribed as filling prescriptions without getting the patient’s consent
    beforehand.
    F. The Scheme Unravels
    Eventually, Fisher started looking to purchase pharmacies to
    spread out Physician Specialty Pharmacy’s billing as not to draw
    attention from the insurance companies. He emailed Physician
    Specialty Pharmacy stakeholders, stating:
    [T]he main reasons we are looking into purchasing
    this pharmacy, in addition to it potentially being a
    good investment in and of itself is, one, so that we can
    expand our operations. The insurance companies ac-
    tively target pharmacies that bill over a certain
    amount per month, so having multiple pharmacies
    billing a lower amount each month is an ideal strat-
    egy for staying off their radar. The second reason is
    because right now we are paying the pharmacy that
    we bill through around 13 percent of our gross sales.
    So for December, we basically paid them $390,000 to
    let us bill through their contracts. While I do appreci-
    ate their willingness to work with us, that is com-
    pletely ridiculous, given that we do 99.74 percent of
    the work, and it is all of our business.
    And, in February 2015, Fisher acquired Jay Pharmacy.
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 22 of 48
    22                     Opinion of the Court                21-11879
    As it turns out, Fisher’s fears were well founded. Eventually,
    Burklow Pharmacy, Jay Pharmacy, and Physician Specialty Phar-
    macy came under scrutiny from TRICARE’s pharmacy benefits
    manager Express Scripts and the central payor, American Phar-
    macy Cooperative, because of extraordinarily high billings and a
    concern as to whether the doctor-patient relationships underlying
    the pharmacies’ claims were legitimate.
    In late 2014, an accountant from American Pharmacy Coop-
    erative noticed a huge surge in Burklow Pharmacy’s billing, rising
    from between $200,000 and $300,000 per month to $1 million.
    American Pharmacy Cooperative therefore withheld payments to
    Burklow Pharmacy from Express Scripts, and TRICARE suspended
    claim payments for all claims from Burklow Pharmacy.
    Then, in March 2015, Fisher received notice that TRICARE
    would be initiating new screening procedures for compounded
    medication claims as of May 1, 2015, making it harder to bill for
    compounded medications. Fisher referred to this date as “D-Day”
    and, before that date, Fisher pushed to “bill as much as possible”
    and then to “refill as many of those as possible as 90-day supplies”
    before May 1. To implement his plan, Fisher sent a letter asking
    his doctors to sign authorizations for 90-day refills. For Dr. Traub,
    Fisher sent the letter to Burton. Hodgson forged Dr. Traub’s sig-
    nature and Burton returned the 90-day authorization to Fisher alt-
    hough there is no evidence that Fisher was aware of the forgery.
    Because of Fisher’s “D-Day” plan, billings skyrocketed in
    April 2015. By May 2015, Jay Pharmacy went from billing “around
    USCA11 Case: 21-11879      Date Filed: 09/13/2022    Page: 23 of 48
    21-11879              Opinion of the Court                      23
    $1500 per month” to billing “several million.” This drew the atten-
    tion of American Pharmacy Cooperative, which placed a hold on
    Jay Pharmacy’s TRICARE reimbursement checks in May 2015.
    American Pharmacy Cooperative returned Jay Pharmacy’s entire
    payment to Express Scripts, and TRICARE later terminated its con-
    tract with Jay Pharmacy. Express Scripts withheld the payment
    while it performed an audit on Jay Pharmacy.
    Because Express Scripts was withholding payments, Fisher
    could not pay Burton or any other sales representatives for the
    commissions they were owed from those reimbursements. On
    June 23, 2015, Fisher emailed Burton and other “[Physician Spe-
    cialty Pharmacy] partners” explaining that American Pharmacy
    Cooperative was “still withholding our funds” while Express
    Scripts conducted an audit. The email included a letter attachment
    addressed to Jay Pharmacy informing the pharmacy that Express
    Scripts planned to audit the pharmacy.
    Express Scripts also began an audit on Burklow Pharmacy’s
    claims for compound medications to determine whether they were
    based on doctor-patient relationships. On October 23, 2015, Fisher
    received an email from a business associate forwarding an email
    originally sent to Steve Burklow with a letter attachment from the
    Office of the Assistant Secretary of Defense (the “DOD letter”).
    The DOD letter informed Burklow, as president of Burklow Phar-
    macy, that all “payment for present and future claims for services
    provided by you or your organization” would be suspended “due
    to you having dispensed compound drugs to TRICARE
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 24 of 48
    24                     Opinion of the Court                21-11879
    beneficiaries based upon prescriptions written by physicians who
    may not have established a physician/patient relationship with the
    TRICARE beneficiary.” The DOD letter stated that in the absence
    of a valid or appropriate doctor-patient relationship, a prescription
    is not valid, and therefore not reimbursable under TRICARE.
    On November 17, 2015, in response to the DOD letter,
    Burklow’s attorney sent out letter affidavits, asking Burklow and
    Fisher to have each doctor sign to attest that the prescriptions were
    based on legitimate doctor-patient relationships, in order to satisfy
    TRICARE.
    Fisher and Burklow discussed the audit and the letter affida-
    vits. Burklow testified that TRICARE “wanted affidavits from each
    doctor” to “establish the doctor/patient relationship” existed, and
    Burklow sent Fisher a letter to have his doctors sign. Burklow tes-
    tified that he told Fisher why he needed the letters and specifically
    told him that TRICARE was concerned about a lack of doctor-pa-
    tient relationships.
    Fisher sent the letter affidavit to Burton for Dr. Traub to
    sign, accompanied by an email explaining the letter affidavit. In
    that email, Fisher informed Burton that Burklow Pharmacy was
    being audited by TRICARE and needed to verify the doctor-patient
    relationship and assured Burton that this was nothing to be
    alarmed about. The letter affidavit attached to the email read:
    My name is Dr. Jeff Traub. I am a licensed and prac-
    ticing physician in the state of Georgia. As a treat-
    ment for my patients, I have written compounding
    USCA11 Case: 21-11879          Date Filed: 09/13/2022        Page: 25 of 48
    21-11879                  Opinion of the Court                            25
    prescriptions. In all cases, I personally met with each
    patient for whom I wrote a prescription. I evaluated
    every patient for whom I wrote a compounding pre-
    scription based on my professional expertise. It is ab-
    solutely and equally true that I only wrote and write
    prescriptions for patients with whom I had properly
    established a physician-patient relationship. More
    specifically, it is my understanding that some com-
    pounding prescriptions for my patients covered by
    TRICARE were submitted to TRICARE or its pro-
    cessing agents by Burklow Pharmacy. Any prescrip-
    tion written by me and submitted by Burklow Phar-
    macy was done in all cases for patients with whom I
    had established a proper physician-patient relation-
    ship.
    (Emphasis added).
    Burton testified that Fisher called Burton before sending the
    letter affidavit for Dr. Traub to sign, and Fisher explained that if
    Burton wanted to receive the commissions that were being with-
    held, he would have to get the letter signed. 7 Burton testified that
    he told Fisher that he would send the letters, but that Dr. Traub
    7 Burton testified that it was common for Fisher to call him before or after
    Fisher emailed. Burton said Fisher would call “[t]o clear up things before he
    sent the email over” because “[u]sually the email, you know, it was going to
    be a little bit different than what we talked about” because Fisher would not
    want to put certain things in writing.
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 26 of 48
    26                     Opinion of the Court                21-11879
    might not sign the letter because he had not personally seen the
    patients.
    Burton sent the letter affidavit to Hodgson, who signed and
    returned it to Burton. At trial, Hodgson testified that the statement
    attesting that Dr. Traub had authorized all prescriptions based on
    a proper doctor-patient relationship was not true. Nonetheless,
    Burton sent the signed letter affidavit back to Fisher with an email
    stating, “Hope this helps. All my docs prescribed these meds to
    their patients who legitimately needed them. They have files on
    all their patients. So this info should help us get the money we are
    owed.” Burton testified that the email was a lie, and that Fisher
    knew it was not true. However, even Burton said that he thought
    Dr. Traub signed the letter.
    In December 2015, Fisher voluntarily sat for an interview
    with Agent Carmona. During the interview, Fisher explained that
    he opened Physician Specialty Pharmacy because he knew there
    was a lot of money to be made in the compounding pharmaceutical
    business. He acknowledged that the insurance reimbursement
    rates had created an inflated system, and, as previously noted, he
    admitted that he took advantage of that system.
    In that interview, Fisher said that Physician Specialty Phar-
    macy entered a central fill agreement with Burklow Pharmacy be-
    cause Burklow Pharmacy was understaffed and needed help. Ac-
    cording to Fisher, Burklow Pharmacy would forward prescriptions
    to Physician Specialty Pharmacy by fax, and Burklow Pharmacy
    was responsible for collecting the co-pays, although Physician
    USCA11 Case: 21-11879       Date Filed: 09/13/2022     Page: 27 of 48
    21-11879               Opinion of the Court                        27
    Specialty Pharmacy would invoice the co-pays. Fisher told Agent
    Carmona that Physician Specialty Pharmacy stopped dealing with
    Burklow Pharmacy in April or May 2015 because Burklow Phar-
    macy lost its contract with TRICARE. Fisher claimed he did not
    know why Burklow Pharmacy lost the contract, even though he
    received the DOD letter and email almost two months before the
    interview.
    According to Agent Carmona, Fisher also contradicted him-
    self during the interview. For example, at one point Fisher told
    Agent Carmona that Physician Specialty Pharmacy’s sales repre-
    sentatives did not recruit patients, but in the same interview he also
    told Agent Carmona that Physician Specialty Pharmacy used sales
    representatives to market to TRICARE patients—i.e., “the last re-
    liable insurance company that paid for [Fisher’s] compounds.”
    In February 2016, law enforcement executed a federal search
    warrant at Physician Specialty Pharmacy. Law enforcement also
    obtained Physician Specialty Pharmacy’s emails and bank records,
    as well as records from Dr. Traub’s office. At trial, Suzanne
    Reyenga, a forensic accountant with the FBI, testified concerning
    a financial analysis of these records. Reyenga testified that, from
    October 2014 to August 2015, American Pharmacy Cooperative
    paid $19.5 million to Burklow Pharmacy. Burklow Pharmacy
    transferred $16.3 million, of that $19.5 million, to Physician Spe-
    cialty Pharmacy, and Physician Specialty Pharmacy paid approxi-
    mately $8.3 million in commissions to various sales representa-
    tives. Of the total commissions paid, Physician Specialty Pharmacy
    USCA11 Case: 21-11879      Date Filed: 09/13/2022    Page: 28 of 48
    28                    Opinion of the Court                21-11879
    transferred approximately $2 million to Simply Surgical—Burton’s
    company. Reyenga further testified that, on several occasions,
    Physician Specialty Pharmacy transferred more than $10,000 to
    Burton’s account, specifically for prescriptions from Dr. Traub.
    Special Agent Paul Tarnuzzer of the Department of De-
    fense, Criminal Investigative Service, testified about Dr. Traub’s
    patient files and pharmacy records. Agent Tarnuzzer identified
    several TRICARE beneficiaries who were not actual patients of Dr.
    Traub, but whose demographic information had been submitted
    by Burton and his sales representatives for a prescription and for
    TRICARE reimbursement. In fact, Tarnuzzer identified only
    twelve prescriptions for actual patients of Dr. Traub. Agent
    Tarnuzzer testified that the total amount TRICARE paid to
    Burklow Pharmacy alone, on claims for prescriptions written by
    Dr. Traub, was approximately $3.3 million. In total, between Oc-
    tober 20, 2014 and June 30, 2015, TRICARE was billed approxi-
    mately $6.2 million, and paid approximately $4.8 million, on pre-
    scriptions submitted in Dr. Traub’s name by Burton and his repre-
    sentatives.
    G. Fisher’s Defense at Trial
    In his defense, Fisher presented the testimony of three Phy-
    sician Specialty Pharmacy employees to show the normal business
    operations at Physician Specialty Pharmacy: pharmacist Thomas
    Wiley; patient care specialist April Ryan; and marketing coordina-
    tor Kylie Hunt.
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 29 of 48
    21-11879               Opinion of the Court                       29
    Fisher originally hired Thomas Wiley in December 2014 as
    a “knowledge pharmacist” to help educate the sales representatives
    on Physician Specialty Pharmacy’s products and formulas. Wiley
    also filled in as a pharmacist sometimes, and in May 2015, Fisher
    promoted him to vice president of pharmacy operations. Wiley
    testified that he, and all of the other pharmacists at Physician Spe-
    cialty Pharmacy, had input into developing the Rx pads: “The phar-
    macists always would get together and approve any new prescrip-
    tion pad that was presented to us . . . to review it, to make sure
    there are no errors, there are no therapy mistakes, no directions
    that are wrong, before we send it out.” He testified that a pharma-
    cist at Physician Specialty Pharmacy signed off on every prescrip-
    tion, meaning that the pharmacist was “approving that prescription
    as being safe and effective for the patient’s condition.” Wiley also
    testified that Fisher never pressured him or any pharmacist to “use
    a formula or ingredient that [the] pharmacist[] was not comfortable
    with.”
    Patient care representative April Ryan began working for
    Physician Specialty Pharmacy in December 2014. She testified that
    Physician Specialty Pharmacy confirmed prescriptions, verified pa-
    tient demographic information, and “if there was something that
    looked to be untruthful or that it was deceitful in any way, then we
    would not proceed with that prescription.” She stated that the
    pharmacy records showed that more than twenty percent of the
    Dr. Traub prescriptions were refused (188 were refused out of 925
    USCA11 Case: 21-11879        Date Filed: 09/13/2022     Page: 30 of 48
    30                      Opinion of the Court                 21-11879
    prescriptions), with notations such as insurance denied, patient de-
    nied, patient could not be reached, or unlicensed state.
    Physician Specialty Pharmacy marketing coordinator Kylie
    Hunt started in April 2015. In an attempt to rebut the govern-
    ment’s argument that Fisher did not collect TRICARE co-pays
    from patients, Hunt testified that according to a 2015 accounts re-
    ceivable report, Jay Pharmacy, which was then owned by Fisher,
    collected co-pays from TRICARE beneficiaries. But, as the govern-
    ment pointed out on cross-examination, the earliest co-pay related
    entry on the report was July 30, 2015.
    In his closing argument, Fisher argued that the government
    failed to prove that he knowingly and willfully joined a health care
    fraud conspiracy, wire fraud conspiracy, or money laundering con-
    spiracy with Burton. Fisher maintained that Burton’s testimony
    was not credible, that he was unaware of Hodgson’s forgery, that
    the “gray area” pharmacy practices were not unlawful, and that his
    voluntary interview with investigators showed his lack of willful
    intent to join Burton’s conspiracy.
    H. Jury Instructions, Deliberations, and Verdict
    On the final day of trial, the district court and counsel re-
    viewed the proposed jury instructions and the verdict form. The
    district court gave the initial portion of its instructions to the jury
    before the parties gave their closing arguments and gave the rest of
    its instructions after closing arguments. After the court provided
    the jury with all of its instructions, and before the jury retired to
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 31 of 48
    21-11879               Opinion of the Court                       31
    deliberate, the district court asked counsel if there was “any objec-
    tion to the instructions as delivered by the Court to the jury.” The
    government responded: “None from the government.” The court
    then specifically asked for Fisher’s two attorneys by name for their
    response. One of the attorneys, Mr. Feldman, responded: “No ob-
    jection, Your Honor.” In other words, the defense did not object
    either to constructive amendment of the indictment or inadequacy
    of the instructions.
    Following five days of trial, the jury retired to deliberate.
    During deliberations, the jury sent one communication to the
    Court, asking whether it is health care fraud to send a prescription
    to a third party in a licensed state with the understanding that the
    prescription will be forwarded to a patient in an unlicensed state.
    The district court answered, “No,” and stated that “those facts
    would not, in and of themselves constitute conspiracy to commit
    health care fraud,” and cautioned the jury that the court could not
    comment on the evidence.
    Following deliberations, the jury returned a verdict of
    “guilty” on both counts. Fisher was sentenced to 24 months’ im-
    prisonment and ordered to forfeit $4.8 million to TRICARE. Fisher
    timely appealed the jury verdict, the order of forfeiture, and the
    sentence, arguing the evidence produced at trial was insufficient to
    support his convictions and that his indictment was constructively
    amended in violation of his Fifth Amendment rights.
    II.    STANDARD OF REVIEW
    USCA11 Case: 21-11879          Date Filed: 09/13/2022   Page: 32 of 48
    32                     Opinion of the Court                 21-11879
    We review the sufficiency of the evidence to support a con-
    viction de novo, “viewing the evidence in the light most favorable
    to the verdict and drawing all reasonable inferences and credibility
    choices in the verdict’s favor.” United States v. Grow, 
    977 F.3d 1310
    , 1320 (11th Cir. 2020) (quoting United States v. Deason, 
    965 F.3d 1252
    , 1262 (11th Cir. 2020)). “We may not overturn the jury’s
    verdict ‘if any reasonable construction of the evidence would have
    allowed the jury to find the defendant guilty beyond a reasonable
    doubt.’” United States v. Estepa, 
    998 F.3d 898
    , 908 (11th Cir. 2021)
    (quoting United States v. Capers, 
    708 F.3d 1286
    , 1297 (11th Cir.
    2013)). “To support a conviction, ‘[t]he evidence need not be in-
    consistent with every reasonable hypothesis except guilt, and the
    jury is free to choose between or among the reasonable conclu-
    sions to be drawn from the evidence presented at trial.’” 
    Id.
     (quot-
    ing Capers, 708 F.3d at 1297).
    We generally review de novo “an alleged constructive
    amendment of the indictment.” United States v. Feldman, 
    931 F.3d 1245
    , 1253 (11th Cir. 2019). But when a defendant fails to object to
    an alleged constructive amendment in the case below, we review
    only for plain error. United States v. Holt, 
    777 F.3d 1234
    , 1261
    (11th Cir. 2015). And “[w]hen a party agrees with a court’s pro-
    posed instructions, the doctrine of invited error applies, meaning
    that review is waived even if plain error would result.” Grow, 977
    F.3d at 1330 (quoting United States v. Frank, 
    599 F.3d 1221
    , 1240
    (11th Cir. 2010)).
    III.      ANALYSIS
    USCA11 Case: 21-11879       Date Filed: 09/13/2022     Page: 33 of 48
    21-11879               Opinion of the Court                        33
    Fisher asks this court to overturn his convictions for two rea-
    sons. First, Fisher argues the evidence was insufficient to sustain
    his conspiracy convictions. Second, Fisher argues that the district
    court’s jury instructions amounted to a constructive amendment
    of the indictment. We address Fisher’s arguments in turn.
    A. Sufficiency of the Evidence
    Fisher was convicted and sentenced for conspiracy to com-
    mit health care fraud, in violation of 
    18 U.S.C. §§ 1347
    , 1349; con-
    spiracy to commit wire fraud, in violation of 
    18 U.S.C. §§ 1343
    ,
    1349; and conspiracy to commit money laundering in violation of
    
    18 U.S.C. §§ 1956
    (h), 1957. On appeal, Fisher contends that the
    government’s evidence was insufficient to sustain his conspiracy
    convictions because there was no evidence that he knew that
    Dr. Traub’s prescriptions were fraudulent.
    The crime of health care fraud is defined by 
    18 U.S.C. § 1347
    .
    Section 1347(a) makes it a crime to
    knowingly and willfully execute[], or attempt[] to ex-
    ecute, a scheme or artifice-- (1) to defraud any health
    care benefit program; or (2) to obtain, by means of
    false or fraudulent pretenses, representations, or
    promises, any of the money or property owned by, or
    under the custody or control of, any health care ben-
    efit program, in connection with the delivery of or
    payment for health care benefits, items or services.
    Under 
    18 U.S.C. § 1349
    , it a crime to “attempt[] or conspire[]
    to commit any offense under this chapter,” including health care
    USCA11 Case: 21-11879        Date Filed: 09/13/2022     Page: 34 of 48
    34                      Opinion of the Court                 21-11879
    fraud. “[T]o sustain a conviction for conspiracy to commit health
    care fraud in violation of 
    18 U.S.C. §§ 1347
     and 1349 . . . , the
    [g]overnment had to establish beyond a reasonable doubt that:
    (1) a conspiracy existed to commit health care fraud under
    
    18 U.S.C. § 1347
    ; (2) [Fisher] knew of the conspiracy; and
    (3) [Fisher] knowingly and voluntarily joined it.” United States v.
    Gonzalez, 
    834 F.3d 1206
    , 1214 (11th Cir. 2016). Specifically, the
    government had to establish that Fisher knew the claims he sub-
    mitted to TRICARE were fraudulent. 
    Id.
     (citing United States v.
    Medina, 
    485 F.3d 1291
    , 1297 (11th Cir. 2007)). As Fisher argues,
    “[t]he principal issue at trial was,” and the principal issue on appeal
    is, “whether Fisher knew what Burton was doing; that is, did Fisher
    know that the prescriptions were fraudulent.”
    “Because the crime of conspiracy is predominantly mental
    in composition, it is frequently necessary to resort to circumstantial
    evidence to prove its elements.” United States v. Abovyan, 
    988 F.3d 1288
    , 1302 (11th Cir. 2021) (quoting United States v. Toler, 
    144 F.3d 1423
    , 1426 (11th Cir. 1998)). Indeed, “[g]uilty knowledge can
    rarely be established by direct evidence, especially in respect to
    fraud crimes which, by their very nature, often yield little in the
    way of direct proof.” United States v. Clay, 
    832 F.3d 1259
    , 1309
    (11th Cir. 2016) (quoting United States v. Suba, 
    132 F.3d 662
    , 673
    (11th Cir. 1998)). A defendant can be found guilty of participating
    in a conspiracy “if the evidence demonstrates that he was aware of
    the conspiracy’s essential nature, even if he did not know all of its
    details, played only a minor role in the overall scheme, did not have
    USCA11 Case: 21-11879            Date Filed: 09/13/2022         Page: 35 of 48
    21-11879                   Opinion of the Court                               35
    direct contact with other alleged co-conspirators, or did not partic-
    ipate in every stage of the conspiracy.” Abovyan, 988 F.3d at 1302–
    03 (quoting United States v. Sosa, 
    777 F.3d 1279
    , 1290 (11th Cir.
    2015)); see also United States v. Reeves, 
    742 F.3d 487
    , 497–98 (11th
    Cir. 2014).
    Viewing the evidence in the light most favorable to the ver-
    dict, and based on both the direct and circumstantial evidence de-
    scribed below in this case involving a conspiracy to commit health
    care fraud, we hold that a reasonable jury could find beyond a rea-
    sonable doubt that: (1) Fisher knew of the conspiracy, and (2)
    Fisher knowingly and voluntarily joined the conspiracy by submit-
    ting claims to TRICARE that he knew were fraudulent. 8
    8 While   Fisher purportedly appeals all three of his conspiracy convictions, the
    arguments in his brief to this Court only focus on his claim that there was
    insufficient evidence to support his conviction for conspiracy to commit
    health care fraud. Turning to these other conspiracy convictions, the elements
    of conspiracy to commit wire fraud, in violation of 
    18 U.S.C. § 1349
    , are: (1)
    that a conspiracy to commit wire fraud existed; (2) that the defendant knew of
    it; and (3) that the defendant knowingly and voluntarily joined it. Feldman,
    931 F.3d at 1257. In turn, the elements of conspiracy to commit money laun-
    dering, in violation of 
    18 U.S.C. § 1956
    (h), are “(1) an agreement between two
    or more persons to commit a money-laundering offense; and (2) knowing and
    voluntary participation in that agreement by the defendant.” United States v.
    Iriele, 
    977 F.3d 1155
    , 1174 (11th Cir. 2020) (quoting United States v. Feldman,
    
    936 F.3d 1288
    , 1307 (11th Cir. 2019)). Relevant to Fisher’s money laundering
    conspiracy conviction, money laundering offenses include “the use of a finan-
    cial institution to conduct a monetary transaction involving more than $10,000
    of illegally obtained funds.” 
    Id.
     at 1173 (citing 
    18 U.S.C. § 1957
    ).
    USCA11 Case: 21-11879            Date Filed: 09/13/2022         Page: 36 of 48
    36                         Opinion of the Court                       21-11879
    1. Direct Evidence from Burton’s Testimony
    At trial, the most direct evidence of Fisher’s knowledge was
    Burton’s testimony that Fisher knew the Dr. Traub prescriptions
    had no doctor-patient relationship behind them. Burton, the or-
    chestrator of the conspiracy, testified that he told Fisher in their
    initial call that Dr. Traub “didn’t actually see the patients” for
    which the prescriptions were written. Fisher responded that “as
    long as it’s not a problem with the surgeon, I have no problem with
    it.” Burton also testified that he discussed “the fact that these pre-
    scriptions didn’t have a real doctor/patient behind them” with
    Fisher “[m]any times,” and told Fisher that one of Burton’s sales
    representatives recruited patients at a bachelor party.
    On appeal, Fisher claims Burton’s testimony is insufficient
    for two reasons: (1) there was no evidence Fisher knew about
    Hodgson’s role in the scheme and “the essence of the govern-
    ment’s case was that Fisher supposedly knew all along that Dr.
    Traub was oblivious to the scheme that Hodgson and Burton were
    perpetrating”; and (2) the government presented no evidence of
    Again, Fisher’s arguments on appeal only pertain to whether he conspired to
    commit health care fraud. But even presuming that Fisher meant to argue
    that all three of his convictions should be overturned because he did not know
    of the Burton-Hodgson conspiracy, or because he did not knowingly and vol-
    untarily join it, there was sufficient evidence to prove that he did for the same
    reasons we find that there was sufficient evidence to convict him for conspir-
    acy to commit health care fraud. Therefore, we need not separately address
    the sufficiency of the evidence supporting his other convictions, as our analysis
    would be the same.
    USCA11 Case: 21-11879       Date Filed: 09/13/2022     Page: 37 of 48
    21-11879               Opinion of the Court                        37
    what constitutes a valid doctor-patient relationship, and under
    Georgia law, it is possible to establish a doctor-patient relationship
    without seeing the patient. Both arguments are unpersuasive.
    First, it does not matter that Fisher did not know about
    Hodgson’s role in the scheme. “[A] defendant can be convicted of
    conspiracy if the evidence demonstrates that he was aware of the
    conspiracy’s essential nature, even if he did not know all of its de-
    tails, played only a minor role in the overall scheme, did not have
    direct contact with other alleged co-conspirators, or did not partic-
    ipate in every stage of the conspiracy.” Abovyan, 988 F.3d at 1302–
    03 (quoting Sosa, 777 F.3d at 1290). Here, the essential nature of
    the scheme was submitting prescriptions to TRICARE that were
    not made pursuant to a licensed practitioner’s determination that
    the prescriptions were medically necessary. And a reasonable jury
    could have construed Burton’s testimony to mean that Fisher was
    comfortable joining the scheme because Fisher thought a dishonest
    doctor, rather than a dishonest doctor’s assistant, was on board
    with it and willing to write prescriptions without having a doctor-
    patient relationship. See Estepa, 998 F.3d at 908 (“We may not
    overturn the jury’s verdict ‘if any reasonable construction of the
    evidence would have allowed the jury to find the defendant guilty
    beyond a reasonable doubt.’” (quoting Capers, 708 F.3d at 1297)).
    Second, as to Fisher’s argument that it was possible for Dr.
    Traub to establish a valid doctor-patient relationship through re-
    mote consultations without actually seeing the patients, “it is not
    necessary that the evidence exclude every reasonable hypothesis of
    USCA11 Case: 21-11879            Date Filed: 09/13/2022          Page: 38 of 48
    38                         Opinion of the Court                        21-11879
    innocence or be wholly inconsistent with every conclusion except
    that of guilt” because “a jury is free to choose among the reasona-
    ble constructions of the evidence.” United States v. Iriele, 
    977 F.3d 1155
    , 1168 (11th Cir. 2020) (quoting United States v. Godwin, 
    765 F.3d 1306
    , 1320 (11th Cir. 2014)). And one reasonable construction
    of the evidence at trial was that Dr. Traub had no relationship at all
    with the relevant TRICARE patients. For example, Burton testified
    that Burton discussed “the fact that these prescriptions didn’t have
    a real doctor/patient relationship behind them” with Fisher
    “[m]any times,” and that he told Fisher that one of his sales repre-
    sentatives recruited “patients” at a bachelor party. In hearing testi-
    mony that Fisher was told “[m]any times” that Dr. Traub didn’t
    have a real doctor-patient relationship with the relevant patients,
    and that some of these patients were recruited to be patients at a
    bachelor party, the jury was “not required to put aside its common
    sense or to assume that [Fisher] ha[d] none.” 9 United States v. Hill,
    
    643 F.3d 807
    , 863 (11th Cir. 2011). We now turn to the circumstan-
    tial evidence presented at trial.
    9 Common sense also refutes Fisher’s argument that, because Fisher was not
    a doctor or a pharmacist, he could not have been expected to know what was
    necessary to establish a legitimate doctor-relationship. Cf. Gonzalez, 834 F.3d
    at 1216 (“Gonzalez’s lack of formal nursing or medical training would not have
    affected her ability to recognize the suspicious nature of the activities in which
    she was engaged.”). Fisher’s argument is also undercut by the circumstantial
    evidence discussed in Section III(A)(2).
    USCA11 Case: 21-11879        Date Filed: 09/13/2022     Page: 39 of 48
    21-11879                Opinion of the Court                        39
    2. Circumstantial Evidence
    “It is well settled that the government may prove a conspir-
    acy through circumstantial evidence or inferences from the defend-
    ant’s conduct.” Abovyan, 988 F.3d at 1303. Here, circumstantial
    evidence also supported the verdict. This circumstantial evidence
    as discussed below included Fisher’s “gray area” pharmacy prac-
    tices, his conduct surrounding the letter affidavits, his (lack-of) re-
    sponse to Cowart’s alerting him to suspected fraud, and the evi-
    dence elicited at trial that he was trying to cover up the scheme.
    We first address the gray area practices.
    i. Gray Area Practices
    While not illegal in and of themselves, a reasonable jury
    could view Fisher’s “gray area” pharmacy practices as showing
    Fisher’s willingness to profit off of TRICARE at any cost. For ex-
    ample, the government presented evidence that Fisher did not en-
    force the co-pay requirement if collecting a co-pay would put the
    ability to bill TRICARE for the prescription in jeopardy. And
    Fisher admitted to Agent Carmona that he “took advantage” of
    TRICARE’s high reimbursement rates by charging as much as he
    could, even though he admitted those costs were “inflated.”
    Fisher argues that evidence of his lax co-pay policies and use
    of expensive ingredients was insufficient to sustain his conviction.
    But Fisher concedes that “[t]here was evidence at trial that certain
    practices of [Physician Specialty Pharmacy] violated various regu-
    latory requirements and policy manuals of TRICARE and [Express
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 40 of 48
    40                     Opinion of the Court                21-11879
    Scripts].” And, in addition to other evidence demonstrating that
    Fisher knew of, and knowingly and voluntarily joined, the relevant
    conspiracy, a reasonable jury could infer that Fisher’s “gray area”
    pharmacy practices are consistent with an intent to defraud
    TRICARE and to maximize his profits from so doing.
    ii. The Letter Affidavit
    The evidence at trial showed that Fisher also sent a letter
    affidavit to Burton for Dr. Traub to sign, which stated, in relevant
    part: “My name is Dr. Jeff Traub. . . . As a treatment for my pa-
    tients, I have written compounding prescriptions. In all cases, I
    personally met with each patient for whom I wrote a prescription.”
    (Emphasis added). And in connection with this letter, Burton tes-
    tified that Fisher knew Dr. Traub did not meet with each patient.
    Nonetheless, Fisher returned the letter affidavit to Burklow’s attor-
    ney to submit to Express Scripts. A reasonable jury could conclude
    that this evidence suggested that Fisher knowingly participated in
    the conspiracy and that he knowingly tried to ensure that the
    scheme would continue without detection.
    iii. Fisher’s Response to Report of Suspected Fraud
    The evidence presented at trial also showed that Fisher did
    not act when Cowart reported a patient’s complaint of suspected
    fraud, or when Cowart told Fisher that she suspected that several
    patients simply filled out questionnaires provided by Dr. Traub and
    were never actually seen by the doctor. A reasonable jury could
    infer that Fisher did not investigate the suspected fraud because he
    USCA11 Case: 21-11879         Date Filed: 09/13/2022     Page: 41 of 48
    21-11879                Opinion of the Court                          41
    already knew of the fraudulent scheme and that Dr. Traub had not
    seen the relevant patients. That inference is even more reasonable
    given other testimony at trial that the patient who complained of
    suspected fraud was one of the patients that was recruited at a bach-
    elor party.
    iv. Evidence of Cover-Up
    We now turn to the circumstantial evidence elicited at trial
    regarding a cover-up. A reasonable jury could view Fisher’s deci-
    sion to buy Jay Pharmacy, and Fisher’s inconsistent statements to
    Agent Carmona, as attempts to cover-up his role in the conspiracy.
    McKnight—the operations manager of Physician Specialty
    Pharmacy—testified that Fisher purchased Jay Pharmacy in part to
    spread out high insurance billing and because “being a small phar-
    macy, it probably wouldn’t draw a lot of attention . . . “[f]rom the
    insurance companies.” A reasonable jury could conclude that
    McKnight’s testimony, in combination with an email Fisher sent
    about wanting to purchase other pharmacies because “insurance
    companies actively target pharmacies that bill over a certain
    amount per month, so having multiple pharmacies billing a lower
    amount . . . is an ideal strategy for staying off their radar,” suggested
    that Fisher knew of the conspiracy to defraud TRICARE and that
    he attempted to conceal it.
    Fisher also made inconsistent statements to Agent Car-
    mona, which a reasonable jury could view as an attempt by Fisher
    to cover up his role in the conspiracy. For example, Fisher told
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 42 of 48
    42                     Opinion of the Court                21-11879
    Agent Carmona that he did not know why Burklow Pharmacy lost
    its contract with Express Scripts, even though the evidence at trial
    demonstrated that Fisher received the DOD letter two months ear-
    lier. He also stated to Agent Carmona that his sales representatives
    did not recruit patients, but Fisher later told Agent Carmona that
    his sales representatives did market directly to TRICARE benefi-
    ciaries.
    ****
    Based on this record, our decisions in United States v. Grow,
    
    977 F.3d 1310
     (11th Cir. 2020), and United States v. Chalker, 
    966 F.3d 1177
     (11th Cir. 2020), support our conclusion that there was
    sufficient evidence to support the verdicts in this case.
    The scheme in Grow involved TRICARE patients recruited
    to receive “pain creams, scar creams, and vitamins that were not
    medically necessary.” 977 F.3d at 1321. The defendant, Grow,
    owned a marketing company that employed sales representatives
    to recruit TRICARE beneficiaries to receive compound medica-
    tions from the pharmacy he worked with. Id. at 1314–15. Grow
    would forward patient information to a telemedicine company,
    which would arrange for a doctor to “conduct a brief consult—typ-
    ically between five and seven minutes, but sometimes as short as
    three minutes—and prescribe [the pharmacy’s] creams and vita-
    mins.” Id. at 1315. Once a doctor issued a prescription, the tele-
    medicine company would fax it to Grow, who would then fax it to
    the pharmacy to fill. Id. The pharmacy would mail the
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 43 of 48
    21-11879               Opinion of the Court                       43
    prescriptions to the patient and submit a claim for reimbursement.
    Id. The pharmacy would charge the patients a co-pay, but Grow
    told the patients they did not need to pay their co-pays because the
    pharmacy would never collect on them. Id. If the pharmacy did
    seek to collect the co-pay, Grow told his representatives they could
    pay the co-pay on the patient’s behalf. Id.
    In connection with the above-described scheme, Grow was
    convicted for, among other things, conspiracy to commit health
    care and wire fraud. Id. at 1320. Grow appealed his conviction on
    the basis that the evidence was insufficient to support the verdict.
    Id. We upheld Grow’s conviction for conspiracy to commit health
    care fraud because there was sufficient evidence to support the con-
    viction, including “sufficient evidence of Grow’s knowledge of the
    fraud and his intent to defraud.” Id. at 1322.
    Like Fisher, the evidence showed that Grow pushed the
    pharmacy to use a premium ingredient in its compound medica-
    tions that was vastly more expensive but otherwise identical to the
    regular ingredient. Id. at 1323. This Court determined that “a jury
    could reasonably conclude that Grow and [the pharmacy] used [the
    expensive ingredient] for no other reason than to fraudulently in-
    flate Tricare’s reimbursement rates.” Id. at 1324; see also United
    States v. Melgen, 
    967 F.3d 1250
    , 1255, 1263 (11th Cir. 2020) (reject-
    ing sufficiency of the evidence challenge because there was suffi-
    cient evidence of the defendant’s “motive and means for fraudu-
    lently billing [an insurance company] for an expensive drug” and
    USCA11 Case: 21-11879       Date Filed: 09/13/2022     Page: 44 of 48
    44                     Opinion of the Court                 21-11879
    the defendant “only rarely prescribed” the equivalent, less expen-
    sive drug).
    Like Fisher, Grow profited from the fraud. Grow, 977 F.3d
    at 1324. As we have explained, “[e]vidence that the defendant prof-
    ited from a fraud may . . . provide circumstantial evidence of the
    intent to participate in that fraud.” United States v. Machado, 
    886 F.3d 1070
    , 1083 (11th Cir. 2018). As such, this Court concluded that
    “a reasonable jury could find an intent to defraud from the money
    Grow made from billing [TRICARE] for creams and vitamins that
    were not medically necessary.” Grow, 977 F.3d at 1324. And, like
    Fisher, there was evidence from which a reasonable jury could find
    “that Grow and [the pharmacy] were trying to conceal the fraud
    scheme.” Id. at 1325. For example, Grow would remove his fax
    number from the prescriptions he submitted to the pharmacy be-
    cause only doctors were allowed to submit prescriptions to the
    pharmacy. Id. at 1324–35. Moreover, when Grow became con-
    cerned that there might be an issue with having a pharmacy paying
    commissions to independent contractors because it would violate
    the anti-kickback statute, Grow and the pharmacy decided that
    “everybody had to become W-2 employees.” Id. at 1325; see also
    United States v. Davis, 
    490 F.3d 541
    , 549 (6th Cir. 2007) (noting that
    intent to defraud “can be inferred from efforts to conceal the un-
    lawful activity”). Given the similarities between the evidence in
    the two cases, here, like in Grow, we conclude that the evidence
    was sufficient to support the jury’s verdict.
    USCA11 Case: 21-11879       Date Filed: 09/13/2022    Page: 45 of 48
    21-11879               Opinion of the Court                       45
    Our decision in United States v. Chalker, 
    966 F.3d 1177
     (11th
    Cir. 2020) also supports our holding. The scheme in Chalker in-
    volved submitting fraudulent claims to Medicare, Medicaid, and
    TRICARE for reimbursement. 
    Id. at 1182
    . Chalker was the phar-
    macist-in-charge of a pharmacy in Florida. 
    Id.
     The pharmacy,
    “with Chalker at the helm, filled medically unnecessary prescrip-
    tions for patients who neither wanted nor needed them.” 
    Id. at 1185
    . Chalker was convicted by a jury for, among other things,
    conspiracy to commit health care fraud. 
    Id. at 1182
    . Chalker chal-
    lenged his conviction, among other grounds, on the basis that the
    evidence was insufficient to support the verdict. 
    Id.
     We upheld
    the verdict because the government “introduced more than
    enough evidence to establish that Chalker knowingly and volun-
    tarily participated in the conspiracy.” 
    Id. at 1187
    .
    Similar to Burton’s testimony about Fisher’s role in the
    fraud, Chalker’s co-conspirator “admitted that he had conspired
    with Chalker to commit health-care fraud.” 
    Id.
     And, just as
    Fisher’s employees testified, Chalker’s co-conspirator testified that
    the pharmacy “had a very lax view on co[-]pays and would waive
    them quite often.” 
    Id.
     (internal quotation marks omitted).
    Similar to Fisher’s trial system for creating formulas that
    would obtain higher reimbursements, “Chalker engaged in test
    billing: he ‘would test run different formulations with the insur-
    ance companies to see what was covered, what was not covered, if
    it was covered, what was the net profit, and if [it] wasn’t high
    enough, we would still try to find other formularies that would
    USCA11 Case: 21-11879         Date Filed: 09/13/2022      Page: 46 of 48
    46                      Opinion of the Court                   21-11879
    reimburse higher.’” 
    Id.
     And just as Fisher submitted the letter af-
    fidavit for the Burklow Pharmacy audit, knowing Dr. Traub had
    not personally seen all of the patients, Chalker sent a recertification
    agreement to a pharmacy benefits manager stating that no owner
    of the pharmacy had faced criminal prosecution for fraud, knowing
    that it was untrue. 
    Id. at 1188
    .
    “A jury’s verdict cannot be overturned if any reasonable con-
    struction of the evidence would have allowed the jury to find the
    defendant guilty.” Melgen, 967 F.3d at 1263 (quoting Capers, 708
    F.3d at 1297). For the reasons discussed, we hold that there was
    sufficient evidence to allow the jury to find Fisher guilty of conspir-
    acy to commit health care fraud. Because Fisher relied on his ar-
    guments for overturning his health care fraud conspiracy convic-
    tion to overturn his other convictions, we need not separately ad-
    dress them. See supra n.8.
    B. Constructive Amendment
    On appeal, Fisher also argues that the district court’s failure
    to limit the jury’s consideration of the alleged means of accomplish-
    ing the conspiracy amounted to approving a constructive amend-
    ment of the indictment. Specifically, Fisher contends that the ad-
    mission of the “gray area” evidence at trial amounted to a construc-
    tive amendment of the indictment and, therefore, the district court
    should have provided a limiting instruction to the jury. 10
    The indictment alleged that Fisher conspired to seek reimbursements from
    10
    TRICARE for fraudulent prescriptions, sought reimbursements for
    USCA11 Case: 21-11879             Date Filed: 09/13/2022         Page: 47 of 48
    21-11879                    Opinion of the Court                                47
    “The Fifth Amendment guarantees that a defendant can be
    convicted only of crimes charged in the indictment.” Holt, 777
    F.3d at 1261. A constructive amendment occurs “when the essen-
    tial elements of the offense contained in the indictment are altered
    to broaden the possible bases for conviction beyond what is con-
    tained in the indictment.” Id. (quoting United States v. Narog, 
    372 F.3d 1243
    , 1247 (11th Cir. 2004)). “The indictment can be ex-
    panded, either literally or in effect, by the prosecutor’s actions or
    the district court’s instructions.” 
    Id.
    “A constructive amendment ‘is per se reversible error.’” 
    Id.
    (quoting Narog, 
    372 F.3d at 1247
     (italics omitted)). But even if
    Fisher’s constructive amendment argument has merit, Fisher
    waived this argument. Fisher failed to raise this argument when
    the court charged the jury, instead waiting until his post-verdict
    motion for acquittal and new trial. Generally, we review an unpre-
    served constructive amendment claim only for plain error. See
    United States v. Maradiaga, 
    987 F.3d 1315
    , 1322–23 (11th Cir. 2021);
    Holt, 777 F.3d at 1261. But “when a party agrees with a court’s
    prescriptions while not seeking to enforce the co-pay requirement that was
    part of the TRICARE contract, and directed his employees to use needlessly
    expensive ingredients in compound medications to maximize the reimburse-
    ments Fisher’s pharmacy could bill to TRICARE. At trial, the government
    also presented evidence of Physician Specialty Pharmacy’s: (1) out-of-state
    sales of compound medications; (2) delivery of medications to Burton’s home
    address in Georgia for patients located out-of-state; (3) use of force-fill orders;
    (4) failure to reimburse for returned medications; (5) seeking 90-day refills; and
    (6) unconventional central fill set-up with Burklow Pharmacy.
    USCA11 Case: 21-11879        Date Filed: 09/13/2022    Page: 48 of 48
    48                     Opinion of the Court                 21-11879
    proposed instructions, the doctrine of invited error applies, mean-
    ing that review is waived even if plain error would result.” Frank,
    
    599 F.3d at 1240
    . On the last day of trial, before dismissing the jury
    to deliberate, the district court asked whether Fisher objected to
    the jury instructions, to which his attorney responded, “No objec-
    tion, Your Honor.” Fisher has therefore waived his right to chal-
    lenge this argument on appeal. Cf. United States v. Fulford, 
    267 F.3d 1241
    , 1247 (11th Cir. 2001) (“[H]aving agreed to the court’s
    proposed instruction, Gage appears to have waived his right to
    challenge that instruction on appeal.”). Because Fisher invited the
    error, we need not address the merits of his argument.
    IV.    CONCLUSION
    For all these reasons, we hold that the government pre-
    sented sufficient evidence to support Fisher’s conspiracy convic-
    tions and that Fisher waived review of his constructive amendment
    argument. We therefore affirm Fisher’s convictions for conspiracy
    to commit health care fraud, in violation of 
    18 U.S.C. §§ 1347
    , 1349;
    conspiracy to commit wire fraud, in violation of 
    18 U.S.C. §§ 1343
    ,
    1349; and conspiracy to commit money laundering in violation of
    
    18 U.S.C. §§ 1956
    (h), 1957, as well as the corresponding sentence
    and order of forfeiture.
    AFFIRMED.